Great to see this work out, Aruj Dhyani. Great to see #ADC target expression in #BTC, supports several ongoing clinical trials. @MSKCancerCenter @MSK_DeptOfMed
aacrjournals.org/clincancerr…
James J. Harding, MD retweeted
An absolute honour @HardingJJMD 😊
🗞️Just published!
Our latest review on #targeted therapies in #BiliaryMalignancies in @JHepatology
sciencedirect.com/science/ar…
Replying to @DrAngelaLamarca
@DrAngelaLamarca and Do Youn Oh!
@HardingJJMD enjoyed writing with you on #personalized #therapy #biliarytractcancers. Promise, limitations, and solutions!
@MSK_DeptOfMed @MSKCancerCenter @JHepatology
sciencedirect.com/science/ar…
James J. Harding, MD retweeted
Replying to @DrAngelaLamarca
@DrAngelaLamarca and Do Youn Oh!
@HardingJJMD enjoyed writing with you on #personalized #therapy #biliarytractcancers. Promise, limitations, and solutions!
@MSK_DeptOfMed @MSKCancerCenter @JHepatology
sciencedirect.com/science/ar…
Congratulations @CowzerDarren. Great deep dive #biliarytractcancer #genomics outcomes and resistance! @MSK_DeptOfMed @MSKCancerCenter @MskccCMO @DSolit @GABOUALFA @EileenMOReilly
Now online: Molecular and Clinical Determinants of Targeted Therapy Treatment in Biliary Tract Cancer doi.org/10.1158/1078-0432.CC…
James J. Harding, MD retweeted
New findings presented at #ASCO26 suggest a new approach could help slow the growth of intermediate-stage liver cancer.
An international phase 3 clinical trial led by MSK's Dr. Ghassan K. Abou-Alfa (@GABOUALFA) found that adding dual immunotherapy to TACE significantly increased progression-free survival for people with hepatocellular carcinoma (HCC).
“By combining dual immunotherapy with TACE, we give patients a better chance of living longer while preserving a healthy, working liver.”
Learn more: bit.ly/4x7vt7o
#ASCO2026 @MSKCancerCenter Advanced Fellow @OrlaFitz10 2 fantastic posters, #HER2 #RAS #BTC! Advanced Fellow Aruj Dhyani #YIA #ADC #BTC Assistant Attending @rohit_thum #MTAP #NET #BTC #PDAC. Glad to mentor, but grateful for what you teach me too!
James J. Harding, MD retweeted
Proud to see 18 MSK staff recognized as 2026 Conquer Cancer Grants & Awards recipients ahead of #ASCO26. Congratulations to this outstanding group helping advance the future of cancer research and care. 👏
We're thrilled to officially announce the 2026 class of Conquer Cancer Grants and Awards recipients! 🔬 These grants empower the next generation of physician-scientists to turn innovative ideas into clinical breakthroughs. Congratulations to the new class—see you in Chicago for #ASCO26!
Full list of recipients here: bit.ly/4x0qpBF
#ResearchConquersCancer #ConquerCancer @ASCO
⏳ Still time to join #ESMOTATAsia26
Be part of ESMO Targeted Anticancer Therapies Asia 2026, a key Asia Pacific forum for cancer drug development.
👉 Register by 3 June and save: ow.ly/Xn2u50Z4Gzc
#ESMOMeetings
James J. Harding, MD retweeted
⚠️ New MSK research presented at #AACR26: A drug given “breakthrough designation” by @US_FDA may offer the best new option in many years for people facing #pancreaticcancer.
#Daraxonrasib targets mutations in the RAS gene, which helps control cell growth — these mutations send signals that fuel cancer cells. #KRAS is the most common of these mutations and drives over 90% of pancreatic cancer, which is projected to be the second most deadly cancer in the U.S. by 2030.
MSK gastrointestinal medical oncologist @EileenMOReilly led a phase 1/2 clinical trial of daraxonsarib as part of a larger multidisease trial led by thoracic medical oncologist Dr. @KCArbourMD. In Dr. O’Reilly’s trial, the patients with pancreatic cancer had not yet received any form of treatment.
“This drug is potentially going to be a landmark shift in how we treat pancreatic cancer,” says Dr. O'Reilly. “The ability to target RAS mutations that drive so much of pancreatic cancer is huge and has been missing from our treatments.”
