@HwangLab

Pancreatic Cancer Research Lab @UCDavis. Department of Microbiology and Molecular Genetics. 241B Briggs Hall.

cihwang.com
Joined May 2018
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biology.ucdavis.edu/news/dis…

Discovery Could Help Prevent Cancer Drug Resistance Before It Starts

Cancer cells are quick to develop resistance to anti-tumor drugs. New research by scientists from the University of California, Davis shows how cancers adapt to evade a class of anti-tumor drugs...

biology.ucdavis.edu
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Join us for Sonia's PhD Exit Seminar 🎓 @GGIPstudents @HwangLab @MmgUcd March 4th, 4:10pm, Green hall 1022. Please join us to celebrate her achievements. cihwang.wordpress.com/2026/0…
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.@UCD_Cancer has officially been designated a National Pancreas Foundation Center of Excellence! This prestigious accolade marks the dedication to advancing treatment and care for pancreatic cancer patients. Read more here: bit.ly/4iQ096n Designation @UCDavisHealth
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November is pancreatic cancer awareness month. We wear purple to raise awareness of this disease. @ucdavis @ucdavisbiology @UCD_Cancer @HwangLab cihwang.wordpress.com/2025/1…
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🚨 New preprint alert from @HwangLab! 🚨 First author: Suyakarn (Sonia) Archasappawat BRD2 Upregulation as a Pan-Cancer Adaptive Resistance Mechanism to BET Inhibition 👉 biorxiv.org/content/10.1101/… 🧵 (1/9)

BRD2 Upregulation as a Pan-Cancer Adaptive Resistance Mechanism to BET Inhibition

Bromodomain and extraterminal motif (BET) inhibitors, such as JQ1, are promising cancer therapeutics that target epigenetic regulators, particularly BRD4. However, resistance to BET inhibitors (BETi)...

biorxiv.org
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Senate panel rejects Trump cuts to NIH, other health agencies thehill.com/homenews/senate/…

Senate panel rejects Trump cuts to NIH, other health agencies

The Senate Appropriations Committee rejected the Trump administration’s massive proposed funding cut to the National Institutes of Health (NIH), advancing a measure that would increase the agency’s…

thehill.com
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I am honored to receive the Chancellor's Award for Excellence in Mentoring Undergraduate Research. This recognition belongs to the talented undergrad students who I've had privilege to work with. @ucdavis @MmgUcd @ucdavisbiology @HwangLab cihwang.wordpress.com/2025/0…
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My home department @MmgUcd @ucdavisbiology @ucdavis is recruiting a faculty member (Associate or Full) in cancer research with a potential synergy w/ dept. members. Plz RT! recruit.ucdavis.edu/JPF06905
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The most highly cited paper each year in all of cancer research just got published from @AmericanCancer in @CACancerJournal CANCER STATISTICS 2025 The cancer mortality rate continued to decline in the 🇺🇸 thanks to earlier detection & better treatments. @OncoAlert @AhJemal
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🧵1/ Excited to share our latest review on how organoid technology is transforming pancreatic cancer research, published in Experimental & Molecular Medicine. Here's a breakdown of the key points. nature.com/articles/s12276-0…

Advancing pancreatic cancer research and therapeutics: the transformative role of organoid techno...

Experimental & Molecular Medicine - Pancreatic cancer is a challenging disease to study and treat. This article discusses how researchers have developed pancreatic organoids to better study...

nature.com
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Exciting study by Amanda Andersson Rolf et al: In vitro expansion of a human fetal #pancreas #stemcell that generates all three pancreatic cell lineages”. cell.com/cell/fulltext/S0092… 1/

Long-term in vitro expansion of a human fetal pancreas stem cell that generates all three pancrea...

Identification of an LGR5 as a marker for a tripotent stem/progenitor cell of the human fetal pancreas. Organoids derived from single LGR5+ cells are capable of long-term expansion in vitro and...

cell.com
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Pancreatic Cancer Awareness Month: Why We Wear Purple This November cihwang.wordpress.com/2024/1…
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Arrived @cshl for the mechanisms/models of cancer meeting. Has been 6yrs since I left. Time flies.
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Watching students grow academically has been one of the most gratifying aspects of being a faculty member in academia. @HwangLab Wishing you @Xu_Reno @sarahhwangg_ all the best on your future. Celebrating the Commencement of Our First PhD Graduates. cihwang.wordpress.com/2024/0…
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Drs. Reno Xu @Xu_Reno and Sarah Wang @sarahhwangg_ , two newly minted PhDs @hwanglab. Congrats! cihwang.wordpress.com/2024/0…
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6 Undergraduate researchers @HwangLab presented their posters at 35th Annual Undergraduate Research, Scholarship, and Creative Activities (URSCA) Conference. @ucdavis @UcdUrc. Great job everyone! Proud of you all.
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Whole genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures in pancreatic cancer.: iScience cell.com/iscience/fulltext/S…

Whole-genome bisulfite sequencing identifies stage- and subtype-specific DNA methylation signatures...

Genomics; Epigenetics; Cancer systems biology; Cancer

cell.com
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My grad student's manuscript (@sarahhwangg_ ) has been officially accepted in iScience. We used whole genome bisulfite sequencing to profile DNA methylation in PDAC patient-derived organoids, identifying stage- and subtype-specific signatures. stay tuned.
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Pancreatic ductal adenocarcinoma (PDAC) may have met its match! 🥊 After years of research at CSHL, we're targeting the Engrail-1 protein. Science 1, PDAC 0. #pancreaticcancer cshl.edu/pancreatic-cancer-h…

Pancreatic cancer hijacks a brain-building protein | Cold Spring Harbor Laboratory

Scientists at Cold Spring Harbor Laboratory (CSHL) and the University of California, Davis have reached a new breakthrough in pancreatic cancer research—eight years in the making. It could help slow...

cshl.edu
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Our research has been featured in @ucd @ucdavisbiology. Great job @Xu_Reno biology.ucdavis.edu/news/sea…
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