Lifelong RNA biologist with a lab full of CRISPR pros who are pro-CRISPR and pro-AntiCRISPR @RTI_UMassChan
Worcester, MA
Joined February 2020
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ErikSontheimerLab retweeted
The RTI's Anastasia Khvorova elected to the National Academy of Inventors Fellows Class of 2022!
The new class @AcadofInventors is comprised of 169 prolific academic innovators from over 110 research universities and research institutes worldwide: ow.ly/TTy950LWi2k
ALT Anastasia Khvorova elected to the National Academy of Inventors Fellows class of 2022!
ErikSontheimerLab retweeted
We wish #LaskerAward winner Victor R. Ambros a happy birthday! By studying the microscopic worm #Celegans, he discovered that small RNAs are key regulators of gene expression. @UMassChan #modelorganism ow.ly/Ak7150CsW9p
ErikSontheimerLab retweeted
Proud to be at the top in the heart of New England: UMass Chan Medical School is on The Boston Globe’s 2022 list of the Top Places to Work in Massachusetts because of its collaborative, inclusive culture: bit.ly/3is9O83 #WhyUMassChan #workboston @BostonGlobeMag
ErikSontheimerLab retweeted
#HAE News: Today at @ACAAI, Intellia presented additional interim results from its ongoing Phase 1/2 study of NTLA-2002, an investigational, in vivo #CRISPR #genomeediting therapy for HAE. Learn more: bit.ly/3NZyH6H
This news makes my day 👏👏👏
Thank you to the HFSP Nakasone award, this is a great honor.
Stoked and humbled to be included in the same list as the amazing scientists who received this award in the past
hfsp.org/awardees/hfsp-nakas…
ErikSontheimerLab retweeted
"Efficient Homology-Directed Repair with Circular Single-Stranded DNA Donors"
Iyer S et al.... @ESontheimerLab Scot Wolfe
liebertpub.com/doi/10.1089/c…
I’m joining you on that island. As a reviewer, I’ve always found it as helpful as getting clubbed over the head.
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Take it from me: Tomás rocks
MD/PhD student Tomás Rodríguez restarted @UMassChan’s Latino Medical Student Association chapter in 2020. He established the optional Medical Spanish elective in collaboration with students from all three schools. #HispanicHeritageMonth @trodriguezUMMS @UMassMDPhD @UMassChanSOM
ALT MD/PhD student Tomás Rodríguez
🤜🏻🤛🏻
As @grunewaju notes in his summary, @ESontheimerLab also published similar findings about split prime editors in @NatureBiotech earlier this year: nature.com/articles/s41587-0…. 7/7
Great stuff Keith! 👏
Excited that the latest @JoungLab paper describing split #CRISPR prime editors is out online @NatureBiotech today. This work was led by @grunewaju, Bret Miller, @ReganSzalay with co-authors Peter Cabeceiras, Chris Woodilla @elizajaneholtz @Karl_Petri nature.com/articles/s41587-0… 1/7
🙏
Please also check out this fantastic @ESontheimerLab paper that was published in NBT recently, describing the "split-PE" discovery (and much more amazing stuff!) nature.com/articles/s41587-0…
Great work, Julian, congrats! (And from your previously tweeted photo: nice new digs in Munich 😉)
Boston RT party!🧬So excited about our #CRISPR prime editing work, out @NatureBiotech today – great @JoungLab team work w/ Bret Miller, @ReganSzalay, @johnASeed1, Chris Woodilla, @elizajaneholtz, @Karl_Petri & @JKeithJoung nature.com/articles/s41587-0…
Prior fellow from the mid-‘90s! Glad to stay connected
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ErikSontheimerLab retweeted
Learn more about who we are, what we do and why we do it: vimeo.com/749675163 #OneIntellia
ErikSontheimerLab retweeted
🚨New Publication🚨 from #SCGE PIs @ESontheimerLab and @ScotWolfe1 efficiently uses circular single-stranded #DNA for homology-directed repair liebertpub.com/doi/10.1089/c…
@UMassChan
@aamirmir09
@badillo160682
@raed_ibraheim
@K_Luk2
@zamore_lab
Great stuff Mo, @davidrliu, @_ShannonMMiller and team, congrats!
4/n We looked to Cas9 orthologs from other organisms as starting points. Nme2Cas9 from N meningitidis stood out. As characterized by @ESontheimerLab & others, this ortholog has natural activity on N4CC PAMs and (bonus for delivery!) is more compact than SpCas9 (1082aa vs 1368aa).
ErikSontheimerLab retweeted
Check out our overview of strategies to clone and sequence small RNAs which is the cover of this months @Curr_Protocols designed by the extremely talented @NATrigg
The latest issue of CP is out!
The cover highlights an Overview by @OliviaJCrocker
@NATrigg & @ColinConine (@ChildrensPhila and @Penn), who discuss how to design small #RNA cloning workflows in eukaryotes to capture specific small RNAs of interest.
➡️bit.ly/3eaHq8e
ErikSontheimerLab retweeted
The @somaticediting consortium launched the #SCGEToolkit, a platform housing #data generated from #SCGE studies: novel delivery systems, independent validation studies & effects of #GenomeEditing. Visit the toolkit and share your feedback at scge.mcw.edu/toolkit.
ALT SCGE Somatic Cell Genome Editing logo. Text on image, The Somatic Cell Genome Editing Program Toolkit. A publicly available platform housing data generated by the Somatic Cell Genome Editing Consortium.
Thank *you* @ColinConine, this authoritative piece will be very useful for a lot of people! 🙏
Thank you @aemonten and @Curr_Protocols for a smooth review and making the manuscript significantly better in the process. Also, @ESontheimerLab for inviting us to write it in the first place.