@DrugComb

A FAIR web portal for standardization, prediction and annotation of drug combination screening data (https://xitter.cf/t.co/CpV3t3FJsi)

 Helsinki, Finland
drugcomb.org
Joined June 2019
  • Tweets33
  • Following273
  • Followers99
4Media
DrugComb retweeted
TangLab@NetPharMed3 Sep 2021
How to improve the reproducibility of drug sensitivity screens? Make your data FAIR! Check our community-driven efforts here: academic.oup.com/bib/advance… @EatrisEric @FIMM_UH @ncats_nih_gov @UCPH_BRIC @WennerbergLab @EoscLife @IMTM_Olomouc @EuOpenscreen @MarioNegriIRCCS
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Can deep-learning improve the encoding of molecular structure of a drug to understand their interactions? Check on our comparative study! Congratulations on @b_zagidullin @epitkane @gyuanfan
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Great resources for drug sensitivity data!
DrugComb@DrugComb2 Jun 2021
DrugComb update is out! Check more details at academic.oup.com/nar/advance…
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DrugComb update is out! Check more details at academic.oup.com/nar/advance…
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I am speaking at MCBIOS and MAQC Joint 2021 Virtual Conference. Please checkout the details of my talk at: whova.com/xems/apis/opengrap…
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DrugComb update paper is out! Much more drug sensitivity data resources and web applications are made available! biorxiv.org/cgi/content/shor…
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Congrats to the team! This was fun and educational.
TangLab@NetPharMed25 Mar 2021
Thrilled to be a winner of the antiPD1 response prediction @DR_E_A_M challenge! synapse.org/#!Synapse:syn184… Great to have @emmyverschuren and your group on board! @HelsinkiUniMed @FIMM_UH @helsinkiuni @iCAN_Finland
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DrugComb retweeted
TangLab@NetPharMed8 Jan 2021
I am happy to be the guest editor for the special issue of 'Network Pharmacology Modelling for Drug Discovery' in the journal of Processes. Hope to receive more insights from you! mdpi.com/si/71499
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SynergyFinder is updated! Please go to synergyfinder.org to find more! @DrugComb @NetPharMed @DrugTargetCommons
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DrugComb retweeted
TangLab@NetPharMed2 Oct 2020
Enlightening cancer drug discovery with challenge-winning AI solutions | University of Helsinki helsinki.fi/en/news/health-n… @DR_E_A_M @iCAN_Finland @FIMM_UH
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Very happy that our work on the modeling of the concepts in traditional medicine with multipartite networks is out (frontiersin.org/article/10.3… ) @NetPharMed @DrugComb @FrontiersIn @FrontPharmacol
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We are looking for a talented post-doc to leverage the huge amount of drug combination/drug target interaction data to model the drug-target-disease networks! Apply by 30.9 via bit.ly/3j2eKvM
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Very happy that our work on the ratio of coherency between the expression level and the causal relationships among the gene pairs is out(mdpi.com/2218-273X/10/6/850)#mdpibiomolecules "Can We Assume the Gene Expression Profile as a Proxy for Signaling Network Activity?" @Biomol_MDPI
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RNA Atlas of Human Bacterial Pathogens Uncovers Stress Dynamics Linked to Infection biorxiv.org/cgi/content/shor… #biorxiv_micrbio
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Packages used by DrugComb analysis service are updated under R (3.6.0) to: - TidyComb github.com/DrugComb/TidyComb (version 0.0.5) - SynergyFinder bioconductor.org/packages/re… (version 2.0.3)
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New single drug screen data from beatAML is uploaded to DrugComb. There are 528 cell lines (new primary cultured AML cells), 123 molecules (4 new molecule), and 47650 single drug dose response blocks.
DrugComb API is available right now. More details can be found in the following link: drugcomb.fimm.fi/api/
Single drug data is added to DrugComb comes from PharmacoDB dataset v1.1.1. It contains single drug dose-response experiments from 7 original datasets: UHNBreast, gCSI, CCLE, FIMM, GRAY, GDSC1000, CTRPv2. There are totally 650894 single drug-cell experiments.
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DrugComb youtu.be/Vkc8r2vV0vk via @YouTube #DrugComb #Drug_combination_data_portal

DrugComb

DrugComb is an open-access, community-driven data portal where the ...

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DrugComb data is further quality controlled. Plates with extremely values (e.g. cell viability over than 200% or less than -200%) were not displayed in the web interface (n = 226). These extreme values were usually indicative of malfunction of positive or negative controls.
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