
ALT A flowchart showing the win-ratio analysis for death, hospitalization for heart failure, and quality-of-life improvement (first coprimary end point).

ALT Three graphs showing Kaplan–Meier estimates for prespecified events as adjudicated by the clinical-events committee at 3 years. Panel A shows freedom from death from any cause or hospitalization for heart failure (second coprimary end point), Panel B survival, and Panel C freedom from hospitalization for heart failure.

ALT Two bar graphs showing the severity of tricuspid regurgitation and New York Heart Association (NYHA) class. The bar graphs summarize the severity of tricuspid regurgitation as adjudicated by the echocardiographic core laboratory (Panel A) and the severity of heart failure as defined by the NYHA functional class (Panel B) at baseline, 30 days, and 1 year in both trial groups.

ALT Three graphs showing Kaplan–Meier estimates for prespecified events as adjudicated by the clinical-events committee at 3 years. Panel A shows freedom from death from any cause or hospitalization for heart failure (second coprimary end point), Panel B survival, and Panel C freedom from hospitalization for heart failure.














