Interventional imaging/Research Fellow @Cedars Sinai Medical Center, Clinical Lecturer @UCL, Chief Medical Officer @MycardiumAI Core Lab.
Joined March 2018
- Tweets52
- Following124
- Followers94
- Likes81
George Thornton retweeted
Heart function stayed stable at 1 year after carefully monitored withdrawal of heart failure therapy in breast cancer survivors with recovered anti-HER2 cardiotoxicity. Work from our group at @ucl, presented by @bmdwsg as a Late-Breaking Trial at #ESCCongress 2026 & published simultaneously in @ehj_ed: HER-SAFE. @TheBHF @escardio @MycardiumAI #CardioOnc
🔗 academic.oup.com/eurheartj/a…
Our study in @JAMACardio: 72 patients with severe AR, paired CMR, echo and CPET before and 7 months after AVR. LV volume fell 44% and mass 21%, but scar was associated with less remodelling and peak VO2 unchanged. @UCL_ICS @TheBHF @NHSBartsHealth
bit.ly/4zImhaG
George Thornton retweeted
Excited to see our work on myocardial fibrosis and reverse remodelling after AVR for chronic aortic regurgitation published in @JAMACardio! lnkd.in/eCcS-BjD
At 7 months post AVR:
🔹 LVEDV ↓44%
🔹 LV mass ↓21%
🔹 Matrix ↓15%
But focal scar did not regress #whyCMR @TheBHF
George Thornton retweeted
How do you handle persistently low dock position during #TMVR with the #M3 system?
If usual maneuvers fail, 2nd transseptal puncture can be considered for double guide sheath technique. Here's what we learned @CedarsCards @RajMakkarMD, out in @JACCJournals Interventions. 👇
George Thornton retweeted
🫀 First-in-human valve-in-valve TAVI in mechanical prostheses
Bench-to-bedside study: disc dislodgement & retrieval followed by successful TAVI.
Published in European Heart Journal.
👉 academic.oup.com/eurheartj/a…
@escardio @PCRonline @secardiologia @CNIC_CARDIO @sacyl @TCTMD
George Thornton retweeted
So proud of @ShubhaPawar for leading this cross-disciplinary collaboration that distills today’s best evidence in aortic regurgitation (diagnosis and treatment), now in @JACCJournals. IM residencies: @ShubhaPawar is applying this season - take note. @CedarsSinai @CedarsSinaiMed jacc.org/doi/10.1016/j.jacc.…
George Thornton retweeted
Ever wondered why some pts feel every balloon inflation, while others feel nothing? 💭
Or why severe ischemia can be asymptomatic?
Our placebo-controlled, n-of-1 study — simultaneous in #Circulation & #TCT2025 — shows collateralization may be key.
🔗 ahajournals.org/doi/10.1161/…
George Thornton retweeted
ahajournals.org/doi/10.1161/… Highest congratulations to the authors, Dr. Signe Glargaard et al
George Thornton retweeted
KOLs boost Early Aortic Valve Intervention in Patients with Asymptomatic AS--Despite Dubious Evidence:
@JAMACardiology featured a strong editorial urging cardiologists to intervene early in patients who have aortic valve stenosis and no symptoms. I do not agree via @drjohnm
sensible-med.com/p/kols-boos… @gbiondizoccai @Coronary4front @cpgale3
George Thornton retweeted
Should PCI be an option for first line management of stable angina symptoms?
Point and counterpoint in @CircOutcomes with final word from @bnallamo and @TCTMD
ahajournals.org/doi/full/10.…
@rallamee
George Thornton retweeted
The symptom stratified analysis of ORBITA2 and the ORBITA-STAR trial both presented at #EuroPCR2024 and simultaneously published in @JACCJournals by @FloSimader and @rajkumar_chris. PCI isn’t a therapy for all symptoms, it’s a therapy for angina @rallamee @mshunshin
George Thornton retweeted
.@FloSimader on #ORBITA-2 at #EuroPCR:
📌Poor correlation between symptoms & disease severity
📌Symptom nature is a powerful predictor of the placebo-controlled efficacy of #PCI
📌Rose angina & typical angina are excellent predictors of the placebo-controlled efficacy of PCI
📌Other symptoms such as SOB are poor predictors of the placebo-controlled efficacy of PCI
George Thornton retweeted
In contention for BEST study of the year thus far
N of 1 trial of patient-blinded occlusion of target vessel
The more angina was inducible, the more symptom relief after PCI
Best 2 figures
Now, how best to verify if symptoms truly are angina?
In ORBITA-STAR, angina verification with an ischaemic stimulus powerfully predicted response to PCI. #EuroPCR2024
Perhaps we have been too focused on treatment when the problem always lay in the diagnosis! Published today in #JACC jacc.org/doi/10.1016/j.jacc.… @rallamee
George Thornton retweeted
ICYMI: Watch this insightful video by Drs. @rallamee & @rajkumar_chris where they shed light on their #JACC paper discussing the N-of-1 trial of angina verification before #PCI.
Access the full 📄 here: bit.ly/4bfHcoJ
#EuroPCR #ORBITA @hmkyale
George Thornton retweeted
In ORBITA-STAR, angina verification with an ischaemic stimulus powerfully predicted response to PCI. #EuroPCR2024
Perhaps we have been too focused on treatment when the problem always lay in the diagnosis! Published today in #JACC jacc.org/doi/10.1016/j.jacc.… @rallamee
George Thornton retweeted
Amazing to see a brilliant friend and colleague @MikeFoley89 present the #ORBITA-COSMIC trial of the coronary sinus reducer with simultaneous publication in @TheLancet @rallamee @ImperialNHLI @ImperialNHS #ACC2024
thelancet.com/journals/lance…
George Thornton retweeted
Here we go again! Want to see if the coronary sinus reducer works in refractory angina? Watch @MikeFoley89 present the results of the ORBITA-COSMIC in the main arena at #ACC this Monday #ORBITA @fiyyazAJ @mshunshin @ShaynaChotai @rajkumar_chris @FloSimader
George Thornton retweeted
New Stress Perfusion CMR webinar ‼️with internationally renowned experts @chiarabd and @sven_plein 🧲
Follow the link to register 👇🏻
tinyurl.com/Bscmrwebinar
BSCMR comms team @T_Naneishvili @gabycaptur
BSCMR president @ColinBerryMD
@SaulMyerson