Learn more about this research: bit.ly/4trr1xK @AACR
James J. Harding, MD retweeted
Great to present phase 1b data for DLL3 ADC ZL-1310 (zoci) in platinum-refractory neuroendocrine carcinomas at #AACR26. Phase 2 is ongoing and we are excited to develop this drug further for these difficult to treat populations. @ZaiLab_Global @MSKCancerCenter @MSK_DeptOfMed
Thank you @GABOUALFA, @MSK_DeptOfMed for many years of mentorship/support in #HPB cancers. Amazing to win this @theNCI #R01 award. @EileenMOReilly , @YJanjigianMD @DSolit @OlcaBasturk @MskccCMO @MSKBiostats @MSKCancerCenter
Congratulations @HardingJJMD on your #R01. @MSKCancerCenter @MSK_DeptOfMed and all colleagues are happy for you!
James J. Harding, MD retweeted
Congratulations @HardingJJMD on your #R01. @MSKCancerCenter @MSK_DeptOfMed and all colleagues are happy for you!
James J. Harding, MD retweeted
It was a great honor and delight for @MSKCancerCenter @MSK_DeptOfMed @GABOUALFA and @HardingJJMD to join this superb teaching effort. Thanks @oncodaily for the opportunity
𝗛𝗼𝘄 𝗜 𝗧𝗿𝗲𝗮𝘁 𝗚𝗮𝗹𝗹𝗯𝗹𝗮𝗱𝗱𝗲𝗿 𝗮𝗻𝗱 𝗕𝗶𝗹𝗲 𝗗𝘂𝗰𝘁 𝗖𝗮𝗻𝗰𝗲𝗿 𝗶𝗻 𝟮𝟬𝟮𝟲 | 𝗢𝗻𝗰𝗼𝗗𝗮𝗶𝗹𝘆 𝗩𝗶𝗿𝘁𝘂𝗮𝗹 𝗦𝘂𝗺𝗺𝗶𝘁
The Gallbladder and Bile Duct Cancer Summit 2026, organized by OncoDaily, brought together international experts to examine evolving clinical strategies and innovation shaping the management of gallbladder and biliary tract cancers.
During this session, Ghassan Abou-Alfa (@GABOUALFA), James J Harding (@HardingJJMD), Vinay Kumar Kapoor (@vkkapoor_india) and Thatcher Heumann (@HeumannThatcher) shared expert perspectives on contemporary systemic therapy for biliary tract cancers, the fundamental “Ten Commandments” guiding gallbladder cancer management, practical approaches to treating gallbladder cancer in clinical practice, and emerging HER2- and RAS-targeted therapies shaping the future of hepatobiliary oncology.💡
Join the live conversation: xitter.cf/i/broadcasts/1nKOLELlk…
#OncologySummit #GlobalOncology #CancerTreatment #OncoDaily #Oncology #Cancer #Health #Medicine #GallbladderCancer
Great Ride for #Liver #bileduct #cancer! Thank Chris Crane and Matt McMillan for joining The LIVE Riders! @Cycle4Survival @MSK_DeptOfMed @MSKCancerCenter.
Great work @OrlaFitz10 Glad to mentor you and happy you are part of our #HPB team @MSKCancerCenter, @MSK_DeptOfMed Excellent editorial on #HER2 directed therapy in #biliarytractcancer. aacrjournals.org/clincancerr…
Support #Liver and #BileDuctCancer Research! We're participating in @Cycle4Survival to raise money for rare cancer research at @MSKCancerCenter, and your support would mean so much to us. Make a 100% tax-deductible donation using the link. Thank you! secure2.convio.net/mskcc/sit…
James J. Harding, MD retweeted
Fantastic panel discussion on the future of #HCC therapy with @MarkYarchoan @DrElkhoueiry @HardingJJMD @DJPinato @JosephFranses #richardfinn
The near future is a “plateau” while we await the next breakthrough
@AnjanaPillaiMD @docamitgs @laurakulik1
#livertwitter
James J. Harding, MD retweeted
Radiologists play a critical role in assessing systemic therapy response in liver cancers; this requires a comprehensive approach beyond size changes to support personalized management. @VChernyakMD @taehyung_rad @DrRichardDo @MishalLala @HardingJJMD bit.ly/45YVCcB
James J. Harding, MD retweeted
NRG1 fusion-positive solid tumors: clinical detection, genomic landscape, and real-world data in #PDAC
@JNCI_Now
doi.org/10.1093/jnci/djaf361
🔎NRG1+ pts at Memorial Sloan Kettering
👉76,531 pts > 48 NRG1+ cases
👉Young pts, enriched in RAS WT PDAC
👉RNA testing is key
@myESMO




































