@EricGSun

MD/PhD Student @TriIMDPhD | Ventura Lab | Previously @yalegenetics @theNCI | he/him/his

 Washington D.C. | New York
Joined April 2015
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18Media
Seeing Is Believing: Intercellular Transfer of DNA between Human Cells—this In the Spotlight commentary by Eric G. Sun and Andrea Ventura from the August 15 issue highlights a recent Cell article by Elizabeth G. Maurais et al. doi.org/10.1158/0008-5472.CA… @EricGSun
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Corey N Cunningham@CNFXCJul 7
Excited to share our new preprint from @RutterLab, identifying a melanosomal tyrosine transporter! biorxiv.org/content/10.64898…

SLC16A6 is a tyrosine transporter for the melanosome

Cells enable specialized metabolism by compartmentalizing metabolic pathways into distinct organelles, which requires the membrane transport of metabolites. In melanocytes, the amino acid tyrosine is...

biorxiv.org
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Seeing is Believing: Intercellular Transfer of DNA between human cells doi.org/10.1158/0008-5472.CA… Congrats to the @PeterLyLab on a spectacular paper, describing an extraordinary mechanism!
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A Yale study finds the protein #METTL7A triggers early resistance to #osimertinib by reshaping DNA architecture. Targeting METTL7A could help block resistance before it starts. #lungcancer #adenocarcinoma yalecancercenter.org/news-ar… @SmilowCancer @NatureSMB
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Excited to share this work with @RebeccaStarble (please see tweetorial!) Very thankful to our funders and collaborators especially @SStevenWang, Politi Lab, Wang Lab @ UCR, and @nitinroper
Rebecca Starble@RebeccaStarble27 Oct 2025
Excited to see my PhD work out! Here, we find an unexpected epigenetic mechanism that regulates oncogene amplification to promote tyrosine kinase inhibitor resistance in lung adenocarcinoma. Tweetorial below! ⬇️ nature.com/articles/s41594-0…

Epigenetic priming promotes tyrosine kinase inhibitor resistance and oncogene amplification

Nature Structural & Molecular Biology - Starble, Sun, and colleagues identify an epigenetic priming mechanism that promotes oncogene amplification in acquired resistance to tyrosine kinase...

nature.com
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Excited to share a story spearheaded by the incredible @rob_seb_ where we describe a fundamental genome maintenance mechanism linking DNA replication with double-strand breaks @Nature! nature.com/articles/s41586-0… 🧵👇 1/n
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We are especially thankful to @VartakSupriya, @POberdoerffer, and Andrew Xiao for feedback and discussions. I am incredibly grateful to @RebeccaStarble and @Tyler_B_Jensen for letting me bother them about all kinds of bioinformatics questions 😅 12/n
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Lastly, a special shoutout to @dave_sturgill, @jakelee0711, and @jmchan88 who have and continue to inspire me to combine computation with wet-lab biology 13/n
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Things I wish more people knew about doing science in the US (thread):
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Out today in @Nature, we describe a method to engineer ecDNAs! Congrats to @prade90, Minsi, Rui, and Melissa!
Andrea Ventura@aventura7118 Dec 2024
1/ 🚨New paper on ecDNAs from our lab! We reveal a strategy to engineer extrachromosomal DNA (ecDNA) amplifications in cells & mice. Let's dive in! 🧵👇 nature.com/articles/s41586-0…

Engineered extrachromosomal oncogene amplifications promote tumorigenesis

Nature - Large extrachromosomal DNAs are engineered using a CRISPR- and Cre–loxP-based approach and shown to drive cancer in mouse models, with potential applications in determining the role...

nature.com
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