This is the account of the ICOD Project funded by European Union and designed to communicate with Down syndrome Families and associations

Italy
Joined November 2022
A Great Thanks to the Italian T21 Task Force for this wonderful 10th Congress in Naples where we had the opportunity to update DS families and associations on the recent updates of our European ICOD project! #Hadea #T21taskforce #AELISFARMA #IMIM
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A Great Advance for Our European ICOD Project !! A Great Thanks to #DS families #DSassociations #AIPD #CoorDown #Futuro21 #Hadea #EuropeanCommission โ€“ at Gizzeria, Calabria
๐Ÿš€ A major milestone for the clinical development of AEF0217. The IDMC has recommended that Aelis Farmaโ€™s Phase 2b study of AEF0217 in people with Down syndrome continue as planned, without any modification to the protocol. ๐Ÿ”— Read the full PR: s3.eu-central-1.amazonaws.coโ€ฆ
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A Great Talk from Our Coordinator Rafael De La Torre at the International Workshop on "Therapeutic Perspectives for Intellectual Disability in Down Syndrome " A great thanks to #T21 Italian TaskForce for this opportunity! #hadea #icodproject #aelisfarma #DS #IMIM
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A great honor to participate as Italian Deputy for IHI network to the meeting at our Senate of the Republic about โ€œScience for all" !! A Great Occasion to discuss also about dissemination activities for DS families in our European ICOD Project A great Thanks to #Esperia #HaDEA
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ICOD_Project retweeted
On #WorldDownSyndromeDay, discover how EU-funded research is contributing to enhancing our understanding of Down syndrome and improving the cognitive development, autonomy and quality of life of people living with this condition. ๐Ÿ”—hadea.ec.europa.eu/news/worlโ€ฆ #H2020
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ICOD_Project retweeted
#WorldDownSyndromeDay AEF0217 : The first patient first visitsย in our Phase 2B clinical trialย were completed in December 2025, marking the successfulย operational launch of the study. Today, screening and recruitment are actively underwayย across participating centres in Europe.
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We will wait with our ICOD coordinator Rafael De La Torre tomorrow at 18,00 for the T21RS | Webinar 27 | The European ICOD project: new evidence for DS families!! Thank you #T21RS Education Committee,#IMIM #hadea See you on ZOOM us02web.zoom.us/w/8697701056โ€ฆ
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ICOD_Project retweeted
๐Ÿงฌ International Rare Disease Day โ€“ Feb 28 At Aelis Farma, we are convinced that therapeutic innovation in rare diseases also requires exploring new biological mechanisms.
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ICOD_Project retweeted
โ€œTherapeutic Perspectives for Intellectual Disability in Down Syndromeโ€. Workshop promosso dallโ€™AIPD โ€“ Associazione Italiana Persone con Sindrome di Down, sezione di Potenza, in collaborazione con la Task Force Italiana sulla Trisomia 21.
