The seed fund designed for founders in AI.

San Francisco
Joined May 2019
Back-to-back robot shipments to New Zealand and India this week — have fun in your new homes, Feather!
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Fragment is automating commerce. We think there are millions of businesses that haven't been invented yet. Not because folks lack imagination, but because it's too hard to build the financial systems that run them. Fragment removes that constraint. Today, people run companies. With Fragment, they'll run on their own. fragment.dev/v2
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Nice coverage of @GamowLabs from the @GradientVC portfolio in the Gemini 4 launch! "Researchers at Gamow Labs used Argon to analyze de-identified genomes from newborns with rare developmental lung disorders. In one case, Argon pinpointed a chromosomal rearrangement that routine software missed for years, and explained why it went undetected. On private Gamow Labs evals derived from real clinical and lab data, Argon topped on RareBench (57% on assistance with rare-disease diagnosis) and LabBench (52.2% on wet-lab reasoning). These advances point to faster diagnosis for families facing rare conditions." blog.google/innovation-and-a… @GoogleDeepMind
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Big G is back! 🙇 @GoogleDeepMind Gemini 4 takes the 👑 on @GamowLabs RareBench and LabBench by a healthy margin over previous champ Opus 5.5. A tip of the hat to @melvinjohnsonp, @taotu831, @divy93t, and the rest of the science team for this very strong release. We've moved essentially all of our biology and genomics research work to Gemini 4 in agy with science skills since joining the EAP program and look forward to seeing if this model can help diagnose some new kids!
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In rare disease research, scientists at @GamowLabs used Argon to analyse de-identified genomic data samples from newborns with rare developmental lung disorders. It successfully pinpointed a chromosomal rearrangement that routine software missed for years, and explained why it went undetected. Read more here: gamowlabs.com/bringing-exper…
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“If you overbuy, you could bankrupt the company by having too many lease commitments, and if you underbuy, you could knock down your growth trajectory and have a bunch of unhappy users,” said @thezbg, a general partner at @GradientVC wsj.com/tech/ai/ai-computing…
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Gradient retweeted
Very difficult problem to solve b/c every layer of the internet (not just captchas) are built for humans, not agents. We'll need to re-work a lot of the web infra to support agents, and even then, many vendors like Amazon may choose to block them regardless gradient.com/blog/posts/why-…
So in the last two days about half of my Muse use cases have vanished because the browser won’t do it any more. Are websites changing their policies? Bot detection???
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Gradient retweeted
Today, we’re announcing Zeroset’s $5.2M pre-seed round to deploy world models into enterprises, co-led by @GradientVC and @2048vc, with participation from Leblon Capital and others. Frontier intelligence is capable of enormously complex tasks. And yet with an abundance of general capability and mandate, automation still requires enormous handwork. The models and systems that exist today lack an understanding of the world they act in. Robotics faced a similar problem. Building capable robots required more than compute-scaling on policies; they needed representations of their environments, encoding state and how it changed under actions. Over time, those representations shifted from hand-specified states toward learned models of the world. What is missing in the enterprise is a general system that represents work and learns from it. At Zeroset, we believe the same paradigm that enabled progress in robotics can be applied to represent enterprise “worlds.” We open with Nebula, a system that captures the state and traces created as people and agents work across systems, using them to model how an enterprise works and changes over time. These models contain the decisions, dependencies, and unwritten processes bespoke to a company. They are derived from the enterprise, and they should belong to the enterprise. Companies should be able to use the best models for their work and train them on their own operating knowledge freely. The underlying system does not need to change. Nebula is currently in closed research preview. If your team is automating complex work or exploring how to learn from the work your organization already does, please contact us. We are building the system through which that intelligence becomes increasingly specialized to the enterprise, allowing agents to act through it, and models to learn from it. If you’d like to join us in building this future, we’re hiring researchers and systems engineers. Read more here: businessinsider.com/zeroset-…
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"Models off the shelf have no understanding of the dynamics of how an enterprise actually works," Akshat Kannan told Business Insider. "They have no understanding on how the work gets done." bit.ly/4dT905K
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Agents are only as good as their ability to remember the right things at the right time. Proud to back the @zerosetinc team building temporal memory for agents!! 🚀@akshatkannan @wzhang @GradientVC
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yeah @PhotonHQ powers all of them.
We created a list of the most notable AI agents that can live in your text messages, from general assistants to agents designed for families, travel, and work. spr.ly/6016BGaI8I
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Gradient retweeted
Photon is on today's news on X right now. 1.5K posts and counting 🚀 Thank you @sarahpereztc @TechCrunch for covering the story, @JoshConstine @gradientvc @vigsachi @Darian314 @rauchg @cory for believing in it before anyone else did. And to EVERY partner and developer who's built with us: we couldn't have gotten this far without you. RIP Apps, Long Live agents.
We raised a $4.5M seed to let agents text people. Since April: 50K+ developers, 450K monthly npm downloads and 10x revenue. Bring your agent to iMessage, WhatsApp and more → tryphoton.ai
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@PhotonHQ ($4.5M seed, co-led by @GradientVC and A, with @vercel, HongShan, @zfellows, Llama Ventures and Karman): New apps struggle to get downloaded, so Photon puts agents where people already are: iMessage and WhatsApp. Its open-source Spectrum SDK has 40,000+ developer sign-ups, revenue grew 10x in four months, and it's the default iMessage layer for Nous Research's Hermes agent. Co-founders @danieltian (CEO) and @ryanzhuuuu (CTO).
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Looking forward to chatting AI and genomic medicine at @GamowLabs with @labenz and @8teAPi on @AI_in_the_AM at 10:15. If we are lucky, our new robot will make a guest appearance.
AI Utopia, Rare-Disease Diagnosis & the Cost of Control | Joel Borgen and Daniel McKinnon Join us this morning, Wednesday, 30th September: • 9:30 AM PT — Joel Borgen, Author, Minnesota (@JoelBorgen) • 10:15 AM PT — Daniel McKinnon, CEO, Gamow Labs (@danielmckinn0n) 𝕏 Chat is Live on Screen, Come Join Us: xitter.cf/i/broadcasts/1AJEmvzvj…
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Gradient retweeted
AI is rapidly expanding the supply of therapeutic ideas, but turning them into effective medicines is still hard. In our new essay, our co-founder Melissa J. Moore explores how better mRNAs can unlock novel medicines, and why mRNA’s most important chapter is still ahead. kernalabs.substack.com/p/mrn…
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