Fiorela Duenas, MD retweeted
Kleine DNA-Ringe können das Tumorwachstum antreiben. Werden sie aber in zellulären „Gefängnissen“ – den Mikronuklei – eingeschlossen, verlieren sie ihre Wirkung. Das zeigen Forschende der #CharitéBerlin & des Max Delbrück Center in einer aktuellen Studie: charite.de/forschung/themen_…
Fiorela Duenas, MD retweeted
A Multipart Phase 1 Study to Assess Safety and Pharmacokinetics of Ibuzatrelvir in Healthy Participants and Dose Selection for a Dose‐Ranging Study — by Ravi Shankar Prasad Singh et al.
#CTSjournal #ASCPTjournals
👉 tnyp.me/1tc9wR0n/x
Fiorela Duenas, MD retweeted
📣 Trabajas o quieres trabajar en investigación clínica, apúntate a nuestros cursos #UAM_Medicina reconocidos con 2 ECTS
Fiorela Duenas, MD retweeted
Researchers at @berkeleyMCB demonstrated that strong and sustained type I IFN responses specifically and cell intrinsically impair responsiveness to #IFNγ to cause susceptibility to #MycobacteriumTuberculosis. 🫁
Learn more: bit.ly/4cNybpV | #OpenAccess
Fiorela Duenas, MD retweeted
📝 #JAMAReview: #LiquidBiopsy using circulating #tumor #DNA can help guide care in #Cancer by identifying gene variants associated with treatment selection, monitoring treatment response, and detecting minimal residual disease after therapy.
Detectable circulating tumor DNA after curative-intent treatment was associated with recurrence and poorer survival across multiple cancer settings, often before progression was evident on imaging.
ja.ma/4dFgtVU
Fiorela Duenas, MD retweeted
1/6 🧵🧬
📢 Nueva publicación de @FC_HULP @HospiLaPaz en Frontiers in Pharmacology. En niños con enfermedad hematológica y riesgo de aspergilosis, el genotipado CYP2C19 previo al voriconazol redujo de forma significativa la infradosificación precoz. Ensayo VORIGENIPHARM👇
Fiorela Duenas, MD retweeted
New Research: Editorial: Emerging targeted and immunotherapeutic strategies in oncology: from solid tumors to hematologic malignancies frontiersin.org/articles/10.… #FrontiersIn #Pharmacology
Fiorela Duenas, MD retweeted
Using single-cell immune profiling, scientists from the University of Osaka analyzed T cells from #supercentenarians and found that cytotoxic T lymphocytes begin to expand around the age of 100, characterized by sequential CD27/CD28 loss without exhaustion. bit.ly/4y8im5t
📖: @CellReports
Fiorela Duenas, MD retweeted
🧬 Una terapia innovadora que busca actuar en la puerta de entrada de muchas infecciones.
🏥 El #HospiLaPaz pone en marcha el primer ensayo en humanos con terapia celular intranasal para reforzar las defensas del sistema respiratorio.
🔗 c.madrid/6rc8u
#SomosLaPaz
Fiorela Duenas, MD retweeted
#OSUWexMed health experts explain the crucial role bone marrow plays in producing blood cells and supporting your immune system every day. 🩸 health.osu.edu/health/cancer…
Fiorela Duenas, MD retweeted
Working closely with your care team to gradually lower opioid doses ensures a safe reduction process while minimizing uncomfortable withdrawal symptoms.
Fiorela Duenas, MD retweeted

The Nobel Prize@NobelPrizeJul 25
Sweden
SwedenConnected via Sweden App StoreAccount-level information, not a live location or per-post device.
“I have four brothers and I’ve jumped into all sorts of things during my life. Learning new things has always been fun for me.”
2018 chemistry laureate @francesarnold received the #NobelPrize for her work using evolution to make better enzymes. Today she celebrates her birthday!
Fiorela Duenas, MD retweeted
New Research: Oral metal immunotoxicity in rodents: a recoverability-aware systematic review and within-study quantitative reanalysis of splenic SRBC-TDAR frontiersin.org/articles/10.… #FrontiersIn #Toxicology
Fiorela Duenas, MD retweeted
The first clinical guidelines for #CKMSyndrome provide new recommendations for staging, diagnosis, and management of overlapping metabolic, kidney, and cardiovascular risk in adults.
JAMA Medical News Associate Managing Editor Kate Schweitzer and News Director Jennifer Abbasi discuss how the guidelines call for regular metabolic risk assessment—including waist circumference and eGFR—and highlight the importance of team-based, coordinated care for patients with multisystem involvement.
🎧 Listen now: ja.ma/4wOL0rF
Fiorela Duenas, MD retweeted
New in @FrontiersIn: A framework for referring infants with positive genetic newborn screening results to the appropriate European Reference Network, supporting timely and equitable rare disease care across Europe. 🧬
🔗 frontiersin.org/journals/pub…
Fiorela Duenas, MD retweeted
We've written about AI-induced physician deskilling that has already surfaced
thelancet.com/journals/lance… @tberzin
AI-induced never-skilling among newly trained doctors, while not yet proven, is a serious concern that needs to be addressed @NatureMedicine @nliulab
nature.com/articles/s41591-0…
Fiorela Duenas, MD retweeted
💊 Hoy, en el Día Internacional del Ensayo Clínico, recordamos que algunos tratamientos no solo cambian el curso de una enfermedad. También transforman la forma de vivir, de mirar al futuro e incluso de celebrar la vida.
Detrás de estos avances hay años de investigación, desarrollo y el compromiso de muchas personas que trabajan para hacer posible la llegada de nuevos medicamentos.
En este proceso, los ensayos clínicos desempeñan un papel esencial.
Hoy nace +ensayos, una plataforma que permite comprender, de forma clara y cercana, qué son los ensayos clínicos, cómo se autorizan, cómo funcionan y por qué son clave para seguir avanzando en innovación biomédica.
🔎 Conoce más sobre el valor de la investigación clínica: masensayos.com/?utm_source=m…
#MásEnsayos #InvestigaciónClínica #EnsayosClínicos
Fiorela Duenas, MD retweeted
🔬 Somos motor de investigación clínica:
🧪 Ensayos clínicos
🌐 Investigación académica @SCReN_Platform
💊 Terapias avanzadas
🇪🇺 Liderazgo proyectos europeos
Especialidad transversal, científica y con futuro 🚀
🔗 comunidad.madrid/hospital/la…
#ElijoLaPaz #FarmacologiaClinica
Fiorela Duenas, MD retweeted
🩺💊 ¿Eligiendo especialidad MIR?
En @HospiLaPaz hacemos Farmacología Clínica con impacto real:
🧬Farmacogenética e individualización terapéutica
👁️Farmacovigilancia y seguridad del paciente
☠️Toxicología Clínica 24/7
🔬Investigación clínica de impacto
#MIR2026 🧵👇



























