@Hartrampf_Lab

Student-run account of the Hartrampf Lab at @UZH_chemistry @NinaHartrampf. Chemical biology and flow chemistry, with a focus on peptides and proteins 🧫🧪🥼

 Zurich, Suisse
hartrampf-lab.com
Joined September 2021
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  • Following101
  • Followers267
3Media
✨ From solving clues on a fox trail through Zurich to enjoying a fondue together, we had a great holiday celebration. Wishing you all happy holidays and a fantastic start to 2025! 🎄❄️
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Our versatile SynTag will become a valuable addition to the chemical protein synthesis toolbox to handle difficult and insoluble sequences: Exciting new findings published in JACS: pubs.acs.org/doi/10.1021/jac… by the @NinaHartrampf Lab @UZH_Chemistry
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Excited to see our Synthesis Tag (SynTag) for the chemical synthesis of aggregating peptides and proteins out in @J_A_C_S!! 🥳 pubs.acs.org/doi/10.1021/jac… Congratulation to first authors Héloïse Bürgisser and @elysetwilliams and everyone else involved @UZH_Chemistry @UWMadScience

A Versatile “Synthesis Tag” (SynTag) for the Chemical Synthesis of Aggregating Peptides and Proteins

Abstract. Solid-phase peptide synthesis (SPPS) and native chemical ligation (NCL) are powerful methods for obtaining peptides and proteins that are otherwi

pubs.acs.org
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Congratulations to Kevin, first PhD of the Hartrampf lab, for his brilliant defense today! 🎓 We are so proud of you, and can’t wait to see how far you go🌟
Nina Hartrampf@NinaHartrampf4 Dec 2024
🥳 Today we celebrated the PhD defense of our first PhD student Kevin Schiefelbein @UZH_Chemistry 🤩 It was so great to see the full lasso peptide story coming together! Congratulations Kevin! #proudPI ✨ Thank you also to committee members @KarlGademann and @piel_lab 🙏
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Dear @UZH_Chemistry cake lovers, the Great Chemistry Bake Off 2024 will take place on December 17. Save the date and come taste some delicious cakes created by our chemists! :-) @NinaHartrampf @Hartrampf_Lab @JuricekLab @UZH_Science @UZH_en @UZH_ch
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Hartrampf Lab retweeted
SNE ChemBio@SNE_ChemBio25 Nov 2024
Don’t miss tomorrow's 🆓 in-person #chembio seminar by Prof. Dr. Nina Hartrampf (@NinaHartrampf, @UZH_Chemistry) @EPFL_en: 👉 "New Methods for the Chemical Synthesis of Post-Translationally Modified Peptides and Proteins" ⏱️🇨🇭16:15 › 17:15 📢 bit.ly/3MOjVjy @Beatfierz
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Shoutout to the @UZH_Chemistry members, the Great Chemistry Bake Off will take place on Dec 17! Chemists from @UZH_Science will show their amazing baking skills :-) @NinaHartrampf @Hartrampf_Lab @JuricekLab @UZH_ch
Karl Gademann@KarlGademann23 Oct 2024
Coming up @UZH_en, the great chemistry bake off!
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📣📣 We are hiring! Find out more about our open PhD position below ⬇️
Nina Hartrampf@NinaHartrampf11 Oct 2024
Are you looking for a PhD position in peptide synthesis, automation, and computational analysis? 🧪 💊💻 We have an open position for a collaborative PhD thesis (with Novo Nordisk). For more details, please see: jobs.uzh.ch/job-vacancies/ph… ⏰ Application deadline = November 15
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Congratulation to Nina @Hartrampf_Lab @UZH_Chemistry 👏👏👏
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Congratulation to Kevin 👏👏, Bálint 👏and Claire 👏from the @Hartrampf_Lab @UZH_Chemistry for receiving best presentation awards
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Starting the academic year with fresh ideas💡and great company 👥 at our annual research retreat! 🏞️
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Thank you for awarding me the „RSC CEM Emerging Investigator in Protein and Peptide Science“! 🙏 I look forward to (virtually) joining the symposium on Friday @RSC_PPSG ☺️
RSC Protein and Peptide Science Group@RSC_PPSG2 Sep 2024
🏆 Congrats to Prof. Nina Hartrampf on winning the RSC CEM Emerging Investigator in Protein and Peptide Science from the whole of the PPSG committee and community! Thank you for you contributions to the field.
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Two days of Peptide Therapeutics Forum 2024 come to an end 😌 Thanks to everyone from ⁦@UZH_Chemistry for joining 🙏 And congratulations on the awards Kevin and Bálint! 🥳 ⁦@Hartrampf_Lab⁩ ⁦@KarlGademann⁩
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Thank you for highlighting our work on the chemoenzymatic synthesis of modified lasso peptides on the covers of @J_A_C_S! 🤩 @Hartrampf_Lab @UZH_ch #peptides
J. Am. Chem. Soc.@J_A_C_S1 Jul 2024
From this week's covers: Sidechain- and backbone-modified lasso peptides were produced via a chemoenzymatic approach, offering a promising framework for designing peptide-based drugs. @UZH_Chemistry @NinaHartrampf Learn more ➡️ go.acs.org/a2g
JACS Front Cover Volume 146, Issue 25 Image depicting the article "Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides"

