Imran (@ImranHouse) header
Imran (@ImranHouse) profile picture

Biologist. Views are my own.

Joined August 2009
Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)Photo by Imran (@ImranHouse)
Excited to share that my PhD work is out in @Nature today! We engineered armoured CAR T cells to express therapeutic payloads only at the tumour site, to improve their safety and efficacy for the treatment of solid cancers. 1/14 nature.com/articles/s41586-0…
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We do blogs now too ❤️ @oNKo_innate onko-innate.com/learning-cen…
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Super great to have this chat with @JunyunLai about all things oNKo, immunotherapy and career change. Thanks for the opportunity @Synthego @KevinHoldenSF @dr_beccles
Two of our senior scientists, @ImranHouse & @JunyunLai, were guests on @Synthego's CRISPR Cuts podcast recently to discuss their work at oNKo generating novel therapies for solid tumors. Thanks for having us, @KevinHoldenSF & @dr_beccles! #Cancer synthego.com/podcast/imran-h…
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Protein engineering and biotherapeutics: building tools & therapies for the #immunooncology revolution 💡 At oNKo-innate, we've developed an advanced #proteinengineering and #biotherapeutics platform: onko-innate.com/platforms
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Spotlight on our oNKo-001 therapy for solid tumors! oNKo-001 is a reduced-potency IL-12 fusion protein that overcomes several major issues that have hampered the clinical translation of IL-12. Read more on our pipeline page: onko-innate.com/pipeline/pip… #cytokines #cancertreatment
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For all those who have asked me “so like, what do you guys work on? Is it like, NK stuff?” …. Here is, finally, the answer. Enjoy!!
🚨Introducing the new and improved oNKo-innate! onko-innate.com/ Here at oNKo, we’re reshaping the future of #immunooncology 💉🧬🧪 Get to know us better by exploring our new website, and join the immuno-oncology revolution! #cancertherapy #Immunotherapy
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Thank you @IanParish_AU for an excellent talk! So much clarity in an otherwise muddled world of T cell biology.
It was a true please to host @IanParish_AU yesterday at @oNKo_innate HQ for an exquisitely delivered talk on T cell states relevant to cancer. I encourage anyone interested in the field to reach out to him. Thanks @ImranHouse for setting this up
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This week we’re celebrating our newly appointed Chief Technology Officer, @DrIvaNikolic 👏 As CTO, Iva will drive the development and implementation of new technologies, enabling discoveries that will form the basis for a new wave of #cancertherapies. Congrats, Iva!
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OUR NEW AD IS LIVE!   You’re the Voice that will make history.   On 14 October, we know we all can stand together with the power to be powerful.   #HistoryIsCalling, so #VoteYes. Are you in? John Farnham is.   #UluruStatement #StayTrue2Uluru #YoureTheVoice #VoteYes
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Massive congratulations to Emily Derrick (@emsderrick) and @paulbeavis4 and team on the work. Is excellent to have this out in the world. cell.com/cell-reports/pdf/S2…
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One of my favourite things about the paper is the use of rapid gene KO bone marrow chimeras which wouldn’t have happened without @JunyunLai and proved an incredibly versatile tool for unpicking some of the biology of Cxcl9
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Thank you also to the funders of the work @VicGovDH @NBCFAus @PeterMacRes
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It’s kind of amazing that an active journalist can make negative public comment about a politician. Thank god he doesn’t work for a medical research institute.
If Hawaii is on fire, where does Scomo flee to?
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I’m a bit slow on this but faaaaaarrrrrrrrkkkk
Chloe Kelly, always delivering when it matters! Nerves of steel! 🏴󠁧󠁢󠁥󠁮󠁧󠁿 #ENGNGA
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Chloe Kelly, always delivering when it matters! Nerves of steel! 🏴󠁧󠁢󠁥󠁮󠁧󠁿 #ENGNGA
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Our latest work is out @ImmunityCP ! Find out how we used surface proteome analyses to explore circulating and tissue-resident memory T cells diversity across tissues & many more!👇 authors.elsevier.com/c/1hL2j… @LMackayLab @TheDohertyInst #teamTRM 🧪🔬🧵
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2/ Main findings: - Last author of paper is 20% more likely to be credited as IP inventor than 1st author. - This is more skewed in #biology and less in #engineering. - Female 1st authors are much more likely to be *excluded* from patents than male 1st authors.
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Very exciting day for oNKo. Onwards and upwards. (And finally my experience as a factory worker have come in handy. You should have seen me on the pallet jack during the move.)
New office views 😍 With much excitement, @onko_innate starts a new chapter this week occupying 2 floors of the @BakerResearchAu at 75 Commercial Rd, Melbourne. Do not hesitate to get in touch for opportunities to collaborate.
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