building things
Estonia
Joined July 2008
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We are going to put it into a simulator, aren't we?
Scientists have finally mapped the full nerve network of the human clitoris for the first time, three decades after mapping male anatomy.
For nearly thirty years, detailed anatomical maps of male reproductive nerves have guided surgical practice, while the nerve pathways of the clitoris remained largely unmapped. Utilizing advanced high-resolution X-ray imaging and 3D modeling on post-mortem human tissue, researchers successfully delineated the entire trajectory of the main sensory nerves and their branching sub-networks. The study revealed that these dorsal nerves branch out in a complex, tree-like pattern extending into surrounding tissues, overturning decades of incomplete anatomical textbook assumptions.
This discovery carries clinical implications for pelvic, reconstructive, and gender-affirming surgeries. Prior to this research, surgeons lacked precise anatomical guides to reliably avoid nerve damage during complex procedures near the vulva, which frequently put patients at risk for loss of sensation or function. By establishing an accurate, high-definition roadmap of clitoral innervation, medical professionals can now adopt nerve-sparing surgical techniques, improving post-operative outcomes, patient quality of life, and equitable healthcare standards.
[Lee, J. Y. (2026). Neuroanatomy of the clitoris. bioRxiv. DOI: 10.64898/2026.03.18.712572]
I wonder when we'll have wet labs with AI's that can reverse engineer any chemical.
Any drink or food or a drug - just reverse engineer and synthesize your own.
We can call it wet vibe coding.
German Bidzilja retweeted
make it really good. make it beautiful and amazing. use lots of tokens and iterate until it's really great.
-- the buddha
I am surprised that people are surprised this is how I prompt Claude.
Talk to Claude the way you would a coworker. There's no secret to prompting. There's no need to be overly scaffolded or prescriptive for most tasks -- give Claude a goal, and it will figure it out.
Back in the Sonnet 3.5 days, your prompt mattered a lot. Nowadays, it's much more important to communicate to the model:
1. What you want it to do
2. How much effort you want it to spend
3. How it should verify that it did the right thing
If a Twitter profile would show how many followers your followers have then I'd had 118M proxy followers.
German Bidzilja retweeted
If you had enough resources, you could run an LLM on a wooden system of gears and diesel power. It would be massive, but watching the gears and levers move, it would be evident that the outputs are not the result of a mind. Part of the illusion of LLMs is the tiny scale of GPUs.
Platform risk is real even for nieche cases.
Hello
Unfortunately, @GitHub has banned us. They have orbital nuked the entire malware source code collection.
I tend to think about a great product as delightful - it puts a happy smile on my face when I use it.
Stumbled upon a delight on the IKEA's webshop -
The highlighted text on the webshop is is in IKEA's colors.
What a delightful nuance.
Hardly anybody notices such a detail, but somebody decided to do it. Thanks for putting a smile on my face today, somebody!
Amazing piece! If indeed such words were used then Eric might have confirmed the theories instead of refuting them.
This is exactly how an evil actor would recruit a wishful good actor do evil acts.
If they would say: "We aim to do good >even though< others might perceive it as evil," then that could genuinely be a typical contrarian way of doing good and important things (not caring what others think/say).
But if they say: Do work that is "always confused as evil" - then it is at least a weird way to put it out. And at worst it's a justification of doing evil acts while thinking that you are doing a deeply good work.
Okay. I’ll take the bait.
I went to work for Peter in 2013 with opposite politics.
He sat me down right at the beginning.
PETER: “I don’t want the (Thiel) Foundation to do good that the market can do. That is the job of the market. Likewise, I don’t want to do the good work that is seen as good. That work can be done by people richer, weaker and more needy of approval than we are. I want us to do only the work that is *deeply* good but somehow confused for being evil, because that is the work of the courageous and the strong. We strive to be both and that is where a small foundation can make the greatest positive difference. Go look for such good and let’s do that. But remember. Good has TWO different antonyms. What is “bad work”? It could be seen as shoddy work. Or it could be seen as evil work. And we can’t do shoddy work. Why? Because evil that isn’t competent never gets to be evil. It’s just pathetic. So we have to be exceptionally competent at the good work which we do to make sure it is always confused for evil.”
I thought it totally logical. So that’s the argument. And that’s classic Peter.
This is an old idea of his. And now you know.
Looking at the comments of this post then my take might be the most contrarian of all.
One phrase that we repeat with kids: Rushing is bad. Doing things fast is good.
It's a simple framework.
The hard part is to know where is the line between rushing and going fast.
Calling works where it's not a regular way to reach out.
Jason pushed to accelerate the deal by calling and asking to get it done in 1 day - and it worked, for him, because it wasn't a typical request.
It works as long as it's an exception and not a typical way.
Been working on a real estate deal for a while.
Yesterday I was told something was going to take 3-5 days to turn around.
I asked why? Answer: Because that's how long it usually takes.
Then I asked: What would happen if you called them and told them you need it tomorrow?
My attorney said she'd try. So she did. And what do you know? They said they could turn it around in a day.
Yet another reminder that the first answer is just a placeholder for "usually". If you settle for that, that's what you'll get. But there's another option on offer: The option you want. And if you don't ask, you don't get. And if you don't do, it won't be done.
Everything can be compressed.