ALT JACS Front Cover Volume 146, Issue 25 Image depicting the article "Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides"

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Congratulations to all awardees, especially Bálint @Hartrampf_Lab 👏🤩
UZH Chemistry@UZH_Chemistry4 Jul 2024
Congratulation to Dorothea @dorothea_ko from the @RiveraChemLab, Marc @Marc_Lennon from the @NevadoLab, Anton @AntonNatter from the @lab_adl, Pauline @pauline_pfister from the @JuricekLab and Balint from the @NinaHartrampf on winning an UZH candoc grant 👏👏👏👏👏
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The PhD students of the @UZH_Chemistry department did a fantastic job organizing this year’s ChemPosium - thank you so much! 🙏 In addition to attending the conference, our group also had the opportunity to spend some time with @MortenMeldal in the afternoon. 🤩
Dorothea Kossmann@dorothea_ko28 Jun 2024
Thrilled by how this year’s #ChemPosium turned out! PhD students of @UZH_Chemistry delivered fantastic talks and posters. Nobel Laureate Prof. @MortenMeldal’s keynote speech was incredibly motivating for us young researchers. Huge thanks to @youngSCS1 for their support!
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Our chemoenzymatic synthesis of the lasso peptide Microcin J25 is out now in @J_A_C_S! We used flow-SPPS to synthesize several sidechain- and backbone-modified precursor peptides and demonstrated their in vitro transformation. pubs.acs.org/doi/10.1021/jac… @UZH_Chemistry @Hartrampf_Lab

Merging Flow Synthesis and Enzymatic Maturation to Expand the Chemical Space of Lasso Peptides

Abstract. Many peptidic natural products, such as lasso peptides, cyclic peptides, and cyclotides, are conformationally constrained and show biological sta

pubs.acs.org
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Our chemical synthesis of PTM-modified MYC peptides and their interactions with the tumor suppressor Bin1 is online @ChemicalScience. Congratulations @elysetwilliams, @rebeccabev5, @ZerbeOliver, and everyone else involved! 🎉 pubs.rsc.org/en/content/arti… #MyFirstChemSci
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Thank you for inviting me over to the Midwest and for hosting me at @UMNews, @DanHarki! I had a fantastic time at your department, and a very nice dinner with you and @nanorunner1 🙏 I am especially grateful for my student host Laura who accompanied me during the past two days ☺️
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Submit your abstract to give a presentation at the Peptide Therapeutics Forum 2024 in Basel! 💻📬 Looking forward to seeing you there in August.
Swiss Chemical Society@SwissChemistry15 Apr 2024
🔔Last chance to apply for a contributed talk at the Peptide Therapeutics Forum 2024 Don't miss this opportunity! 🗓️Deadline for abstract submission is April 21 More info: ptf24.scg.ch #ptf24 #scs #switzerland #peptides #medchem #symposia #chemistry #chembio
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