Clinical Associate Professor at Imperial College London & Consultant HPB Surgeon.
London, England
Joined September 2012
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Mikael Sodergren retweeted
🔴Online: Artificial intelligence and radiologists in #pancreaticcancer detection using standard of care CT scans (PANORAMA): an international, paired, non-inferiority, confirmatory, observational study
thelancet.com/journals/lanon…
This sounds like a big deal 😳
An exciting milestone for AI in science: Our C2S-Scale 27B foundation model, built with @Yale and based on Gemma, generated a novel hypothesis about cancer cellular behavior, which scientists experimentally validated in living cells.
With more preclinical and clinical tests, this discovery may reveal a promising new pathway for developing therapies to fight cancer.
Mikael Sodergren retweeted
NEW STUDY: Mild intermittent fasting (70% diet every other day 🐁) enhances metabolic efficiency & muscle fibers but severe IF (30% diet EOD) negatively impacts glucose tolerance, trigs, liver health & does not improve muscle fibers. How fasting is done matters 💪
🙏Nice to see that this paper has proved popular online - more research is certainly needed to provide further treatment options for patients with ADHD
Link to full paper 👉onlinelibrary.wiley.com/doi/…
@ImperialMCRG @ImperialSandC @ImperialMed
Mikael Sodergren retweeted
NEW STUDY: Intermittent fasting (IF) significantly alters the microbiome of mice, with reductions in the gut production of obeticholic acid, a bile acid that induces expression of gut-derived hormones, and an increase in N-acetylglycine production
Why is this interesting? 🧵
Mikael Sodergren retweeted
Cool if true: Intermittent fasting BEFORE conception in rats apparently causes offspring to have accelerated development, including faster whisker growth, reflexes, ear unfolding & tooth eruption
So, does a mother's diet impact her eggs & therefore her babies' future? 🧵
Mikael Sodergren retweeted
Many guidelines recommend opioids for treating cancer pain
🏥🩺Here we review outcomes of Medical Cannabis therapy in 168 pts focusing on the relief of pain, quality of life and side-effects
👉shorturl.at/nFq4R
This is 💯% the future
Our new piece in @TheLancet on the potential of AI agents in medicine @james_y_zou
thelancet.com/journals/lance…
Mikael Sodergren retweeted
Fasting can expand your lifespan.
But if you do it wrong, it leads to hormonal imbalance, insomnia, and metabolism problems.
Here’s everything you need to know (& how to avoid the toxic effects): 🧵
This is a very interesting discovery! 🧬🧪🧠
The bidirectional transfer of mitochondria between cancer and immune cells is a newly discovered mechanism that thwarts anticancer defences
go.nature.com/3WyCUnb
Received an email this morning notifying me that it is 15 years today since I finished my PhD @imperialcollege! 🥳
Time sure does fly and I'm looking forward to what the next 15 years will bring...
#OurImperial
@ImperialMed @ImperialSandC @ImperialMCRG
Mikael Sodergren retweeted
How wearable sensors (@Oura, @fitbit, or @Apple watch) detected subclinical inflammation up to 7 weeks before a flare of inflammatory bowel disease
gastrojournal.org/article/S0… @RobertHirten @HPI_MS @MountSinaiNYC
Mikael Sodergren retweeted
💥First publication of 2025💥
👉An updated analysis of clinical outcomes of cannabis-based medicinal products for Inflammatory Bowel Disease in 116 pts
📈interesting association with treatment outcome and pre-morbid anxiety
tandfonline.com/doi/full/10.…
Mikael Sodergren retweeted
Ketogenic diets can prevent the increase in hunger otherwise seen with diet-induced weight loss but is severe carbohydrate restriction necessary for appetite suppression?
onlinelibrary.wiley.com/doi/…
Mikael Sodergren retweeted
1/ I've published an extended version of my FT essay: "How can Europe build its first trillion dollar start-up?" on my blog.
Here's what's in the uncut version:
Mikael Sodergren retweeted
Calorie restriction can extend a mouse’s lifespan but seems to make them less resilient @PLOSONE
journals.plos.org/plosone/ar…
