Dr. Joachim Frank's lab, Columbia University Medical Center.

New York, USA
Joined July 2019
sciencedirect.com/science/ar… Our Cell paper appeared today: "Time resolution in cryo-EM using a PDMS-based microfluidic chip assembly and its application to the study of HflX-mediated ribosome recycling"
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.@Columbia Prof @joachimfrank receiving his @NobelPrize from H.M. King Carl XVI Gustaf of Sweden at the Stockholm Concert Hall, 10 December 2017. #NobelPrize #NobelPrize2017 #CryoEM
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“This paper is the first comprehensive description of our highly successful time-resolved cryo-EM technology, combined with a detailed account of the most recent results obtained with this technique in studying the molecular mechanism of HflX-mediated ribosome recycling.”
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authors.elsevier.com/c/1iSQ3… From Frank lab, a Cell paper today on time-resolve cryo-EM (TRCEM) method, with new chip design + biol. application: short-lived intermediates of the recycling process ...... Thanks to @OliBClarke @LomvardasLab for early postings.
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-- New chip, described in detail + biol. application: intermediates of the recycling process, at 10, 25, 140 ms, with the ribosome opening up like a clamshell while bridges are severed, one by one.
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Thanks to @FrankLabCUMC & @adesgeorges for their efforts in educational outreach during our annual winter course. They are training the next generation of cryoEM practitioners. @SEMC_NYSBC: Providing #cryoEM expertise & resources for understanding molecular & cellular structures
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Check out some of the great pictures that just came in from Professor Joachim Frank's recent 80+ Birthday symposium! (via @ColumbiaMed @Columbia_Bio)
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Thank you Consul General David Gill @GermanyNY and Ms. Sheila Shrivastava for inviting us on behalf of @UniCologne to the stimulating conversation last night with two (!) @NobelPrize Laureates Prof. Martin Chalfie & Prof. @joachimfrank, & @ARDnewyork's @AntjePassenheim!
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Consul General Gill hosted a salon night with two Nobel laureates in cooperation with @lindaunobel. The highlight of the evening was a conversation with Nobel laureates Martin Chalfie and @joachimfrank moderated by @AntjePassenheim.
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The hard-working @RubinsteinJohn lab @SickKidsNews is at it again! The newly released raw data of empiar.org/10874 reveals endogenous mammalian V-ATPase interactions by #cryoEM. Published @LiSciAlliance (doi.org/10.26508/lsa.2022015…). #EMPIAR
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Amazing ventilation yesterday at #JF80 all day, both in the auditorium and in the coffee break/lunch room. CO2 levels w/Aranet4. Left my hotel room, right taxi ride (!) end of day. Those levels are very good. Kudos to the organizers on wonderful science and a safe environment!
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The whole group at Joachim Frank’s 80+ Birthday Symposium! Happy Birthday, Joachim (@joachimfrank)! #JF80+
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Incredible line-up of talks to celebrate Joachim Frank’s 80+ birthday today @ColumbiaPS. Peter Moore just gave a captivating survey of ribosome work over the decades, starting with 1950s images of rough ER, to early crystal structures, to CryoEM. Crazy how far the field has come
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