@HarrisonBesser

MD/PhD Candidate @Stanford in the Khosla Lab | Former @HarvardCCB

 Stanford, CA
Joined June 2021
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  • Following99
  • Followers46
Harrison Besser retweeted
Stanford Medicine
@StanfordMed9 Oct 2025
To improve the diagnosis and monitoring of celiac disease — and to find pathways for treatment — longtime collaborators are testing the use of a fluorescent compound to track and illuminate a celiac disease-triggering molecule in patients. stan.md/42HVrk3
A Stanford Medicine clinician and scientist collaborate on new methods to diagnose, treat and track celiac disease

ALT A Stanford Medicine clinician and scientist collaborate on new methods to diagnose, treat and track celiac disease

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Gita Abhiraman, graduating from the Stanford School of Medicine, was inspired to pursue a career in immunotherapy after an early treatment saved her mother’s life. Now, she’s focused on advancing treatments that improve patient outcomes. #StanfordMed2025 med.stanford.edu/news/insigh…

Immunotherapy cured her mother’s cancer, then drew her into medicine

When Gita Abhiraman was a child, an early form of immunotherapy saved her mother’s life. She has dedicated her career to finding innovative treatments that could help others.

med.stanford.edu
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Excited to share this work from the Garcia Lab out today in @NatureComms! We engineer "cytokine adaptors", molecular switches that simultaneously block a target cytokine while inducing local activation of alternative cytokine receptors. rdcu.be/ec7GS
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Excited to share a review I recently wrote with my advisor, Chaitan Khosla (@KhoslaLab @Stanford_ChEMH), about the molecular basis of celiac disease and how teams of translational scientists and clinicians are seeking to treat it! doi.org/10.1016/j.tips.2023.…
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Harrison Besser retweeted
J. Am. Chem. Soc.@J_A_C_S18 Aug 2023
Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP-1 Pathway | Journal of the American Chemical Society ⁦@Stanford_ChEMH @Stanford @StanfordUChem #Lysosomal #LYTAC #Degradation #CellSurface #Proteins #LRPPathway ⁩ pubs.acs.org/doi/10.1021/jac…

Targeted Lysosomal Degradation of Secreted and Cell Surface Proteins through the LRP‑1 Pathway

Abstract. Protein dysregulation has been characterized as the cause of pathogenesis in many different diseases. For proteins lacking easily druggable pocke

pubs.acs.org
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Harrison Besser retweeted
Cell Reports@CellReports20 Jun 2023
A structural blueprint for interleukin-21 signal modulation dlvr.it/SqymnY

A structural blueprint for interleukin-21 signal modulation

Abhiraman et al. solve structures of the IL-21 receptor complex by X-ray crystallography and cryo-electron microscopy. Structure-based engineering of IL-21 leads to variants that modulate pS6,...

cell.com
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Harrison Besser retweeted
Theodora@theobruun22 Mar 2023
Better late than never! Happy to share this work alongside my co-authors including @StevenTangPhD @grahamserwin out now @JBC. Initially, we were interested in studying the gp41 pocket of HIV-1, a highly conserved drug/vaccine target..🧵(1/5) doi.org/10.1016/j.jbc.2023.1…
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Online now! LRP-1 links post-translational modifications to efficient presentation of celiac disease-specific T cell antigens dlvr.it/SgQx9w #chembiol
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