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Joined November 2020
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New paper from our team in Biological Psychiatry!
Can opioid withdrawal be reduced by targeting an orphan GPCR?
We identify habenular MOR neurons as drivers of naloxone aversion and show that targeting GPR139 alleviates withdrawal symptoms.
biologicalpsychiatryjournal.…
We used chemogenetics, neuronal activity, pharmacology, and spatial transcriptomics
Congrats to @DersuOzdemir, @cladomania and thanks to @GillesLaverny , @EhrlichAliza , Chunyang Jin, Marco Diana, all co-authors, and @AgenceRecherche , @Inserm, @CRBS_Strasbourg, @PICSTRA_CRBS
Emmanuel Darcq retweeted
My lab is hiring a Research Assistant @IBG_CUBoulder @CUPsychandNeuro ! This is a great opportunity to gain experience with cutting-edge systems neuroscience techniques in a collaborative research environment. Check more details below:
jobs.colorado.edu/jobs/JobDe…
Après une tentative de reconversion… clairement peu concluante 😉🍺
Retour à la science avec notre équipe addiction à Strasbourg.
Soutenez nos recherches sur le trouble de l’usage des opioïdes :
fondation.unistra.fr/projet/…
Dons déductibles des impôts 🙏
After a (clearly unsuccessful) career change attempt… 😉🍺
Back to science with our addiction research team in Strasbourg.
Support our work on opioid use disorder:
fondation.unistra.fr/projet/…
Donations are tax-deductible 🙏
Emmanuel Darcq retweeted
🚨 New review out! We summarize how MOR and NOPR exert divergent , cell-type-specific control over VTA-NAc-PFC circuits in opioid use disorder frontiersin.org/articles/10.…
Emmanuel Darcq retweeted
Proud of my team and deeply grateful for all the hard work that made this study possible.
Online now: Dual-engram architecture within a single striatal cell type distinctly controls alcohol relapse and extinction dlvr.it/TS2Fkt
Still time to apply — don’t miss the deadline (April 24)!
We are recruiting a postdoctoral fellow through the MSCA fellowship in the Addiction Research Team in Strasbourg 🇫🇷.
Join us to work on cutting-edge neuroscience and addiction research.
Addictions Team in Strasbourg, France is seeking motivated candidates to apply for a Marie Skłodowska-Curie Postdoctoral Fellowship (MSCA-PF 2026). The project will be hosted by @EDarcq @LaurenceLalanne and @Victor_Mathis_ at @Inserm
euraxess.ec.europa.eu/jobs/h…
Before April 24 2026
Thank you @Nature for highlighting our News and Views regarding the recent work from @MichaelMichaelides and colleagues : nature.com/articles/s41586-0…
Modified nitazenes, opioids 1,000 times stronger than morphine, show remarkably few adverse effects in rodents, renewing the potential of these drugs for pain relief
go.nature.com/4t4SHsp
Emmanuel Darcq retweeted
Modified nitazenes, opioids 1,000 times stronger than morphine, show remarkably few adverse effects in rodents, renewing the potential of these drugs for pain relief
go.nature.com/4t4SHsp
It was a pleasure to host the first Addiction Days in Strasbourg, centered on the theme: “Substance Use Disorders: Sources of Inter-Individual Variability & Innovative Therapies.”
The event brought together outstanding speakers and a rich diversity of perspectives.
Un podcast sur nos travaux sur nos recherches sur l’addiction aux opioïdes:
rcf.fr/culture/eureka-rcf-al…
A podcast in French about our work, tune in if you’re in the mood for some beautiful French and a great voice!
Merci @Inserm, Simon Tenaud pour ce magnifique poddcast !
Emmanuel Darcq retweeted
Nature research paper: Dopaminergic mechanisms of dynamical social specialization
go.nature.com/3NS7cAm
Huge congrats to Michael Michaelides and collaborators!
Modified nitazenes, show limited adverse effects in rodents, reopening discussions around their potential as analgesics:
lnkd.in/eSBkD4UT
With @Victor_Mathis_ , we write a News & Views: rdcu.be/fbcq1
@Nature
Emmanuel Darcq retweeted
Our team at WashU Anesthesiology is hiring a post-bac Research Technician to help us understand cognitive changes in chronic pain. Former post-bacs have all earned authorship and gone on to grad or medical school. Please pass this on to your networks!
tinyurl.com/ytaxs5wa
Please register to the Substance Use Disorders:
Sources of Inter-individual Variability & Innovative Therapies Seminars
April 1st and 2nd at Strasbourg, France
It will bring together world-leading experts in addiction
It is free (place limited): docs.google.com/forms/d/e/1F…
Emmanuel Darcq retweeted
Please share! 🚨My lab is hiring a Research Assistant! This is a great opportunity to gain experience with cutting-edge systems neuroscience techniques in a collaborative research environment. If you're interested, check the link for further details: jobs.colorado.edu/jobs/JobDe…
Addictions Team in Strasbourg, France is seeking motivated candidates to apply for a Marie Skłodowska-Curie Postdoctoral Fellowship (MSCA-PF 2026). The project will be hosted by @EDarcq @LaurenceLalanne and @Victor_Mathis_ at @Inserm
euraxess.ec.europa.eu/jobs/h…
Before April 24 2026
Emmanuel Darcq retweeted
After rising for decades in the U.S., opioid overdose deaths have been declining dramatically since 2023, with the annual rate of fentanyl overdose deaths dropping by more than a third by the end of 2024. What’s behind this sudden decline?
In this #SciencePolicyArticle, researchers evaluate the evidence for an international supply shock in fentanyl in 2023 and conclude that it could be responsible for the steep decline in overdose deaths. scim.ag/3LBm70w
Emmanuel Darcq retweeted
"C'est inenvisageable qu'on arrête !", s'alarme Gauthier Waeckerle de l'asso @IthaqueA qui gère la Halte Soin Addiction strasbourgeoise. Puis, il ajoute : "rien que pour les personnes qui viennent nous voir au quotidien, et celles que l'on héberge.
francebleu.fr/infos/societe/…
