Cardiovascular Physiology Postdoc at @UTSWMedCenter Division of Vascular Medicine | Focused on arterial hemodynamics | Views are my own.
Dallas, TX
Joined February 2016
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- Following2.3K
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Denis Wakeham retweeted
Research Article by BN Balmain et al. (@denwakeham @mick_leahy) #Oxygen cost of breathing and its association with #dyspnea in older patients with #heartfailure with preserved #ejectionfraction and #obesity
ow.ly/uucO50ZB5Bj
Denis Wakeham retweeted
Elevated V-waves are associated with pulmonary vascular remodeling in patients with heart failure with preserved ejection fraction @BrazileTiffany @DenWakeham @mick_leahy_ ahajrnls.org/4dZ81BN
Denis Wakeham retweeted
Happy to share our work on epicardial adipose tissue and exercise hemodynamics in HFpEF in @JCFINT 🚀
We used cMRI ➕ invasive hemodynamics ➕ upright exercise to understand the effect of EAT in patients with obesity and HFpEF
doi.org/10.1016/j.yjcafi.202…
@DenWakeham @BrazileTiffany
Very happy to share that I just received the Notice of Award for my NIH K99/R00 that will perform high-resolution phenotyping of the hemodynamic consequences of thoracic aortic aneurysms and their repair.
Look forward to improving patient outcomes for those with aortic disease!
Denis Wakeham retweeted
Our latest cover image comes from this article from @DenWakeham (@UTSWMedCenter) et al., as they set out to determine if it is possible to assess #aortic stiffness from standard #cardiac MRI.
📜 buff.ly/fvmdU4S
Denis Wakeham retweeted
New by @GManferdelli and colleagues in HAMB
Ignoble Gas: The Questionable Role of Xenon in Rapid Ascents of Mount Everest
liebertpub.com/doi/10.1177/1…
Denis Wakeham retweeted
Collected some our of thoughts regarding heart-lung interactions during exercise in patients with HFpEF in Heart Failure Reviews.
Really, a lot of unknowns in both healthy and clinical populations.
Bonus points if you catch the lyrics ;)
link.springer.com/article/10…
Denis Wakeham retweeted
Earlier this year, Xenon was described by media as the missing piece to climb Everest faster and safer......Scientific evidence suggests it is not❌
Ignoble Gas: The Questionable Role of Xenon in Rapid Ascents of Mount Everest
liebertpub.com/doi/abs/10.11…
Denis Wakeham retweeted
Mini-Review by @N_A_Carlini et al. (@UVRLphysiology @K_Bunsawat @UUtah @CUAnschutz @uiowa) #Vascularfunction in women with #heartfailure with preserved #ejectionfraction: a mismatch beyond #diastole
ow.ly/bPQU50WTu5Z
Really happy to see this published in EJHF. Joey, Chris and I show that middle-aged adults with severe obesity present with absolute hypervolemia, relative hypovolemia and disproportionate LV enlargement. @utswheart @UTSWMedCenter @texashealth @IEEMPHD
doi.org/10.1002/ejhf.70037 – at Dallas, TX
Great work from @AlexSullivan_MD, @JoshuaBeckmanMD & others. Really glad to be involved with this great team and important work. Much more to come from @JoshuaBeckmanMD, myself and our colleagues in the @UTSWMedCenter Division of Vascular Medicine. – at Dallas, TX
Ever wonder why walking capacity varies across ABIs in patients with PAD?
Calf skeletal muscle microvascular dysfunction, not conduit artery occlusive disease, is the strongest driver of walking impairment in PAD.
Happy to share our work in @CircIntv.
ahajournals.org/doi/10.1161/…
Denis Wakeham retweeted
🚨Funded PhD opportunity @LboroSSEHS - starting October 2025!
🔓Exploring iron status and supplementation in athletic individuals.
✨Supervisory team: myself, @LJJ_nutrition and Lettie Bishop.
🔗 lboro.ac.uk/study/postgradua…
Denis Wakeham retweeted
Research Article by @ZachMcKenna_PhD et al. (@whitleyatkins) Evaluating low-energy cooling strategies on #thermal and #cardiacstrain in older adults exposed to very hot and dry heat with accompanying activities of daily living
ow.ly/NV2r50WsP77
Denis Wakeham retweeted
What is the contribution of abnormal lung mechanics to the rise in ventricular filling pressures in HFpEF during exercise ?
Elegant work by the IEEM @UTSWMedCenter on the study of hemodynamics, lung mechanics and HFpEF now in @JACCJournals #JACCHF
📎 jacc.org/doi/10.1016/j.jchf.…
Really happy to see our paper published in @JHypertension. @Deoliveiragdc and I show that the BP pressure response to exercise is not different between hypertensive adults with LVH and healthy controls when normalized for VO2.
journals.lww.com/jhypertensi… – at Dallas, TX
Denis Wakeham retweeted
Julian C. Bommarito & Philip J. Millar (@UofG_HHNS) offer this #Perspective 'Metabolic override: Adding neuropeptide Y to the list of vasoconstrictors attenuated by exercise' based on the work of Wakeham et al. (2025) 💭
🔗 buff.ly/f7UxgmD
Denis Wakeham retweeted
New in @japplphysiol by @ZachMcKenna_PhD and colleagues
Evaluating low energy cooling strategies on thermal and cardiac strain in older adults exposed to very hot-dry heat with accompanying activities of daily living
journals.physiology.org/doi/…
Denis Wakeham retweeted
In this recent study, Denis J. Wakeham (@UTSWMedCenter) et al. investigated functional sympatholysis of neuropeptide Y-mediated #vasoconstriction in humans 🫀🏃
📜 Read the #Research here: buff.ly/VYNVPm9
Happy to share our recent paper published in @JPhysiol that shows, for the first time in humans, that Neuropeptide Y mediated vasoconstriction is sensitive to functional sympatholysis, to a similar degree that is alpha-adrenergic vasoconstriction.
physoc.onlinelibrary.wiley.c…
First of many papers in this area from Chris M. Hearon Jr.'s lab at @IEEMPHD (@texashealth) and @UTSWMedCenter. Thanks to our collaborators, Paul Fadel and Scott Davis, on this project. – at Dallas, TX
