Taner retweeted
Programming biological behavior with AI-guided de novo protein design. www.cell.com/molecular-cell/fulltext/S1097-2765(26)00615-5
Taner retweeted
GABA regulates neuronal, immune & gut-brain signaling in preclinical models
LAB synthesize GABA via GAD; strain-specific GABA-T route needs validation
GABA-enriched foods may improve flavor and offer health benefits
Genetic editing, co-culture & stimulation may boost GABA yield
Taner retweeted
Could gut bacteria from long-lived people be used to treat Alzheimer's (AD) & aging? NMN-producing bacteria from healthy older adults were tested in a worm model of AD. Lifespan was extended & behavioral deficits were less 🪱💪😋 What if we ate them?
mdpi.com/2304-8158/15/20/365…
Taner retweeted
Akkermansia protects against endometritis
A.muciniphila protects against endometritis by driving tyrosol production, which reaches uterus & suppresses inflammation. Work reveals metabolite-mediated gut-uterus axis linking microbiota to reproductive health
cell.com/cell-host-microbe/f…
Taner retweeted
FOXO protein regulates genes & extends lifespan in simple organisms. New review discusses how it organizes the epigenome in response to adversity signals: lower ATP, NAD+ & S-adenosyl-methionine (SAM) ⚡️
sciencedirect.com/science/ar…
Taner retweeted
We are all mosaics with our cells accumulating somatic mutations as we age. Now that is getting fully comprehensively quantified @CellCellPress
cell.com/cell/fulltext/S0092…
Taner retweeted
Spotlighting the macrophage cells in our blood and tissue, their role in diseases, and targeted interventions
cell.com/immunity/fulltext/S… @ImmunityCP
Taner retweeted
This is a beautiful way to visualize the pathophysiology.
B cells at different stages of differentiation occupy different compartments, express different surface markers, and drive different pathologies.
Based on this biology, it'd make sense that (for example) lupus would respond best to anti-CD19 therapies, while Sjögren’s would respond best to anti-BCMA -- though how that shakes out in trials isn't fully known.
Next-generation immune cell engagers for B cell depletion in autoimmune diseases
nature.com/articles/s41573-0…
rdcu.be/NecnUNkptUFa
This Review discusses the principles guiding the design of immune cell engagers and emerging stratgeies to improve safety and durability of response
Taner retweeted
Who needs #ozempic when you have #anktiva ??
Peer reviewed paper showing IL-15 promotes weight loss independent of lymphocytes....
pmc.ncbi.nlm.nih.gov/article…
Taner retweeted
Utilizing longitudinal data from 52,236 patients with cancer, this study created a multimodal atlas of cancer cachexia, demonstrating that weight-loss episodes are linked to systemic serologic signatures and specific tumor genotypes. dlvr.it/TVxNP3
Taner retweeted
Bacteria promote kidney stones
C. glucuronolyticum-like bacteria enriched in urine of calcium oxalate stone patients & promote CaOx crystallization via hippuric acid degradation & biofilm formation. Hippuric acid prevents bacteria-driven crystallization
cell.com/cell-host-microbe/a…
Taner retweeted
I want to learn more about baking soda and cancer....
pubmed.ncbi.nlm.nih.gov/1927…
Taner retweeted
Clogged arteries are not just a cholesterol problem.
Inflammation, insulin resistance, and damage to the arterial lining can all drive plaque buildup.
Check the daily food and lab markers that matter most for prevention.
drbrg.co/4q5CzWR
Dr. Eric Berg, DC, not MD; information only
ALT A person holds a garlic bulb. Text reads, "EAT THIS DAILY FOR CLEAN ARTERIES." Two circular images show arteries, labeled "BEFORE" and "AFTER.
Taner retweeted
In 100% agreement
Exercise should be a prescribed
New @JACCJournals @ACCinTouch scientific statement
jacc.org/doi/10.1016/j.jacc.…
Taner retweeted
Age-associated Autoimmunity Driven by T cell Immunosenescence biorxiv.org/content/10.64898…
Taner retweeted
Potential heart problems and top natural heart remedies:
1. A clot
Top remedies:
• Nattokinase
• Garlic
2. Plaque
Top remedies:
• Tocotrienols
• Vitamin K2
• Vitamin C
3. Cholesterol
Top remedies:
• Niacin
• TUDCA
4. Angina
Top remedies:
• Tocotrienols
• CoQ10
5. High blood pressure
Top remedies:
• Potassium
• Vitamin D
6. Homocysteine
Top remedy:
• B vitamins (nutritional yeast)
7. Enlarged heart
Top remedies:
• Vitamin B12
• TUDCA
*Make sure your iron isn’t too high
8. Murmur
Top remedy:
• B vitamins (nutritional yeast)
9. High pulse rate
Top remedy:
• Potassium
10. Arrhythmias
Top remedies:
• Potassium
• Magnesium
• TUDCA
Dr. Eric Berg, DC, not MD; information only
Taner retweeted
"Early-life high-fat diet accelerates the developmental trajectory of vagal satiation signaling and predisposes females to overconsumption."
Learn more in Cell Reports: cell.com/cell-reports/fullte…
Anna Kamitakahara & colleagues
@CellReports
ALT first page of paper : \"Early-life high-fat diet accelerates the developmental trajectory of vagal satiation signaling and predisposes females to overconsumption\"
Taner retweeted
Memory stays strong in old age when this brain enzyme is active nature.com/articles/d41586-0…
Taner retweeted
Cellular senescence: six decades of discovery and reinvention
link.springer.com/article/10…
