Faculty at Dana Farber / Boston Children’s @DFBC_PedCare. Advanced genetic engineering of hematopoiesis Lab.
Boston, MA
Joined April 2019
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- Following273
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Pietro Genovese retweeted
Epitope Editing Strategy Could Enable Less Toxic Stem Cell Transplants
Ability to avoid pretransplant chemotherapy could open up #stemcelltransplants for patients who might otherwise be too sick or too high risk
@Genovese_Lab @DanaFarber
#epitopeediting
hubs.li/Q04p1s5p0
Pietro Genovese retweeted
🌟 #ICLE2026: Program Highlights
Session 07: HSC Genetic Engineering and Epitope Editing
🎤 Chairs: Mario L. Squadrito (Italy) & Dirk Busch (Germany)
@NaldiniLab @Genovese_Lab @CasiratiG
Find out more: lnkd.in/dX7aRAAK
#HSCEngineering #EpitopeEditing #GeneTherapy
Thrilled to see the great work from @danielevanbauer lab featured in @NatureBiotech! The discovery that a limited nucleotide pool in HSPCs constrains prime editing is a leap forward in gene editing technology. A huge shoutout to @SbastienLevesq4 and the entire team!
My postdoc work in the @danielevanbauer lab is out @NatureBiotech! We found that the limited nucleotide pool in hematopoietic stem and progenitor cells (HSPCs) constrains reverse transcription and thus prime editing (PE). nature.com/articles/s41587-0…
Pietro Genovese retweeted
My postdoc work in the @danielevanbauer lab is out @NatureBiotech! We found that the limited nucleotide pool in hematopoietic stem and progenitor cells (HSPCs) constrains reverse transcription and thus prime editing (PE). nature.com/articles/s41587-0…
Very proud of your achievements @ferrari_sam93 !! It has been a privilege contributing in mentoring such amazing young scientist!
I am deeply honored to receive the 2023 Early Career Investigator Award by @ESGCT at the Annual Congress in Brussels together with @alessionahmad. This prestigious recognition would not have been possible without my SR-Tiget colleagues and mentors @NaldiniLab and @Genovese_Lab.
Excited to share our latest publication about epitope editing in hematopoietic stem cells to enable targeted immunotherapy for acute myeloid leukemia. Congrats to @CasiratiG and all collaborators for this amazing work.
nature.com/articles/s41586-0…
I'm thrilled to announce that our work, 'Epitope Editing Enables Targeted Immunotherapy of Acute Myeloid Leukemia,' is out today in Nature journal!
Link: nature.com/articles/s41586-0…
doi: doi.org/10.1038/s41586-023-0…
Pietro Genovese retweeted
Congrats to Zeng @Genovese_Lab @danielevanbauer et al. on their paper "Base Editing of Human Hematopoietic Stem Cells."
Thanks for using #crispresso2! doi.org/10.1007/978-1-0716-2…
Pietro Genovese retweeted
Gene editing stem cell transplants makes myeloid and T cell therapies safer, according to data at #ASH22 buff.ly/3hCEDqz
Pietro Genovese retweeted
With #geneediting, researchers restored levels of CTLA-4 in T cells from patients with CTLA-4 insufficiency. In mice, they improved symptoms.
ASGCT members involved: @RealDrfox, MbChB, PhD; Claire Booth, MBBS, PhD; Pietro Genovese @Genovese_Lab, PhD: ucl.ac.uk/news/2022/oct/new-….
Pietro Genovese retweeted
"Unless things change dramatically, the millions of people #CRISPR could save will never benefit from it. We must, and we can, build a world with #CRISPR for all."
#healthjustice @igisci @nytimes
nytimes.com/2022/12/09/opini…
eppro02.ativ.me/appinfo.php?… ready to share our exciting data tomorrow morning!🩸#ASH22
Pietro Genovese retweeted
Researchers at @SanRaffaeleMI, led by Dr. Maria Ester Bernardo, developed an MSC-based co-culture system to optimize the transplantation outcome of #CRISPR-Cas9 gene-edited human #hematopoietic stem and progenitor cells. 🧬
#OpenAccess | 🔗 bit.ly/3Cjn8mR
Pietro Genovese retweeted
Finally out in @MolTherapy our new work showing that #mesenchymal stromal cells help "hand-in-hand" #CRISPR/Cas9 edited human #hematopoietic #stem cells to engraft. By Bernardo's lab in coll with @DiMiccoLab and @NaldiniLab. bit.ly/3A5LY71. Pic created with DALL·E 2.
Pietro Genovese retweeted
These are exciting but hard times for #genetherapy . It’s heartbreaking to witness withdrawal of effective gene therapies from the market. They are often the only cure for many rare conditions, saving lives of other human beings.
Don’t miss this!
Ensuring a future for gene therapy for rare diseases.
Comment from Alessandro Aiuti @francescapasi and @NaldiniLab San Raffaele Telethon Institute of Gene Therapy, Italy
nature.com/articles/s41591-0…
Pietro Genovese retweeted
If the food will not go to Italians, Italians will go to the food (and wine).
Typical (and nice) Portuguese Dinner with the lab and collegues 🤤
@NaldiniLab
@Genovese_Lab
@KajasteLab
@ferrari_sam93
@FASEBorg
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Pietro Genovese retweeted
Gene editing of Hematopoietic Stem Cells with @Genovese_Lab
Dana-Farber/Boston Children’s Cancer and Blood Disorder Center, Boston, USA
jobrxiv.org/job/genovese-lab…
#ScienceJobs #geneediting #genetherapy #immunotherapy
Pietro Genovese retweeted
Do you want to describe a particular technique aimed to enhance #CRISPR #editing for #nextgeneration #therapies?
@JoVEJournal is the leading video journal aimed at increasing the visibility and reproducibility of research.
Submit your abstract here!
jove.com/methods-collections…
Pietro Genovese retweeted
New post-doctoral position open @ SR-Tiget (Milan, Italy) on #CRISPR #editing of human #hematopoieticstemcells in Dr. Anna Villa’s lab. Great opportunity to contribute to advance this amazing tool toward clinics! linkedin.com/posts/samuele-f…
Pietro Genovese retweeted
Very interesting technique developed by SR-TIGET for retrieval of viral integrations from liquid biopsies just published @NatureMedicine !
Kudos to #Montini's team!
#genetherapy #bigdata #lentivirus #viralvectors #invivodelivery #liver #clonaltracking
nature.com/articles/s41591-0…
