Infectious Disease physician-scientist studying #microbiome in #HIV | @UCLA_ID | Mom of boys #twinmom | Sports enthusiast. Thoughts all mine.
Los Angeles, CA
Joined December 2013
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Jennifer Fulcher MD PhD retweeted
I know first-hand how important Infectious Disease (ID) physicians are in a public health crisis. Yet, 80% of U.S. counties do not have an ID physician. To protect our nation’s public health, we must break down the barriers that stop medical students from becoming ID physicians.
Jennifer Fulcher MD PhD retweeted
Our latest is out in @J_Immunol! This was a fun little project where we explored how dysfunctional monocytes contribute to NK cell activation in severe COVID-19. We used a combination of computational exploration and in vitro validation experiments!
journals.aai.org/jimmunol/ar…
Jennifer Fulcher MD PhD retweeted
The prayers for #DamarHamlin are beautiful, but @NFL, please also consider spending 2 minutes before tomorrow’s games showing a demo of hands-only #CPR & encouraging viewers to learn. With your audience, this could save lives ❤️🙏🏽
Read on to learn how to do hands-only CPR ⬇️
Jennifer Fulcher MD PhD retweeted
“We, [ID] doctors, are becoming a finite resource because people can’t financially make it work. They’re burnt out and their reward is, ‘Here, we’re going to pay you less,’ says IDSA Past President Daniel McQuillen, MD, FIDSA (@McQHoya81) about potential #Medicare payment cuts.
Jennifer Fulcher MD PhD retweeted
Which bacteria represent the most urgent threat to health? And how does this vary by region? Our estimates in @TheLancet try to address these questions @IHME_UW
NEW—Common #bacterial infections were the 2nd leading cause of death in 2019 and linked to 1 in 8 deaths globally, according to an analysis by @IHME_UW: hubs.li/Q01sTzjY0 #WAAW2022
ALT Figure 4: Global number of deaths (A) and YLLs (B), by pathogen and GBD super-region, 2019
Other support from @dgsomucla @UCLA_ID @DOM_UCLA @UCLAFSPH @PAC_UCLA UCLA-CDU CFAR @NorthwesternU @ISGMH @ChildrensLA 8/n
Collectively, our data showed that gut microbiome changes do not occur in early HIV but may suggest a role for the gut #microbiome and #inflammation in #HIV susceptibility – an exciting area for more research! 7/n
Important to note that due to sample availability our study included only men who have sex with men, had limited sample size, and only followed up to 1 year after #HIV acquisition. 6/n
Prior to HIV we also observed increased inflammatory cytokines and bioactive lipids in those who acquired HIV compared to those who did not. 5/n
Where we did see the greatest #microbiome difference was *before* HIV. Using a risk-matched control cohort we observed decreased Bacteroides spp and increased Megasphaera elsdenii in those who acquired HIV compared to those who did not. 4/n
Using plasma #metabolomics we did observe changes in #bile acids following acute HIV which may interact with gut bacteria in early HIV. 3/n
Chronic #HIV has been associated with dysbiosis leading to ongoing inflammation but it is not known when this begins. Using #longitudinal samples we followed the #microbiome before and after acute HIV. Early after HIV we found limited change in the #microbiome. 2/n
Thrilled our latest work on #HIV and the #microbiome now published in @eBioMedicine tinyurl.com/ymtr3xc6
Great team with @curehiv1 Steven Shoptaw Pamina Gorbach @Mustanski Richard D’Aquila Jesse Clark Michele Kipke and @NIDAnews cohorts @uclaMstudy @radar_nu @WeAreHYM 1/n
👉💊 Take note, HAART is an antiquated and redundant term, and no longer has clinical relevance. All antiretroviral therapy used nowadays is "highly active", so the term ART is preferred instead. #IDTwitter #MedTwitter #FOAMed