@FilomeniL

Electrons can provide energy and produce cell damage. We study the complexity and beauty of redox biology, with a major focus on protein S-nitrosylation.

 Denmark
cancer.dk/research/dcrc-research/redox-biology/
Joined June 2020
  • Tweets145
  • Following132
  • Followers106
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New article uncovers interesting crosstalk between #histone acetylation and RNA methylation modification on layer of #epigenetic regulation in #pancreatic cancer! More in :📍@oncogenejournal Link : nature.com/articles/s41388-0…
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Finanziamento USA per un progetto di ricerca di “Tor Vergata”⁩ ⁦@BiologiaUniRM2⁩ web.uniroma2.it/it/contenuto…

Finanziamento USA per un progetto di ricerca di “Tor Vergata”

web.uniroma2.it
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Online Now: Determinants and outcomes of mitochondrial dynamics dlvr.it/SkW0Yf

Determinants and outcomes of mitochondrial dynamics

Quintana-Cabrera and Scorrano review the molecular mechanisms regulating mitochondrial morphology and ultrastructure and discuss how they have an impact on mitochondrial physiology.

cell.com
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🔊Our latest paper is out in ⁦⁦⁦⁦⁦@NatureComms⁩‼️ #Mitochondria #NDI #OxygenSensing ⁦@ibis_sevilla⁩ ⁦@unisevilla⁩ ⁦@ciberned⁩ ⁦⁩ ⁦⁦⁦⁦@NorthwesternU⁩ 👇🏻👇🏻👇🏻 nature.com/articles/s41467-0…

Transgenic NADH dehydrogenase restores oxygen regulation of breathing in mitochondrial complex...

Nature Communications - Activation of breathing during hypoxia is abolished in mice lacking mitochondrial complex I in carotid body chemoreceptors, however the specific contribution of...

nature.com
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New #JITC article: Ambra1 modulates the tumor immune microenvironment and response to PD-1 blockade in melanoma bit.ly/3ZgrEep @melanomateam
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Plexin-B3 expression stimulates MET signaling, breast cancer stem cell specification, and lung metastasis dlvr.it/SkCrJ2
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Pyruvate dehydrogenase fuels a critical citrate pool that is essential for Th17 cell effector functions dlvr.it/SkBBZM
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Una gran alegría que mi mentor Prof. Santiago Lamas ha sido investido Doctor honoris causa por la Universidad de la República, de Uruguay 👏👏 @Udelaruy @fmedoficial @ceinbio @CBMSO_CSIC_UAM @CSIC
fmedoficial@fmedoficial1 Mar 2023
Se está llevando a cabo en nuestra facultad la conferencia del Prof. Dr. Santiago Lamas, quien recibirá el Título: Honoris Causa de la Facultad de Medicina.
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In this Issue: Optogenetically opposing age-related decline in mitochondrial membrane potential leads to increased #healthspan and #lifespan in C. elegans => Mitochondrial charge = key regulator of biological aging @mitobrandon @UWMedicine @URNeuroscience doi.org/10.1038/s43587-022-0…
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There are 283 new PDB entries this week, including this structure (7u1t) of the DNA-binding domain of Epstein-Barr nuclear antigen 1 bound to DNA. View all new entries at PDBe.org/latest
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Some of you may have seen an edited version of our video circulating recently, here is the original! Filopodia extension in a migrating fibroblast. #cell #biology #education #animation @rainmaker1973
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🗞 Our February issue is out! Read about #Alzheimer disease, #sensecence, #mitochondrial rejuvenation, #GDF11 in depression and memory, #progeria, and much more. 🎨 Cover image from Sciepro/Science Photo Library/Getty and designed by Lauren Heslop. nature.com/nataging/volumes/…
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Most downloaded papers @NIOX_Journal @elsbiomedchem: Nitric oxide, aging and aerobic exercise: Sedentary individuals to Master's athletes By Oliver M. Shannon @Oli_Shannon et al, from @UniofNewcastle @lborouniversity @CUBoulder sciencedirect.com/science/ar…
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Starting tomorrow! - Gordon Research Seminar and Gordon Research Conference on Molecular Mechanisms of Nitric Oxide Signaling in Health and Disease. February 11-12, 2023 (GRS) and February 12-17,2023 (GRC) in Ventura (CA). @GordonConf grc.org/nitric-oxide-confere…
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FilomeniLab retweeted
Tobias Dick@RedoxDKFZ7 Feb 2023
"In the Pipeline" @ScienceMagazine: Derek Lowe reflects on “Weird Little Sulfur Groups”, inspired by our new paper on protein persulfidation @nchembio nature.com/articles/s41589-0… science.org/content/blog-pos…

3-Mercaptopyruvate sulfur transferase is a protein persulfidase

Nature Chemical Biology - Mercaptopyruvate sulfur transferase (MPST) is revealed as a protein persulfidase that acts directly on numerous and diverse target proteins, revealing potential origins of...

nature.com
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FilomeniLab retweeted
Spirochrome@spirochrome8 Feb 2023
Mitotracker red CMXRos quickly damages mitochondria (= rounded & swollen) after 200 Hessian SIM frames while PKmito™ RED keeps them happy for much, much longer! Get your PKmito probes with 50% discount now: spirochrome.com/products/pkm… Movie from : pubs.rsc.org/en/content/arti… #PKmito
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Your cell is a factory that works 24/7: #biology by WEHImovies
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2/2 Thanks to all the contributors from @cancer_dk , @LabLarsen @ZiznyoGal @danielgomcab #drcgroup and from @UCPH_health , @GregersenLab
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FilomeniLab retweeted
Sharon Glynn@shazglynn16 Jan 2023
Replying to @NIOX_Journal
Check out great articles on effects of chronic NO exposure on prostate cancer development. NO and PDT response. NO scavenging mechanisms by hemin. NO and the liver tumor microenvironment. H2S and nitrite in protection against MI. Denitroyslation in rhabdomyosarcoma. @FilomeniL
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We are very excited to share our latest study just published on @CellReports! "GSNOR deficiency promotes tumor growth via FAK1 S-nitrosylation" sciencedirect.com/science/ar…
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