Efe Begar (@EfeBegar) profile picture

Efe Begar

@EfeBegar
 İstanbul, Türkiye
Joined August 2015
  • Tweets17
  • Following53
  • Followers43
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Photo by Efe Begar (@EfeBegar)
Exciting new preprint alert! Our latest research is a tour de force exploring the biology of centriolar satellites, membrane-less organelles essential for development and physiology. Below tweets summarize our findings; full paper here 👇 biorxiv.org/content/10.1101/…
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
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Centriolar satellites are dynamic membrane-less organelles that assemble via a hierarchical pathway biorxiv.org/content/10.1101/… #biorxiv_cellbio
Centriolar satellites are dynamic membrane-less organelles that assemble via a hierarchical pathway

Centriolar satellites are dynamic membrane-less organelles that assemble via a hierarchical pathway

Centriolar satellites (CS) are ubiquitous, membrane-less organelles recognized for their dynamic organelle crosstalk, plasticity, diverse functions and links to developmental and neuronal diseases....

biorxiv.org
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Sorry to miss #cellbio2024 as my 5-month-old isn't quite ready for transatlantic flights, But Cytolab is still represented! Don't miss @EfeBegar's microsymposium talk & poster on centriolar satellites and @b_asakturan's poster on non-ciliary functions of ciliopathy proteins.
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
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We are happy to contribute to a new paper by @KaplanOLab, which generated the Ciliogenics database for predicting novel ciliary genes. @EfeBegar used localization and loss-of-function experiments to validate new ciliary proteins in mammalian cells. @NAR_Open
Oktay I. Kaplan (@KaplanOLab) profile pictureOktay I. Kaplan@KaplanOLab13 Jul 2024
Our paper "CilioGenics: an integrated method and database for predicting novel ciliary genes" is out in @NAR_Open ! academic.oup.com/nar/advance… A preprint of this work was posted in April 2023.
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Our latest review article on navigating the biology of centriolar satellites is out in ⁦⁦⁦@FEBSJournal⁩! It focuses on their diverse functions and mechanisms across cells, organisms and their links to disease. Congratulations @EfeBegar⁩&Ece! febs.onlinelibrary.wiley.com…
FEBS Press

FEBS Press

This review explores the enigmatic centriolar satellites, which are crucial cellular structures first identified in vertebrate cells. We highlight their roles – from forming cilia to responding to...

febs.onlinelibrary.wiley.com
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Please #RT! We are very pleased to announce that registration for #EMBOCentrosomes is now live- meetings.embo.org/event/23-c…! Join us in Istanbul September 26-29 2023 for the largest #centrosome meeting- great lineup of speakers & plenty of talk slots to be selected from abstracts.
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
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2 times ERC winner! Assoc. Prof. Elif Nur Fırat Karalar from the Department of Molecular Biology and Genetics received her 2nd ERC starting grant to study Spatiotemporal regulation of centriolar satellite homeostasis. We wholeheartedly congratulate her exceptional achievement.
Image from Koç University College of Sciences (@KocSciences)
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Today, @CaydasiLab and I just submitted the application for the #Centrosomes2023 "Centrosomes in Development, Disease and Evolution" workshop that will take place in Istanbul between 26-29th September in 2023. Fingers crossed for a positive evaluation of our application to @EMBO!
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The ciliopathy-linked protein CCDC66 is only known for its ciliary functions. A new study in #PLOSBiology reveals that CCDC66 also has extensive non-ciliary functions in regulating #mitosis and #cytokinesis @CytoLabKoc plos.io/3yOwzY8
Image from PLOS Biology (@PLOSBiology)
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📄 ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium content regulation ✏️ By Fatmanur Tiryaki, Jovana Deretic and Elif Nur Firat-Karalar @CytoLabKoc @kocuniversity 🔗 buff.ly/3c4rm71 #centrosome #ENKD1 #Hedgehogsignaling
Image from The FEBS Journal (@FEBSJournal)
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It feels amazing to finally share that my first first-author paper is now online as a preprint! 🥳 biorxiv.org/content/10.1101/… This work is done when I was a master student in @CytoLabKoc in collaboration with Jovana Deretic. Read below our main findings 👇
The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule...

The ciliopathy protein CCDC66 controls mitotic progression and cytokinesis by promoting microtubule...

Precise spatiotemporal control of microtubule nucleation and organization is critical for faithful segregation of cytoplasmic and genetic material during cell division and signaling via the primary...

biorxiv.org
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ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium content regulation dlvr.it/SHl15v
Image from Cilia Papers (@cilia_biblios)
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We @CytoLabKoc @CaydasiLab would love to host the next #EMBOcentrosomes in İstanbul at Koc University. The campus is located on a beautiful hillside overlooking the Black Sea. There are direct flights from most countries to İstanbul.
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
Image from Elif Nur Firat-Karalar (@CytoLabKoc)
LeritLab (@LabLerit) profile pictureLeritLab@LabLerit12 Oct 2021
Time to vote! Where do you want the next #EMBOcentrosomes meeting to be? Log in to whova and cast your vote. Personally, I’d be happy to visit all proposed locations! 🇨🇭🇪🇸🇹🇷
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ENKD1 is a centrosomal and ciliary microtubule-associated protein important for primary cilium assembly and Hedgehog signaling biorxiv.org/cgi/content/shor… #biorxiv_cellbio
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Proud lab members! We congratulate our PI Elif Nur Fırat Karalar @CytoLabKoc for receiving Sabri Ülker Science Award 🥇
Image from Umut Batman (@umutbatmann)
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