Joined July 2023
semaili hiba retweeted
Immunohistochemical Approach to the Classification and Diagnosis of Ovarian Tumors Primary ovarian tumors are broadly classified into three major categories: epithelial tumors, germ cell tumors, and sex cord-stromal tumors. The selection of immunohistochemical markers for the classification of ovarian tumors may include: Epithelial tumor markers: CK, EMA, PAX8, CK7, CK20, etc. Germ cell tumor markers: SALL4, PLAP, OCT4, etc. Sex cord-stromal tumor markers: α-inhibin, calretinin, SF-1, etc. Hormone receptor markers: ER and PR.
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70 y.o. M, orchiectomy. What is the diagnosis? @MGBpathology @MGHPathology
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Thyroid Follicular Cell-Derived Neoplasms: (Basic Facts for Residents) Low risk and malignant neoplasms; NIFTP, FT-UMP, WDT-UMP, hyalinizing trabecular tumor, FVPTC, IEFVPTC, Differentiated HGTC, PDTC #ThyroidTumorsUpdates #BasicFactsForResidents #MakeSurgiPathEasy
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semaili hiba retweeted
#GUpath: nested pattern invasive urothelial carcinoma? 😨 NOPE! just normal VonBrunn nests in the upper urothelial tract of this kidney😅
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Their presence can be subtle 🔬 Urothelial carcinoma with trophoblastic differentiation. Note the syncytiotrophoblasts occasionally surround (cap) the urothelial cells and are thinned out. See IHC in comment. #GUPath
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Atypical Mitosis Some familiar objects in abnormally dividing cells #histology #pathology #pathArt #cancer (📷by #pathologists tagged below)
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A #dermpath classic. Can you make the diagnosis from one pic? (IRL, must fit with clinical info of course) Answer: youtube.com/watch?v=xWEmPZw9… #pathology #pathologists #pathTwitter #dermatology #dermatologia #dermtwitter
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WHO classification must specify PTC histology, e.g., classic → "classic papillary microcarcinoma" “Papillary microcarcinoma" 🚫distinct histologic subtype #PathResidents #PathTwitter #EndoPath #ENTPath ✅Tall cell papillary microcarcinoma Tall cell height🟰2⃣to3⃣✖️width "tall cell features" if < 30% tumor cells
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Classic hibernoma is >70% brown fat with mix of 1⃣mature univacuolated adipocytes 2⃣multivacuolated large adipocytes with normochromic central nuclei 3⃣large polygonal cells with abundant granular eosinophilic cytoplasm and central normochromic nuclei Lipoma-like hibernomas contain more mature fat Essential per WHO: multivacuolated cells with normochromic central nuclei (2) #BSTPath #PathTwitter #PathResidents 📽️@JMGardnerMD youtu.be/cXpecEdq8Tw?si=JtXN… ✅2⃣
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🍕 Pizza Day 🍕 Sometimes cells remind me of food. This is a fine needle aspirate containing epithelial cells from an adenocarcinoma in the lung. i♡histo 📷 by @jlndlc #histology #science #pathology #anatomy
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I (finally) completed my CNS tumor notes for "Kurt's Notes" (kurtsnotes.net/)! 🧠🧠🧠🧠🧠🧠🧠🧠🧠🧠 Full notes here: schaberg.faculty.ucdavis.edu… 🧠🧠🧠🧠🧠🧠🧠🧠🧠🧠
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I just updated my Thyroid Cytology notes on my teaching website, "Kurt's Notes" (kurtsnotes.net/) to incorporate the newest Bethesda system. 🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬 Full notes available here: schaberg.faculty.ucdavis.edu…
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What is this skin nodule? (Hint: it's 2 for 1 special! 😉) Answer: kikoxp.com/posts/11029. #pathology #pathologists #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter
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This image of colonic strongyloidiasis is courtesy of Dr. Dale Snover, who has retired from the University of Minnesota.
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The many cells of Hodgkin's lymphoma: 1️⃣Reed-Sternberg cell 🦉 2️⃣ Hodgkin cells 3️⃣Lacunar cells 4️⃣Mixed inflammatory background #pathtwitter #pathology #Hodgkinslymphoma
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🔬Poorly cohesive gastric carcinoma : ✔️Aggressive form of gastric cancer characterized by early spread ✔️Composed of neoplastic cells that are isolated or arranged in small aggregates without well formed glands ✔️lmmunohistochemical stain(AE1/AE3): highlight neoplastic cells
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Chromophobe Renal Cell Carcinoma demonstrating classic features: 🔬'plant cell wall-like' membranes 🔬peri-nuclear halos 🔬bi-nucleation AND 🔬regions w/numerous micro-calcifications Ca++ may be seen in 30-50% of Chromophobe RCC (PMID: 18813125, 21602658) #kidneycancer #gupath
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Nice "hallmark cells." Flow cytometry is negative in almost 20% of anaplastic large cell lymphoma (ALCL) including this one. #hemepath
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Round & blue with mitoses, too. Hard to diagnose from this pic? (hint - it's benign!) Digital slide: kikoxp.com/posts/13669 Answer: kikoxp.com/posts/4951 Videos: kikoxp.com/posts/4318 & kikoxp.com/posts/4380 #pathology #pathTwitter #dermpath #dermatology #dermtwitter
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