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From @JAADJournals: The exposure-adjusted adverse event rates were greatest in White children with #AtopicDermatitis treated with #cyclosporine, followed by #dupilumab & #methotrexate, with lower rates that followed a similar trend in non-White children.
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Approximately one-third of patients with interstitial granulomatous #dermatitis had a drug-induced etiology, with drug withdrawal prompting clinical improvement in nearly all of these patients.
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Over 52 weeks, nearly half (48.6%) of patients with #pemphigus treated with #rituximab combined with glucocorticoids achieved complete remission on minimal therapy, and 12.7% experienced disease relapse, researchers concluded in @JAADjournals.
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Among patients in psychiatric inpatient settings, the most common dermatologic conditions were dermatophytosis, tinea unguium, xerosis cutis, and #dermatitis and #eczema.
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Patients with #BodyDysmorphicDisorder are more likely to consult a dermatologist than a mental health specialist due to the disorder's obsessive-compulsive focus on appearance, underscoring the need for dermatologists to recognize & address the condition.
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Apremilast was associated with significantly greater improvements than placebo across multiple efficacy measures in patients with plaque #psoriasis with limited skin involvement, including those with scalp, genital, and/or nail psoriasis.
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The risk for primary biologic failure in the treatment of #psoriasis was greatest with tumor necrosis factor-α inhibitors compared with interleukin-17 and interleukin-23 pathway inhibitors.
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Dermatology Advisor spoke with Abigail Waldman, MD (@abbywaldman), a dermatologist and Mohs surgeon who frequently uses her TikTok platform as an avenue for patient education and connection.
Listen to the interview: dermatologyadvisor.com/podca…
Pediatric-onset #psoriasis was associated with greater improvements in clinical outcomes than adult-onset psoriasis among those who received interleukin-17 inhibitors, but the same association was not observed for other systemic therapies.
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Improvements in both investigator- and patient-reported outcomes were observed at 12 months of treatment with #tralokinumab for #AtopicDermatitis, with no new safety signals identified.
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The ability of ketamine to modulate central sensitization suggests a larger role for the drug in the management of chronic neuropathic pain beyond analgesia.
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Although coexisting chronic pelvic pain and fibromyalgia diagnoses are common, frequency varies based on phenotype and disease setting.
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Prior visits to the emergency department among patients with chronic spontaneous #urticaria was independently associated with concomitant angioedema and inversely associated with the presence of an identifiable trigger.
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Significant improvements in actinic keratosis severity were seen as early as 3 months of treatment among patients who received oral #retinol supplementation with medical photoprotection.
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Brepocitinib in patients with #dermatomyositis was associated with improvements in cutaneous disease activity, #pruritus, and skin-related quality of life through 52 weeks, investigators concluded in @JAMADerm.
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Among patients with skin symptoms in cutaneous #lupus erythematosus or systemic lupus erythematosus, most patients who received enpatoran 25 mg, 50 mg, or 100 mg achieved a 50% or 70% improvement in disease activity at week 24. #EADV2026
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At least 1 nail disorder was reported by 66.3% of patients who used glucagon-like peptide-1 receptor agonists compared with 52.8% of control patients, according to study results presented at the #EADV2026.
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Larger weight gains were observed in girls aged 2 to less than 6 years who were below the 25th percentile for weight & received #dupilumab (45.2%) compared with girls who received placebo (10.0%) and matched boys (13.9% vs 6.5%, respectively). #EADV2026
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Cherry angiomas occurred more frequently in patients with #neurofibromatosis type 1 compared with control patients at rates of 48% vs 18%, researchers concluded in @JAMADerm.
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Women with androgenetic #alopecia who received spironolactone had greater improvement in Sinclair grades from baseline to month 24 than those treated with bicalutamide.
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