@GenSCAPE_Lab

Genomic Studies of Contemporary & Ancient Populations and their Evolution Lab @ University of Chicago 🌎🌍🌏 (Tweets by @MaanasaRaghavan + Raghavan Lab members)

 Chicago, IL
genscape-lab.com/
Joined January 2019
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28Media
Thrilled to share our lab's newest paper! A collaboration with @NirajRai3 and team, led by GenSCAPE postdoc Shreya Ramachandran and @NagarjunaPasup5, with our incredible team across India and Sri Lanka! 🧵below on what we found studying South Asian gut microbiomes:
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🥛Some communities like the Spitians have eaten wheat & dairy for generations, but others only recently added them after urbanizing; we see this in their Bifidobacterium 🩺 Controlling for community, urban folks show lower diversity & more Megamonas, linked to obesity risk.
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🤝🏽 We are so grateful to every community member who partnered with us. We returned to all participant communities to thank donors in person & share results! Paper: tandfonline.com/doi/full/10.... Press release: biologicalsciences.uchicago.…... Happy to answer questions!
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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
SPAAM-community@spaam_communityApr 6
What did #ancient #viral #ecosystems look like? 🦠🧬 Sedimentary #aDNA from lakes and oceans reveals 2,000+ viral taxa and shows how #virus–host interactions changed from the #Pleistocene to today. doi.org/10.1093/ismejo/wrag0… #MetagenomicsMonday #SPAAM #aDNA #sedaDNA

DNA virus–host patterns in lake and marine environments over the last glacial cycle

Abstract. Viruses are integral to population dynamics, biogeochemical cycling, and host evolution, making them essential for ecosystem function. We explore

academic.oup.com
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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
GuangLin He@GuanglinHApr 4
Complex peopling history and expansion events inferred from large-scale modern and ancient Y chromosome sequences | Science Advances science.org/doi/10.1126/scia…

Complex peopling history and expansion events inferred from large-scale modern and ancient Y...

Ancient Y chromosome lineages trace Paleolithic migrations and Neolithic expansions that shaped East Asia’s paternal history

science.org
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Cesar Fortes-Lima@CesarFortesLimaMar 26
📢Our aDNA study has been published today in @NatureComms! A great collaboration with Ricardo RodríguezVarela, Anders Götherström, @cschlebu & team. Analysis of medieval burials from Ibiza reveals genetic and pathogenic diversity during the Islamic period. nature.com/articles/s41467-0…

Analysis of medieval burials from Ibiza reveals genetic and pathogenic diversity during the Islamic...

Nature Communications - Ibiza, an island in present-day Spain, was under Islamic rule between the 10th and 13th centuries CE. Here, the authors analyse the remains of thirteen individuals from...

nature.com
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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
Carmina Barberena-Jonas 💛🍋🌻🌕✨@BarjonCarFeb 25
Last month, I published part of my PhD thesis in @NatureMedicine : Clinical genetic variation across Hispanic populations in the Mexican Biobank. 🔗 nature.com/articles/s41591-0… ... and we got the cover of the February issue!
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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
Andres Moreno-Estrada@morestradaFeb 19
Second time the MX biobank project (mxbiobank.org) gets the cover in a @Nature journal! This time in @NatureMedicine highlighting the work by @BarjonCar on Clinical genetic variation in Mexico. Another amazing cover by @mauguz33! nature.com/nm/volumes/32/iss…
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Andres Moreno-Estrada@morestradaJan 21
Our paper on clinically relevant genetic variation in the MX Biobank is out today in @NatureMedicine! Big congrats to @BarjonCar, who led the development of the MexVar platform. A joint effort by @cinvestav @inspmx @incmnszmx @LIIGH_UNAM and @ucsc nature.com/articles/s41591-0…

Clinical genetic variation across Hispanic populations in the Mexican Biobank

Nature Medicine - Analyzing data of the Mexican Biobank project, a new study finds regional differences in clinically relevant genetic frequencies and presents MexVar, a publicly accessible...

nature.com
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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
Genetics Society of America@GeneticsGSA30 Dec 2025
In #GENETICS, @JeremyJBerg et al. introduce an evolutionary model of complex disease susceptibility, where a variant's effect on disease risk follows from liability threshold model and a variant's effect on fitness follows from its effect on disease risk. buff.ly/XkB8hPb
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ERC Felix@felix_erc28 Nov 2025
🚨 NEW pub in @ScienceMagazine !!! 🚨 🐈‍⬛🐈 The dispersal of domestic cats from North Africa to Europe around 2,000 years ago 🐈‍⬛🐈 Our article provides novel evidence suggesting new hypotheses about the history of domestic cats! 🧬
Cover of the vol. 390, issue n°6776 of Science (AAAS) featuring a shorthair domestic cat.

ALT Cover of the vol. 390, issue n°6776 of Science (AAAS) featuring a shorthair domestic cat.

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GenSCAPE (aka Raghavan) Lab 🧬 retweeted
Marco De Martino@_MarcoDeMartino28 Nov 2025
After a four-year journey, my PhD work is out in @ScienceMagazine! Endless gratitude to the amazing @felix_erc team, all coauthors and collaborators, and my loved ones. Without you all this could not be real! 💛🐱✨ @ERC_Research @NatGeo @unitorvergata2 #aDNA
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Gaceta UNAM
@Gaceta_UNAM10 Nov 2025
Carla Daniela Robles Espinoza, coordinadora del @LIIGH_UNAM, nos comparte su experiencia de hacer el doctorado en el Reino Unido… #AlumniUK ➡️ t.ly/wBxIO

Inspiración para la siguiente generación de estudiantes - Gaceta UNAM

Para el British Council es un orgullo ser un puente entre México y el Reino Unido, donde el trabajo conjunto de los jóvenes siempre es más fuerte gracias a la constante cooperación de todos, expresó...

gaceta.unam.mx
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Esha Bandyopadhyay, Ph.D.@eshab0530 Oct 2025
✨Thrilled to share that the first chapter of my Ph.D. thesis is NOW OUT in Science Advances (science.org/doi/10.1126/scia…)! ✨🥳🎉 🧬. This couldn't have been possible without the support of everyone involved @MaanasaRaghavan @NirajRai3 @Conydelafc @mootspoints and others.

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Ancient and present-day human genomes shed light on ~1300 years of genetic admixture and continuity in the northern Himalayas.

science.org
GenSCAPE (aka Raghavan) Lab 🧬@GenSCAPE_Lab30 Oct 2025
1/n Delighted to share our newly published work in Science Advances, investigating human genetic histories at the northern frontier of the Himalayas 🧬🏔️: science.org/doi/10.1126/scia…

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Ancient and present-day human genomes shed light on ~1300 years of genetic admixture and continuity in the northern Himalayas.

science.org
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1/n Delighted to share our newly published work in Science Advances, investigating human genetic histories at the northern frontier of the Himalayas 🧬🏔️: science.org/doi/10.1126/scia…

Dynamic human admixture histories over the past ~1300 years at the northern Himalayan frontier

Ancient and present-day human genomes shed light on ~1300 years of genetic admixture and continuity in the northern Himalayas.

science.org
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5/n This study provides first insights into the admixture dynamics and adaptive histories at the northern frontier of the Himalayas.
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6/n This study could not have been possible without the incredible support of the local communities in Himachal Pradesh, our archaeological collaborators, and every co-author who made this work possible - Thank you all! 🥳
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