We use genetics and genomics to understand neurodegenerative diseases. We also use modern approaches to develop more predictive models for Alzheimer's disease.

The Jackson Lab, Bar Harbor ME
Joined March 2016
Three is the magic number (for posters at #AAIC23)! Visit Stacey Rizzo from the @RizzoLab to learn more about animal models for late onset #Alzheimers disease being developed by the @IndianaUniv @jacksonlab @PittTweet @Model_ad_alz Consortium #EndAlz
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Phenomenal talk by @kateeeemily today at #AAIC23 exploring the glial influence on exacerbating ARIA in AD mouse models. Exciting findings and looking forward to seeing where this work goes!
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Stop by Posters 43 & 44 to chat with @MayoClinicNeuro’s Joseph Reddy and @jacksonlab’s Asli Uyar about their work using resources from the #Alzheimers Disease Knowledge Portal and @Model_ad_alz to help #EndAlz #AAIC23 @NIHAging
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Headed off for a long travel day to Amsterdam for #AAIC23! Excited to be presenting so very cool work (with new data 🥳) that I’ve been working on with @ErikBloss and @garethhowell10! Make sure to come by my poster on Tuesday P3-012 to learn more!
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It will be drop the mike time for @cowabunga314 and I!
To close out the #AAIC23 make sure to check out the Thursday Genetics, Biomarkers and Endophenotypes in AD mouse models session, co-chaired by the amazing @cowabunga314! Featuring talks by my mentor @garethhowell10 and @cowabunga314!
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Biggest contingent of @GHowell_Lab @jacksonlab at #AAIC23 ever! See presentations from @cowabunga314, @Heuerwego, Alaina Reagan, Olivia Marola and I. APOE, microglia and synapses, vascular health, toxic metals, the eye as a biomarker, and genetic diversity - something for all!
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Check out presentations by former @GHowell_Lab @jacksonlab members @kateeeemily and @Becca__Buchanan at #AAIC23. The Howell lab network spreads.
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Replying to @CarterLabJax
@CarterLabJax’s Catrina Spruce, @GMilinkeviciute, and @garethhowell10 of @Model_ad_alz fame with the biodomains board at the @NIH Pavilion. Check it out and learn more about the #FreeData, animal models, and experimental tools available at booth 212! #EndAlz #AAIC23
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Stop by Asli’s from ⁦@gwcarter⁩ lab and ⁦@cowabunga314⁩ ⁦@GHowell_Lab⁩ poster at P2-043 showing how mouse genetic diversity differentially regulates brain aging and response to amyloid.
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Check out AARF grant awardee Olivia Marola @GHowell_Lab @GHowell_Lab @jacksonlab poster (P2-029) on studying the role of the ANG/TIE2 in vascular health and ADRD using novel mouse models. #AAIC2023 #AAIC23 #EndAlz
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Introducing MODEL-EyeD at #AAIC2023 leveraging novel @Model_ad_alz and @GHowell_Lab mouse strains to evaluate the potential of the eye as and additional biomarker for AD. Poster P2-245.
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Are you looking for some research experience before deciding where to take your science career? Come join us @jacksonlab! @alzassociation #ENDALZ
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Want to understand how @Model_ad_alz ranks drug candidate submissions on the STOP-AD portal? Check out the latest publication! #ENDALZ #Ittakesavillage
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Exciting to see the first fruit of a collaboration between the Howell lab and @ErikBloss! The interaction between microglia and synapses is thought to be important across the board, however, perhaps this is just the case for certain genetic contexts? Check it out!
SUPER excited to share a preprint reporting some cool work I've been doing with @ErikBloss and @garethhowell10 at @jacksonlab! A 🧵...
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SUPER excited to share a preprint reporting some cool work I've been doing with @ErikBloss and @garethhowell10 at @jacksonlab! A 🧵...
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Celebrating Howell lab 10 years this am! Big shout-out to lab members that helped contribute to our success @kateeeemily @IleSotoR @leahc_graham @Hatwilliams2014 @Becca__Buchanan @frosteeze! #ENDALZ #CureGlaucoma @jacksonlab @garethhowell10 @Heuerwego @StanleyHYang
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Proud to have our postdoc Olivia Marola and her family participate in the Bangor @alzassociation walk! #ENDALZ
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🎉 Celebrating #NPAW2022! Dr. Alaina Reagan is a postdoc in the @GHowell_Lab at @jacksonlab, researching how age and genomic factors influence cerebrovascular function in Alzheimer's Disease and dementia: jax.org/people/alaina-reagan #JAXTrainee
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Great spotlight of @cowabunga314 and the hard work of @Model_ad_alz! @jacksonlab @RaviSPandey15 @RizzoLab @adrianoblak @gwcarter @garethhowell10
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