South San Francisco-based biotech company specializing in antibody detection.
South San Francisco, CA
Joined April 2016
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We will be attending the American Diabetes Association's 83rd Scientific Sessions this weekend in San Diego! Come visit our team at Booth #1815.
#ADA2023
#type1diabetes
Congratulations to Enable cofounder @CarolynBertozzi for winning the Priestley Medal, the highest award offered by the American Chemical Society!
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Enable Biosciences retweeted
After launching 7 companies (Thios, Redwood, @EnableBio @Palleon_Pharma @vennbio @gracescience @OliluxB @LyciaTx) in 12 years, @CarolynBertozzi the prolific biotech business founder says she’s always on the lookout for problem-solving opportunities @cenmag
cen.acs.org/biological-chemi…
Enable Biosciences retweeted
It's our honour to announce that Professor Åke Lernmark is the recipient of the EASD Claude Bernard Prize 2023, recognising his innovative leadership and lifetime achievements in #diabetes #research.
Congratulations @AkeLernmark👏, we look forward welcoming you at #EASD2023
Pere Santamaria of Parvus Therapeutics describes tolerogenic peptide-mhc coated nanoparticles ("navacims").
Promote differentiation of antigen-specific autoreactive t cells into treg-like cells.
1/x
#ids2023
Professor Anath Shalev from @UofAlabama describes repurposing of TXNIP inhibitor verapamil for beta cell protection.
Mechanism unclear, but verapamil treatment in new onset T1D causes downregulation of autoantigen chromogranin a.
1/x
#ids2023
Anti inflammatory signatures observed w varapamil treatment, as well as downregulation of various HLAs.
Screened for novel TXNIP inhibitors, oral treatment w candidate TIX100 rescues mice from obesity- and STZ- induced diabetes.
2/x
#ids2023
Ezio Bonifacio opens autoantibody screening strategy session.
99% specificity may sound good, w low prevalence diseases there will still be a surplus of false positives.
Need to follow up w more specific assays, while taking into account assay-specific behavior.
1/x
#IDS2023
Screening assays should emphasize sensitivity over specificity to pick up all true positives.
Validation assays should emphasize specificity over sensitivity to ensure low false positive rates.
Both assays shld use small volume samples for ease of collection and analysis.
2/x
Annette Ziegler describes a subset of stage 1 diabetes with >50% chance of progressing to stage 3 type 1 diabetes in the next two years.
This higher-risk stage 1b cohort might be viewed similarly to stage 2 individuals.
3/x
#ids2023
@umiamimedicine Professor Jay Skyler gives an overview of the past, present, and future of prevention/delay studies for type 1 diabetes.
T-cell inhibition therapies show success, but it's hard to identify Stage 2 patients for trials and clinical care.
1/x
#ids2023
Anti-cytokine therapies show success, but require continuous infusion to maintain efficacy.
Suggests a 3-prong combination therapy approach to T1D prevention/delay by modulating the immune system while promoting beta cell health.
2/x
#ids2023
We are a Silver Sponsor at #ids2023 in Paris!
Come by and:
1. Visit our booth to learn about ADAP T1D Autoantibody Assays and more.
2. Visit us at Poster #38 on Friday.
Hope to see you in Paris!
#T1D
#Paris
#immunology
Enable Biosciences retweeted
Are you going to #IDSParis2023 this week? If so, join @WIELDvoice on Thursday before the gala for an informal gathering & to learn more about who we are & what we do.
Enable Biosciences retweeted
If you are diagnosed with type 1 diabetes, your risk of getting celiac disease increases tenfold.
Here's more about the symptoms.
beyondtype1.org/celiac-disea…
Did you know?
Enable Biosciences' T1Define Type 1 Diabetes test has been validated with thousands of samples with over 8 peer-reviewed publications.
#t1dlookslikeme
#t1d
#type1diabetes
Enable Biosciences retweeted
Screening for type 1 with @JDRF's T1Detect prevents life-threatening DKA at diagnosis.
It lets you catch T1D early so you can enroll in trials that delay diabetes onset.
It's one more thing @GingerVieira can do for her kids. #SeeTheSigns beyondtype1.org/screening-my…
Enable Biosciences retweeted
Why are we so passionate about helping people #SeeTheSigns? Because DKA is life-threatening, and getting a correct diagnosis shouldn't come down to luck. beyondtype1.org/one-of-the-l…
“To get an early diagnosis is so critical. If you can catch type 1 before DKA, you’ve saved yourself the possibility of brain damage... And so that early recognition is so vital, not just because of the scariness of DKA, but because of the unknown that comes with it.”
Kycie Terry passed away at age 5 from complications caused by a missed type 1 diabetes diagnosis.
Her death was preventable.
Her story has saved lives. #SeeTheSigns beyondtype1.org/kycie-terry/
