semaili hiba retweeted
Immunohistochemical Approach to the Classification and Diagnosis of Ovarian Tumors
Primary ovarian tumors are broadly classified into three major categories: epithelial tumors, germ cell tumors, and sex cord-stromal tumors.
The selection of immunohistochemical markers for the classification of ovarian tumors may include:
Epithelial tumor markers: CK, EMA, PAX8, CK7, CK20, etc.
Germ cell tumor markers: SALL4, PLAP, OCT4, etc.
Sex cord-stromal tumor markers: α-inhibin, calretinin, SF-1, etc.
Hormone receptor markers: ER and PR.
🤖 Made with AI
semaili hiba retweeted
70 y.o. M, orchiectomy. What is the diagnosis?
@MGBpathology @MGHPathology
semaili hiba retweeted
Thyroid Follicular Cell-Derived Neoplasms:
(Basic Facts for Residents)
Low risk and malignant neoplasms; NIFTP, FT-UMP, WDT-UMP, hyalinizing trabecular tumor, FVPTC, IEFVPTC, Differentiated HGTC, PDTC
#ThyroidTumorsUpdates
#BasicFactsForResidents
#MakeSurgiPathEasy
semaili hiba retweeted
#GUpath:
nested pattern invasive urothelial carcinoma? 😨
NOPE! just normal VonBrunn nests in the upper urothelial tract of this kidney😅
semaili hiba retweeted
Their presence can be subtle 🔬
Urothelial carcinoma with trophoblastic differentiation.
Note the syncytiotrophoblasts occasionally surround (cap) the urothelial cells and are thinned out.
See IHC in comment. #GUPath
semaili hiba retweeted
Atypical Mitosis
Some familiar objects in abnormally dividing cells
#histology #pathology #pathArt #cancer
(📷by #pathologists tagged below)
semaili hiba retweeted
A #dermpath classic. Can you make the diagnosis from one pic?
(IRL, must fit with clinical info of course)
Answer: youtube.com/watch?v=xWEmPZw9…
#pathology #pathologists #pathTwitter #dermatology #dermatologia #dermtwitter
semaili hiba retweeted
WHO classification must specify PTC histology, e.g., classic → "classic papillary microcarcinoma"
“Papillary microcarcinoma" 🚫distinct histologic subtype
#PathResidents #PathTwitter #EndoPath #ENTPath
✅Tall cell papillary microcarcinoma
Tall cell height🟰2⃣to3⃣✖️width
"tall cell features" if < 30% tumor cells
semaili hiba retweeted
Classic hibernoma is >70% brown fat with mix of
1⃣mature univacuolated adipocytes
2⃣multivacuolated large adipocytes with normochromic central nuclei
3⃣large polygonal cells with abundant granular eosinophilic cytoplasm and central normochromic nuclei
Lipoma-like hibernomas contain more mature fat
Essential per WHO: multivacuolated cells with normochromic central nuclei (2)
#BSTPath #PathTwitter #PathResidents
📽️@JMGardnerMD
youtu.be/cXpecEdq8Tw?si=JtXN…
✅2⃣
semaili hiba retweeted
🍕 Pizza Day 🍕
Sometimes cells remind me of food.
This is a fine needle aspirate containing epithelial cells from an adenocarcinoma in the lung.
i♡histo
📷 by @jlndlc
#histology #science #pathology #anatomy
semaili hiba retweeted
I (finally) completed my CNS tumor notes for "Kurt's Notes" (kurtsnotes.net/)!
🧠🧠🧠🧠🧠🧠🧠🧠🧠🧠
Full notes here: schaberg.faculty.ucdavis.edu…
🧠🧠🧠🧠🧠🧠🧠🧠🧠🧠
semaili hiba retweeted
I just updated my Thyroid Cytology notes on my teaching website, "Kurt's Notes" (kurtsnotes.net/) to incorporate the newest Bethesda system.
🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬🔬
Full notes available here: schaberg.faculty.ucdavis.edu…
semaili hiba retweeted
What is this skin nodule? (Hint: it's 2 for 1 special! 😉) Answer: kikoxp.com/posts/11029. #pathology #pathologists #pathTwitter #dermpath #dermatology #dermatologia #dermtwitter
semaili hiba retweeted
This image of colonic strongyloidiasis is courtesy of Dr. Dale Snover, who has retired from the University of Minnesota.
semaili hiba retweeted
The many cells of Hodgkin's lymphoma:
1️⃣Reed-Sternberg cell 🦉
2️⃣ Hodgkin cells
3️⃣Lacunar cells
4️⃣Mixed inflammatory background
#pathtwitter #pathology #Hodgkinslymphoma

ALT 1️⃣RS cell:large size bilobated nucleus prominent eosinophilic nucleolus 2️⃣Hodgkin cell: single round nucleus with prominent eosinophilic nucleolus 3️⃣Lacunar cells: pale retracted cytoplasm creating lacunae- like space 4️⃣ Mixed inflammatory background:small lymphocytes, neutrophils, eosinophils, histiocytes, plasma cells.
🔬Poorly cohesive gastric carcinoma :
✔️Aggressive form of gastric cancer characterized by early spread
✔️Composed of neoplastic cells that are isolated or arranged in small aggregates without well formed glands
✔️lmmunohistochemical stain(AE1/AE3): highlight neoplastic cells
semaili hiba retweeted
Chromophobe Renal Cell Carcinoma demonstrating classic features:
🔬'plant cell wall-like' membranes
🔬peri-nuclear halos
🔬bi-nucleation
AND
🔬regions w/numerous micro-calcifications
Ca++ may be seen in 30-50% of Chromophobe RCC
(PMID: 18813125, 21602658)
#kidneycancer #gupath
semaili hiba retweeted
Nice "hallmark cells." Flow cytometry is negative in almost 20% of anaplastic large cell lymphoma (ALCL) including this one. #hemepath
semaili hiba retweeted
Round & blue with mitoses, too.
Hard to diagnose from this pic? (hint - it's benign!)
Digital slide: kikoxp.com/posts/13669
Answer: kikoxp.com/posts/4951
Videos: kikoxp.com/posts/4318 & kikoxp.com/posts/4380
#pathology #pathTwitter #dermpath #dermatology #dermtwitter




















































