@HoodlessLab

Developmental gene networks | single-cell analyses | transcription factor and epigenetic mechanisms 🧬🧫🔬 @UBC @BCCancer

 Vancouver, BC, Canada
bccrc.ca/dept/tfl/labs/hoodless-lab
Joined November 2019
  • Tweets34
  • Following92
  • Followers237
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SEPTEMBER ISSUE | REVIEW Fetal liver development and implications for liver disease pathogenesis by @HoodlessLab & colleagues nature.com/articles/s41575-0… Figure shows the assembly of the mouse liver
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🎉 Excited to share the latest paper from the Hoodless lab by postdoc @BettinaMF in @NAR_Open, which explores SOX9 activity in the chromatin landscape upon endothelial-to-mesenchymal transition 🧬🧫academic.oup.com/nar/advance…

SOX9 reprograms endothelial cells by altering the chromatin landscape

Abstract. The transcription factor SOX9 is activated at the onset of endothelial-to-mesenchymal transition (EndMT) during embryonic development and in path

academic.oup.com
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The next @CEEHRC seminar is this Friday Mar. 25th! Dr. Pamela Hoodless @HoodlessLab and Bettina Fuglerud @BettinaMF from BC Cancer will be presenting! Head to the @CEEHRC site for more info & registration: bit.ly/3D0jtsy #ThisIsEpigenetics
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Finishing up your PhD, MD, a postdoc or already an early stage faculty member and from a historically underrepresented group in academia? Here is an excellent opportunity for #DEI scholars! 👩🏾‍🔬👩🏾‍🏫
American Association for Anatomy@AnatomyOrg
21 Oct 2021
Introducing the Anatomy Scholars Program! This program aims to support retention of URMs in STEM in academia. Scholars will participate in a two-year program of #professionaldevelopment activities. Apply by Dec. 2: bit.ly/3DTTrq7 #AnatDEI #STEMDEI #anatomy #AnatEd
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New review! 🎉 Hoodless lab alumna @stephi_campbell’s WFH project is out! 🎉 You think signaling pathways and transcriptional regulators involved in liver development/cancer are cool? Wondering what’s new? Read this excellent review to get an overview!
Development@Dev_journal
7 Sep 2021
Signalling pathways and transcriptional regulators orchestrating liver development and cancer In their Review, @stephi_campbell, @HoodlessLab and colleagues discuss liver development, cancer and the use of hepatic tissue engineering models journals.biologists.com/dev/…
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Thanks for the feature @ScienceVancity !
Science in Vancouver
@ScienceVancity
10 Nov 2020
The @HoodlessLab at @BCCancer has released a major paper in @CellCellPress analyzing transcriptional data from 45,334 cells to create a comprehensive atlas of liver formation at single-cell resolution. bit.ly/32kCNQc
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Excited to share the latest paper from the Hoodless Lab by PhD student Jeremy Lotto published in @CellCellPress,which uses single-cell transcriptomics to delineate the earliest specification events in liver endothelial,mesenchymal + parenchymal development rb.gy/ylkacd
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This work was only possible thanks to support from @CIHR_IRSC, @NSERC_CRSNG, @InnovationCA, @GenomeBC, @NIH, @10xGenomics, @sloan_kettering, BC Knowledge Development Fund and our great collaborators @dana_peer and lab, @emarieb_E and the Hadjantonakis Lab 👏
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Up next at #TMM2020 in Plenary II: Self-organizing Models of Tissue Function & Disease chaired by @HoodlessLab.
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Check out the latest work of our talented postdoc 👩🏻‍🔬 @BettinaMF on SOX9 pioneer chromatin functions in EndMT in collaboration with @UniOslo funded by a mobility grant from @RCN_Norway biorxiv.org/content/10.1101/…

SOX9 is sufficient to drive endothelial cells towards a mesenchymal fate by altering the chromatin...

The transcription factor SOX9 is expressed in multiple tissues during embryogenesis and directs developmental processes. SOX9 is activated upon epithelial-to-mesenchymal transition (EMT) and the...

biorxiv.org
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#2020SDB is Going Virtual! July 9-12 for talks; July 13-16 for posters! Lower registration & abstract submission fees! Forms are temporarily closed for updates. Those who have already paid will be refunded the difference. New Abstract Deadline: May 6, 2020 sdbonline.org/2020mtg
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Impressive lab update from @BettinaMF today. Forget ChIP-seq, she has beautiful CUT&RUN data!
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Keeping our tradition of Friday morning coffee breaks ☕️ today in the funny hat edition!
Dr. Stephanie Campbell@stephi_campbell
3 Apr 2020
Meanwhile in the @HoodlessLab...
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We are very proud of our former Research Associate Dr. Juan Hou who is leading the epithelial team @STEMCELLTech and accelerating #COVID19 research!
STEMCELL Technologies
@STEMCELLTech
24 Mar 2020
We are proud to work with scientists globally to support #COVID19 research! Our tissue culture systems were used by researchers at China's CDC to grow airway cells that successfully propagated the novel #coronavirus, accelerating vaccine development. bwnews.pr/2UMyM2v
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Exciting news from the Hoodless Lab! 👨🏼‍🔬 Jeremy Lotto’s 1st first author paper is now available as a preprint! thenode.biologists.com/febru… Learn about how #scRNAseq reveals cell emergence in #liver #development @10xGenomics @ScienceVancity @the_Node

February in preprints - the Node

Welcome to our monthly trawl for developmental biology (and related) preprints.  February's haul features blooming orchids, regenerating lungfish and

thenode.biologists.com
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EXCITING NEWS! Registration now open for our 4th ANNUAL MAY SYMPOSIUM! Featuring Dr. Harry Atkins, Dr. Jeff Biernaski, Dr. Ly Vu, Dr. Massimiliano Paganelli and MORE! Register here: bit.ly/39hw5Mp !
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Gordon Keller taught us all about heart and liver development yesterday. These are our favourite organs in the @HoodlessLab too! It was also great to get an update on the impressive work from former @UBC PhD @blairkgage 🌟
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Hoodless Lab retweeted
DMM Journal@DMM_Journal
11 Feb 2020
It's @WomenScienceDay, and we're celebrating Dr Pamela Hoodless @hoodlesslab, our #devbio and #stemcell editor: bccrc.ca/dept/tfl/labs/hoodl…
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Liver #organoids are growing in the @HoodlessLab! 🧫🔬🍩
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Fun in the @HoodlessLab today dissecting 40+ embryonic livers. What is GFP labeling?
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