Evolutionary systems cell biology (that just about covers everything). Exploring the biology of infectious disease, peroxisomes & nuclear pore complexes.
Seattle, WA
Joined September 2012
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This preprint, now finalized for @eLife, includes several new, stunning figures from Nat. They highlight epitopes on the spike protein that, despite extensive mutations, remain susceptible to our #nanobody repertoire's neutralizing effects.
elifesciences.org/articles/8…
@RoutLab_RU
Exciting news! Our latest research "Nanobody repertoire generated against the spike protein of ancestral SARS-CoV-2 remains efficacious against the rapidly evolving virus" is on @biorxivpreprint. @johndaitchison @RoutLab_RU @IntActOme biorxiv.org/content/10.1101/… 🧪🔬 #SARSCoV2
Fred D. Mast retweeted
Wonderful (and long overdue) news. Proud day for @UW @UWproteindesign
Fred D. Mast retweeted
A hearty congratulations to our colleague, David Baker, on receiving the @NobelPrize for his visionary work in protein design. @UWproteindesign
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Fred D. Mast retweeted
PHOTO: David Baker @UWBiochemistry @UWproteindesign @uwmedicine taking via computer at his Seattle home early this morning shortly after learning that he had received #NobelPrize2024 in chemistry for computational protein design
ALT 2024 Nobel Prize Laureate in Chemistry David Baker at his Seattle home shortly after learning he had been awarded a Nobel Prize. Photo by Ian Haydon, UW Medicine Institute for Protein Design.
Fred D. Mast retweeted
University of Washington biochemist David Baker has won the 2024 Nobel Prize in Chemistry for his pioneering work designing new proteins that can neutralize viruses, target cancer cells, and more.
Read more from @uwmedicine: go.uw.edu/2024NobelPrize
#NobelPrize #GoHuskies
Fred D. Mast retweeted
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Chemistry with one half to David Baker “for computational protein design” and the other half jointly to Demis Hassabis and John M. Jumper “for protein structure prediction.”
Fred D. Mast retweeted
BREAKING NEWS
The Royal Swedish Academy of Sciences has decided to award the 2024 #NobelPrize in Physics to John J. Hopfield and Geoffrey E. Hinton “for foundational discoveries and inventions that enable machine learning with artificial neural networks.”
I might be biased, but John is an excellent choice for Editor-in-Chief of MBoC. The future of this flagship cell biology journal looks bright!
ascb.org/society-news/ascb-a…
Fred D. Mast retweeted
ASCB announces John D. Aitchison, PhD, as the new Editor-In-Chief of its flagship journal, Molecular Biology of the Cell (MBoC), starting Jan 1, 2025. Dr. Aitchison's extensive research and editorial experience will help advance MBoC's legacy.
Read more: ascb.org/society-news/ascb-a…
ASCB Announces John Aitchison as New Editor-In-Chief for its Flagship Journal MBoC ascb.org/society-news/ascb-a…
Fred D. Mast retweeted
GOLD FOR CANADA 🇨🇦
SUMMER MCINTOSH HAS DONE IT
The 17-year-old swimming sensation Summer McIntosh wins her first Olympic gold medal. Her second medal of the Games.
She’s the first Canadian woman to win Olympic gold in the 400m individual medley.
Late night infomercials will have a field day with this… 🤦♂️
The rat with the big balls and the enormous penis – how Frontiers published a paper with botched AI-generated images
@FrontiersIn
scienceintegritydigest.com/2…
Fred D. Mast retweeted
Check out this great work led by @BarakRaveh, a first of its kind, integrative spatiotemporal map of the NPC explains the main molecular mechanisms underlying nuclear transport! A NCDIR @IntActOme special with our friends @salilab_ucsf, @DavidCowburn1 and @TheVillaLab
New year, new manuscript! Our work on mapping transport between the nucleus and the cytoplasm is now on BioRxiv, and it's time to embark on a journey through the nuclear pore complex. Nuclear what? Bear with me!
biorxiv.org/content/10.1101/…
This is a really enjoyable historical perspective from Edmond Fischer on his discovery, with Edwin Krebs, of Reversible Protein Phosphorylation as a Regulatory Mechanism.
#iBiology ibiology.org/cell-biology/re…
Fred D. Mast retweeted
Learn about #Nanobodies and their diverse #applications in highly effective #therapeutics through @bioprotocolbyte #webinar on synergistic nanobody combinations against SARS-CoV-2: bio-protocol.org/webinar/det…
by @FredDMast with Peter C. Fridy and Natalia Ketaren.
#bioprotocol
Fred D. Mast retweeted
@bioprotocolbyte Webinars turn one! 🥳
A year filled with incredible milestones:
🌍 5,861 registered users from 89 countries
📽️ 784 mins of free live streaming
💬 246 mins of live discussions
Register for past and upcoming webinars⬇️
bio-protocol.org/webinar
Fred D. Mast retweeted
The discoveries by Katalin Karikó and Drew Weissman – awarded the 2023 #NobelPrize in Physiology or Medicine – were critical for developing effective mRNA vaccines against COVID-19 during the pandemic that began in early 2020.
Through their groundbreaking findings, this year’s laureates have fundamentally changed our understanding of how mRNA interacts with our immune system. They have contributed to the unprecedented rate of vaccine development during one of the greatest threats to human health in modern times.
ALT A blue background with COVID-19 virus and a yellow strand of modified mRNA. Also shown is the chemical structure of pseudouridine, an RNA base that was important in the prize-awarded discovery. The graphic represents the 2023 Nobel Prize in Physiology or Medicine awarded to Katalin Karinkó and Drew Weissman who received the Nobel Prize in Physiology or Medicine for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
Fred D. Mast retweeted
“Ten years ago I was kicked out and forced to retire.”
Our new medicine laureate Katalin Karikó (@kkariko) told us how much it means to be awarded the Nobel Prize after a scientific career that has been full of challenges.
Ten years ago, Karikó was still doing all her experiments by hand but today she has been awarded the medicine prize for her research on mRNA, which led to the development of COVID-19 vaccines.
Listen now:
Fred D. Mast retweeted
BREAKING NEWS
The 2023 #NobelPrize in Physiology or Medicine has been awarded to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19.
