🚨 New ACR Guidelines just released for Axisl Spondyloarthritis
New! Axial SpA Guideline Summary Just Released
A new ACR clinical practice guideline summary is now available and provides evidence-based and expert guidance for the diagnosis and management of axial spondyloarthritis (axSpA) and associated extra-musculoskeletal manifestations (EMMs) in adults and children and adolescents.
MORE → acr.tw/4eEcNUd
Thank you to @carrainc for supporting the launch of PREIM!
If you are in #pedsrheum, are a fellow or EI, and have an interest in research, this FREE meeting is for you!
Hope to see you there! #PREIM26
🎉We’re excited to launch the first Pediatric Rheumatology Early Investigator Meeting (PREIM) at PRSYM! It is open to fellows and early-career investigators in #pedsrheum, and it's free to attend!💙 Big thanks to @DrTinyTree! 🙌
Register by Feb. 15 ➡️ carra.tfaforms.net/75
Erin Tree, DO retweeted
Scenes from #ACR25. Pediatric Rheumatology Kahoot!—2nd year in a row & some friendly competition. Hosted by Pui Lee, MD, PhD, & Susan Shenoi, MD, MS. #pedsrheum
Erin Tree, DO retweeted
Great session this morning on hard-to-treat cases of juvenile localized scleroderma. I’m always glad to see my favorite pediatric rheumatologist Dr. Suzanne Li sharing her expertise to help others! #ACR25 #ACRAmbassador
Puppies at #ACR25!! They are in the exhibit hall until 4 PM.
#ACRambassador
Dr. Bas Vastert, Care Transformation in Childhood Arthritis via Precision Medicine: Window of opportunity
⭐️in non-systemic #JIA: ⬆️ inactive disease with earlier biologic start (<6mo)
⭐️in sJIA: integrating biomarkers in clinical care, early targeted tx
#ACR25 #ACRambassador
Dr. Bas Vastert, Care Transformation in Childhood Arthritis via Precision Medicine: sJIA treatment
⭐️cytokine monitoring, especially IL-18
⭐️T2T with biologic first approach in Netherlands- most patients don’t receive any GCs
#ACR25 #ACRambassador
Dr. Rae Yeung, Understanding and Harnessing the Biology of Arthritis
1. JIA classification has been a journey. Not every patient finds a home, & peds doesn’t consistently translate to adult classification. Is there a way to do this from a biologic basis?
#ACR25 #ACRambassador
Dr. Rae Yeung, Understanding and Harnessing the Biology of Arthritis
3. UCAN Biologic Classification: lots of patients and large amount of data yielded 5 clusters with clinical and biologic characteristics and distinct patterns of joint involvement
#ACR25 #ACRambassador
Dr. Rae Yeung, Understanding and Harnessing the Biology of Arthritis
4. Naming is important because guides therapy
#ACR25 #ACRambassador #kidsgetarthritistoo
Looking forward to starting my day off in the Networking Lounges for the AMIGO event at 8:20 AM. Hope to see many fellow #pedsrheum there!
#ACR25 #ACRambassador
Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Guidelines
-EULAR/PReS Still’s Guidelines
-French protocol for treatment of #JIA
-ACR Guidance for Mental Health
#ACRambassador
Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Understanding Disease
-ANA positive ITP patients have higher rates of SLE and Sjogren
-Specific inborn errors of immunity are at increased risk of ANCA and AAV features
#ACRambassador
Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Social Media
🚨 opportunity for increased healthcare provider engagement
#ACRambassador
Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Deprescribing
-a large number of patients JIA flare off therapy
-lower uveitis recurrence with slower ADA tapering schedule
#ACRambassador
Dr. Karen Onel presents #ACR25 #pedsrheum Clinical Year in Review: Medications
-New FDA approvals: emapalumab, guselkumab
-CAR-T cells in #JDM: a child with aggressive JDM achieved remission
-Stem cell transplant: high morbidity, those who survive do well
#ACRambassador
#ACR25 #pedsrheum Basic & Translational Year in Review: JIA
pubmed.ncbi.nlm.nih.gov/4060…
-Synovial tissue 🚫 peripheral blood and synovial fluid
pubmed.ncbi.nlm.nih.gov/4009…
-B cells in JIA sunovial fluid and mostly switched memory B cells, especially girls
-Autoantibodies are abundant
#ACR25 #pedsrheum Basic & Translational Year in Review: JDM
insight.jci.org/articles/vie…
and
pubmed.ncbi.nlm.nih.gov/4078…
-high IFN score, low mitochondrial score in skin
pubmed.ncbi.nlm.nih.gov/4078…
-identified pathways associated with MSA subtypes that reflect JDM phenotypes
#ACR25 #pedsrheum Basic & Translational Year in Review by Dr. Peter Nigrovic: SLE






























