Published today in @LancetRespirMed is the final report of @prismtrial, an international multi-centre phase-3 randomised trial of routine postoperative CPAP to prevent pneumonia, re-intubation & death after major abdominal surgery sciencedirect.com/science/ar… @rupert_pearse @QMULWHRI

Published today in @BJAJournals are two papers describing the impact of SARS-CoV-2 on surgical patients in England and Wales led by teams from @QMULWHRI & @SwanseaUni @Tom__Dobbs @rupert_pearse @_alexfowler @CCPMG_TEAM bjanaesthesia.org/article/S0… & bjanaesthesia.org/article/S0…

1/ Increasing numbers of patients aged 75 or older are undergoing surgery, but it is unclear whether these treatments are needed or whether they improve quality of life. academic.oup.com/bjs/article… @_alexfowler @rupert_pearse @BJSurgery

1/Our analysis of all surgery in England since start of the pandemic found that patients with SARS-CoV-2 have much greater risk of death compared to patients without infection. medrxiv.org/content/10.1101/… @rupert_pearse @_alexfowler @Tom__Dobbs @CCPMG_TEAM

We estimate that the financial cost of clearing the current backlog of postponed operations in @NHSEngland is ~£1.3bn. This could increase to over ~£5bn by March 2021 as the reintroduction of elective surgery will be gradual. medrxiv.org/content/10.1101/… (Pre-print. Not peer-reviewed)

Our modelling analysis suggests that ~750,000 operations may have already been postponed in @NHSEngland due to COVID-19, which could increase to ~2.2 million by March 2021 as elective surgery is gradually reintroduced medrxiv.org/cgi/content/shor… (Pre-print. Not yet peer-reviewed).

4700 participants recruited to @prismtrial !!! Only 100 to go! This is a fantastic achievement and we are now very close to the end! Thank you to all involved. Can we finish by the end of October? @rupert_pearse

Amazing effort by all investigators. Thank you for all the hard work. With just over 600 participants left to recruit, let’s aim to finish before August!

Thanks @rupert_pearse! Team effort, including: @mkphull @buzzlogic @BruceBiccard @gillies_mike and @ISOSstudy investigators. Great example of collaborative international research 🙂👍👌@QMULWHRI @WHO @BJAJournals

Relationship between preoperative anaemia and risk of complications after surgery. New data from @ISOSstudy & @buzzlogic. doi.org/10.1016/j.bja.2018.0… @QMULWHRI @rupert_pearse

Moderate and severe anaemia associated with increased risk of death after surgery. New data from @ISOSstudy & @buzzlogic. doi.org/10.1016/j.bja.2018.0… @QMULWHRI @rupert_pearse

@denny_levett on benefit of post-op ICU. Observational data suggest no benefit post-op ICU admission compared to ward-based care. @ISOSstudy @EBPOM #EBPOM18

Mev Gooneratne on intra-op hypotension @triperioperati1 #ebpom18

Assessment of functional capacity before major non-cardiac surgery: results of the METS study. thelancet.com/journals/lance…