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📢 I am happy to announce that our joint manuscript with @Anna_Wilhelmson and @Bo_Porse is out in @NatureComms. We show that TET2 loss aggravates CEBPA-mutated AML by rebalancing GATA2 levels. 1/ rdcu.be/dnI4F
We propose a model in which elevated levels of CEBPA p30 recruit more TET2 to the GATA2 enhancer resulting in higher, suboptimal GATA2 expression. Loss of TET2 reduces GATA2 expression and thereby gives the leukemic cells a competitive advantage. 9/
Many thanks to co-first author @Anna_Wilhelmson and co-last authors @Bo_Porse and @floriangrebien for the successful collaboration over the last years, and to all co-authors! @VetmeduniVienna @StAnna_CCRI /10
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
Fantastic Talk by @SelinaTroester about her PhD work at #YERM23 #EHA23. Very #proudPI #grebienlab. @young_eha @VetmeduniVienna @StAnna_CCRI
Exciting data presented by @SelinaTroester from @florian_grebien lab on how NUP98-KDM5A maintain leukemia. Beautiful story! #YERM23 #EHA2023 @young_eha
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
Arrived at #EHA2023 ! I am very excited to give a talk today at the #YoungEHA Research Meeting. If you are interested in our newest findings about NUP98-fusion leukemia stop by at session 4 - transcription control.
@young_eha @EHA_Hematology
Live from #EHA2023 in Frankfurt 🇩🇪 looking forward to all the good science! 👩🔬🔬 @SelinaTroester
Day 1 kick off #YoungEHA @young_eha @EHA_Hematology
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
🚨JOB ALERT 🚨
We are recruiting an Assistant Professor (Tenure Track) in the field of "#Molecular #Cell #Biology in #Biomedicine" @VetmeduniVienna
Details 👉 vetmeduni.ac.at/fileadmin/v/…
Apply until 03.05.2023!
Please RT #sciencetwitter #STEM
(📷Niko Havranek/Vetmeduni)
📢👩🔬👨🔬 The #grebienlab is hiring a research technician to support the lab and work on exciting projects in #cancer research! 🧬🧫🔬🥼🧪Find more information on grebienlab.com or fwf.ac.at/de/service/fwf-job… Please RT
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
Original research article -
The authors used this protocol in:
nature.com/articles/s41375-0…
@LeukemiaJnl @SpringerNature @florian_grebien @HeyesElizabeth
Please like, comment and follow our page for regular updates. Again, congratulations for the awesome work!!
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
Check out our new protocol "Arrayed #CRISPR /#Cas9 #Screening for the Functional Validation of #Cancer #Genetic Dependencies".
bit.ly/3YXV6GE
Awesome work by -
@ProiettiL_ @HeyesElizabeth @SelinaTroester @florian_grebien @VetmeduniVienna
#grebienlab #oncoproteins
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
📢👩🎓👨🎓The #grebienlab is hiring again! We look for 1 #postdoc and 1 #PhD #student to help us unravel molecular mechanisms of #fusion #oncoproteins in #cancer through functional genomics, imaging and biochemistry. 🧬🧫💊💻 @VetmeduniVienna Please RT!
👉 grebienlab.com/ – at Graz, Austria
Elizabeth Heyes 🇺🇦🇪🇺 retweeted
There is one week left to apply for a master's position in our lab! 🧬Deadline --> 31.10.2022
‼️ We are looking for a motivated master's student to work on a thesis about epigenetics in fusion oncoprotein-driven leukemia. Please RT and spread the word!🌈
For more info about the position, application & our lab visit our website
➡️ grebienlab.com/master-studen…