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ICOD_Project retweeted
Happy to share our third publication of @ICOD_Project where we demonstrate that low IL-18 free levels contribute with high TNF-alfa and reduced TGF-ฮฒ1 plasma levels to cognitive decline in Down syndrome and also suggest news target to treat cognitive decline in DS!! #Hadea #IMIM
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Happy to share our third publication of @ICOD_Project where we demonstrate that low IL-18 free levels contribute with high TNF-alfa and reduced TGF-ฮฒ1 plasma levels to cognitive decline in Down syndrome and also suggest news target to treat cognitive decline in DS!! #Hadea #IMIM
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A great Advance for Our ICOD Project! Aelis Farma receives a positive opinion from EMA Pediatric Committee on the Pediatric Investigation Plan for AEF0217 in Down syndrome! @EU_HaDEA @EU_Commission @AelisFarma #IMIM #Icodproject #DS news.newcontact.eu/images/clโ€ฆ
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Great news and a great advance for DS families!! Ready to start with the Phase 2B study !! Thanks to #EuropeanCommission #Icodproject #aelisfarma #Hadea #EMA #AIFA #IMIM #OasiResearchInstitute #UniCT
๐Ÿ‘‰ ๐—” ๐—บ๐—ฎ๐—ท๐—ผ๐—ฟ ๐˜€๐˜๐—ฒ๐—ฝ ๐˜๐—ผ๐˜„๐—ฎ๐—ฟ๐—ฑ๐˜€ ๐—ฎ ๐—ฝ๐—ผ๐˜๐—ฒ๐—ป๐˜๐—ถ๐—ฎ๐—น ๐˜๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—ฐ๐—ผ๐—ด๐—ป๐—ถ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ฑ๐—ถ๐˜€๐—ผ๐—ฟ๐—ฑ๐—ฒ๐—ฟ๐˜€ ๐—ฎ๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ฒ๐—ฑ ๐˜„๐—ถ๐˜๐—ต ๐——๐—ผ๐˜„๐—ป ๐˜€๐˜†๐—ป๐—ฑ๐—ฟ๐—ผ๐—บ๐—ฒ. s3.eu-central-1.amazonaws.coโ€ฆ
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ICOD_Project retweeted
๐Ÿ‘‰ ๐—” ๐—บ๐—ฎ๐—ท๐—ผ๐—ฟ ๐˜€๐˜๐—ฒ๐—ฝ ๐˜๐—ผ๐˜„๐—ฎ๐—ฟ๐—ฑ๐˜€ ๐—ฎ ๐—ฝ๐—ผ๐˜๐—ฒ๐—ป๐˜๐—ถ๐—ฎ๐—น ๐˜๐—ฟ๐—ฒ๐—ฎ๐˜๐—บ๐—ฒ๐—ป๐˜ ๐—ผ๐—ณ ๐—ฐ๐—ผ๐—ด๐—ป๐—ถ๐˜๐—ถ๐˜ƒ๐—ฒ ๐—ฑ๐—ถ๐˜€๐—ผ๐—ฟ๐—ฑ๐—ฒ๐—ฟ๐˜€ ๐—ฎ๐˜€๐˜€๐—ผ๐—ฐ๐—ถ๐—ฎ๐˜๐—ฒ๐—ฑ ๐˜„๐—ถ๐˜๐—ต ๐——๐—ผ๐˜„๐—ป ๐˜€๐˜†๐—ป๐—ฑ๐—ฟ๐—ผ๐—บ๐—ฒ. s3.eu-central-1.amazonaws.coโ€ฆ
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ICOD_Project retweeted
Dr Pier Vincenzo PIAZZA was interviewed by Lโ€™Esprit Curieux ๐ŸŽ™๏ธ Watch the full interview here: youtube.com/watch?v=1S-7KkOKโ€ฆ
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A Great Thanks to the Italian DS Task Force and this Round Table where we have had the opportunity to discuss with DS associations about Innovative drugs and Autonomy fir DS!! #Icodproject #DSTaskForce #IMIM #aelis #EuropeanUnion
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Now in @NatureNeuro! Thanks to a big collaborative effort, we have created a new tool to enhance mitochondrial function using DREADDS. This results in increased oxygen consumption and rescues cognitive deficits in cannabinoid- treated mice, and in Alzheimer and dementia models!
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ICOD_Project retweeted
A strong immune system may be key to preventing Alzheimerโ€™s disease. People with higher titers of anti-viral antibodies were less likely to have dementia. @NIHAging ow.ly/lM6x50WehAH
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Seminari #Neurociรจncies @hospitaldelmar - @HMar_research ๐Ÿ“… Dijous 19 de juny ๐Ÿ•— 08:00 h ๐Ÿ“Sala Josep Marull ๐Ÿ—ฃ๏ธ Dr. Eduard Vieta @hospitalclinic @idibaps ๐ŸŽฏ Actualitzaciรณ i novetats en trastorn bipolar ๐Ÿ‘‰researchmar.net/agenda/963
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