Biophysics, biosensors and drug discovery. Marie Curie Industry fellow @beactica & @UU_University.
Uppsala, Sverige
Joined May 2011
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Ted FitzGerald retweeted
15 PhD positions in an MSCA doctoral training network available. The network is about targeting RNA with small molecules (TargetRNA) and the positions span from molecular biology, chemistry, and computational design to structural biology and microbiology. uib.no/en/targetrna
Fragment screening beyond state of the art @UUBiochem ! Identifying hits based on kinetic parameters rather than affinity 🚀Check out how we used a multiplexed GCI biosensor based approach to identify novel fragments targeting SMYD3 & orthogonally validated with XRC. @rsc_medchem #FBDD #Biophysics #GCI #Biosensors
pubs.rsc.org/en/content/arti…
Ted FitzGerald retweeted
I am looking for a PhD student to work on structure-based design of RNA ligands.
This is great opportunity to combine working on a challenging research project with enjoying the outstanding natural beauty of Norway.
#PhDposition #RNA #SBDD #Norway
jobbnorge.no/en/available-jo…
Ted FitzGerald retweeted
The first prime editing clinical trial has been cleared by @US_FDA to begin: prime editing of HSCs to treat chronic granulomatous disease (CGD). Congratulations to @PrimeMedicine on achieving this key milestone only 4.5 years after we published the first prime editing paper.
We are pleased to announce that #FDA has cleared our IND application for PM359 for the treatment of chronic granulomatous disease (CGD), enabling Prime to initiate its Phase 1/2 clinical trial in the US. Details: investors.primemedicine.com/… $PRME
Ted FitzGerald retweeted
Do you face challenges in investigating G-protein-coupled receptors (GPCRs)? 🤔
Join Dr. Edoardo Fabini from Evotec for a free online webinar on April 9th at 3 pm CET to overcome these challenges.
Register now 👉 bit.ly/3V9Dx6W
#drugdiscovery #gpcr #fbdd
Ted FitzGerald retweeted
A round-up of the @RSC_BMCS conference in Cambridge UK #Fragments24
practicalfragments.blogspot.…
@macinchem characterized fragments from >300 papers, sparking conversations around routes to covalency (@CossarPeter), thermodynamics, binding sites versus starting points, and much more
Ted FitzGerald retweeted
We're recruiting: Science Coordinator (Jr / Sr) to @asap_discovery in @XChem_DLS team at @DiamondLightSou. See vacancies.diamond.ac.uk/vaca… - deadline Jan 15.
For scientists who're done postdocing, but like large collabs, coordinating, writing, outreach - ping me if any questions.
Ted FitzGerald retweeted
A how-to guide for fragment screening against tough proteins by SPR. Nine constructs tested, quality controls in place, hits against all.
@HelenaDanielson + other biophysical luminaries @UUBiochem @UU_University
practicalfragments.blogspot.…
Ted FitzGerald retweeted
The benzene ring is present in the structures of more than 500 FDA-approved drugs. Bicyclo[1.1.1]pentane can efficiently replace the benzene ring, improve the solubility and metabolic stability of compounds.
Try our bicyclo[1.1.1]pentane building blocks in your research!
Ted FitzGerald retweeted
We are looking for a postdoc / researcher to work on a project about using ML to improve scoring functions for molecular docking. We are located in beautiful #Norway. jobbnorge.no/en/available-jo… The position will be located at the @cbu_bergen #SBDD
Ted FitzGerald retweeted
Usuaris #CCiTUB participen en la demo "Grating Coupled Interferometry (GCI): El WAVEsystem i waveRAPID" a càrrec de Paralab Bio en col·laboració amb el laboratori d'Anàlisi d'Interaccions Moleculars del centre.
Moltes gràcies a tots els assistents!
bit.ly/3Hw2GBy
Ted FitzGerald retweeted
The next step in our @XChem_DLS and @asap_discovery journey. We had a fun day in the lab with @melissalmarx @GrosjeanHarold and @migueldanmoz for Creoptix training at the Research complex. Thank you @E_FitzG for the brilliant training and all the patience with UK traffic.
An important thread at an important time 🇺🇸
Ted FitzGerald retweeted
A new license signed btw. @HarvardTechXfer and @Alkem_Lab are bringing a Wyss-developed technology to the market to help the millions of people worldwide who suffer from diabetic neuropathy, foot ulcers, peripheral arterial disease, and more.
wyss.harvard.edu/news/alkem-…
Ted FitzGerald retweeted
Amazing news! Congratulations to Irishwoman Dr. Ann Kelleher on this incredible achievement! 🙌
Thrilled to share that Dr. Ann Kelleher is now @Intel executive vice president. So well-deserved with her many contributions including the turnaround of our Tech Dev organization this past year. intel.com/content/www/us/en/…
Ted FitzGerald retweeted
We report Optimization of Triarylpyridinone Inhibitors of the Main Protease of SARS-CoV-2 to Low-Nanomolar Antiviral Potency pubs.acs.org/doi/10.1021/acs… #COVID19 @YaleChem @YaleMed
Interested in FBDD ? Check out some of the latest work from the Danielson Lab @UUBiochem during @OGConferences next week. #FBDD #drugdiscovery – at Oxford, England
Are you interested in hit identification in Fragment Based Drug Discovery? 🧐🤓
Join us on June 3rd with @OGConferences for a Thought Leadership Session with @HelenaDanielson from @UU_University.
Register here: lnkd.in/dktxYT6
#kinetics #fragments #novelbiosensor
Ted FitzGerald retweeted
How do you get relevant conformational change information on your fragment library screening? 🧐
@E_FitzG and colleagues used #GCI with #SHG to provide full binding characterization of Acetylcholine Binding Protein to #fragments, click here and check it: rsc.li/3sdGwJr
