Immunology, monocyte signaling, immunosenescence, immunity of sepsis, immunotherapy, immunometabolism, innate immunity, NK cells

Joined May 2020
Vojtěch Graman, Adéla Jílková and colleagues @FricLab @IHBTcelltherapy @FNUSA_ICRC report that #TLR stimulation of #NKcells modulates cytosolic Ca2+ levels and influences NK cell #Degranulation and #Cytotoxicity 📖 buff.ly/kThKP4v
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Proud to be highlighted with our paper on NK cell immunometabolism ... collaboration of @FNUSA_ICRC @IHBTcelltherapy @frcbsresearch @Jahan_Farhana_1 @Veripalvelu @HortovaMarcela
Importance of glutaminase activity in supporting NK cell respiratory metabolism and cytotoxic function, and the need for caution when combining glutaminase inhibitors with NK cell-based therapies @HortovaMarcela @FricLab @FNUSA_ICRC 🇨🇿 journal-inflammation.biomedc…
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FricLab at @CSAC_CZ 2025 conference Jan @FricLab presented pre @BEATsepsis data @MichalSantocki BMniche remodelling in sepsis, @zuzanatomasik EoE project, @pap_joanna postCOV neutrophils 👏 @blzk_gabriela for winning the Travel🏆 @HortovaMarcela coorganised conf 👏Organisers!
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Moments from Friday’s Researchers’ Night: Scientists @FricLab revealed one of our body’s greatest riches – the immune system. The scientific show went on inside a Faraday cage – a lab for exploring the body’s most delicate signals. #nocvedcu
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13th @CSAC_CZ conference is coming! Looking forward to welcome you in Mikulov 4-7-10.! 🍂🍇 👩‍🔬Check program conference.csac.cz/scientifi…  🧪Register for lunch workshops conference.csac.cz/hands-on-… 🚴‍♀️ Join us for extraordinary bike&scientific discussion conference.csac.cz/accompani…
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Thanks @zuzanatomasik et al for leading the @FricLab efforts to present! #immunesystem #sepsis awareness @BEATsepsis @BendickovaKami @HortovaMarcela
🚀 Just 3 more sleeps until Festival of Science & Technology Brno 2025! 🧠 Learn life-saving first aid 🔬 Step into dust-free cleanrooms & drug production 🦠 Explore the immune system in action 📅 Sept 5–6 (9–18h) Can’t wait to see you there!
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Congrats @VeronikaBosak !!
👏 Huge congratulations to the scientists honored for the best PhD publications at #ICRCDAYS2025! 🥇 Veronika Bosáková: dx.doi.org/10.1038/s12276-02… 🥈 Natália Vadovičová: dx.doi.org/10.1073/pnas.2321… Both presented their work at the conference finale.
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👏 Huge congratulations to the scientists honored for the best PhD publications at #ICRCDAYS2025! 🥇 Veronika Bosáková: dx.doi.org/10.1038/s12276-02… 🥈 Natália Vadovičová: dx.doi.org/10.1073/pnas.2321… Both presented their work at the conference finale.
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The Friday Night reserved for the immune system in action - brought to you by @FricLab @zuzanatomasik @blzk_gabriela and team … #organoids #sepsis @BEATsepsis
🚀 Just 3 more sleeps until Festival of Science & Technology Brno 2025! 🧠 Learn life-saving first aid 🔬 Step into dust-free cleanrooms & drug production 🦠 Explore the immune system in action 📅 Sept 5–6 (9–18h) Can’t wait to see you there!
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🚨 We introduce you another keynote speaker at #ICRCDays2025 (Sept 9–10): Prof. Yoav Shaul - @HebrewU 🔬 He explores how cancer metabolism drives tumor spread — with a focus on breast cancer. Could oncometabolites be the key to treatment? 🧠 More info: bit.ly/4ltUnI0
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Fric_Immuno_Lab retweeted
With @katerinarohlena pleased to announce the 2026 Prague Metabolism and Signaling Meeting (June 24-27). Two Keynotes (Vousden & Hall) and 30+ speakers in metabolism, mitochondria, aging, mTOR, & more. Please RT. Info, registration, & student discounts at: praguemetabolismsymposium.co…
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Pleased to be invited to speak at the 18th Annual Conference of the Czech Society for Intensive Medicine (CSIM). @BEATsepsis was introduced and discussed with the medical and scientific community. @FricLab @FNUSA_ICRC @EU_HaDEA @Science_MEDMUNI
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Thanks for highlighting our work @friclab @FNUSA_ICRC @Science_MEDMUNI
TGF-β suppresses both NK cell cytotoxicity and migration, limiting their ability to eliminate leukemic cells and infiltrate the bone marrow niche dovepress.com/tgf--decreases…
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This is how we enjoyed the #openhouse2025! We were proud to be part of this year’s festival. Visitors joined us for tours of the Translational Medicine Center labs, where our researchers themselves guided you. @FricLab
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🌍@FricLab and @HortovaMarcela represented 🇨🇿 science at top global forums! At the European Parliament (ESA annual meeting) & WIRM in Davos, they shared cutting-edge sepsis research — mucosal organoids and long-term immune impacts in children. ➡️Read more bit.ly/4iM5PfN
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@FricLab we are comming with @BEATsepsis & FIBROsep and many other projects
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Countdown to the 5th #WorldSepsisCongress – Sessions 4–6. Meet the experts. S4: Novel Approaches to Pathogen Detection and #Sepsis Diagnostics S5: The Immunization Agenda for Sepsis S6: Pathways for Sepsis Care – Integrated Emergency, Critical, and Operative Care worldsepsiscongress.org
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Today! 5th WORLD SEPSIS CONGRESS-Satellite Session: Metabolism of Sepsis: Avenue for Improved Diagnosis and Therapy. Co-organised @HortovaMarcela @BEATsepsis 🗣️Sepsis-Associated Immunosuppression: Long-Term Immunometabolic Defects by @HortovaMarcela @FNUSA_ICRC @Science_MEDMUNI
#Metabolism lovers, mark your calendars. Before the 5th #WorldSepsisCongress, on February 25 we’re hosting the satellite session: “Metabolism of Sepsis: Avenue for Improved Diagnosis and Therapy” Via YouTube Livestream| 16:00 CET | 9:00 CST 🔗 For more info: worldsepsisday.org/news/2025…
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Save the date!
BEATsepsis is co-organizing a Satellite Symposium at the 5th #WorldSepsisCongress! Join us on Feb 25, 2025, 16:00 CET for “Metabolism of Sepsis: Avenue for Improved Diagnosis & Therapy”, including @FricLab 's @HortovaMarcela with insights on sepsis-associated immunosuppression!
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