
Emmy Noether Research Group at the interface of pediatrics and reproductive potential | @dralexbusch
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ALT Figure Family pedigree, and longitudinal evolution of hormone concentrations and testicular volumes. (A) Pedigree of the proband (arrow) and his family. Solid symbols indicate individuals affected by the c.87del mutation, open symbols indicate unaffected family members. The KISS1 genotype is shown under each symbol. (B) Evolution of testicular volume, and LH, FSH, and total testosterone concentrations in patient II-1. (C) Evolution of inhibin B and AMH concentrations during follow-up in patient II-1. (D) Evolution of testicular volume, and of LH, FSH, and total testosterone concentrations in patient II-2. Periods of treatment are shown as green areas in charts B–D. AMH=anti-Müllerian hormone. FSH=follicle-stimulating hormone. LH=luteinising hormone. WT=wild type.























