@DelcoLab

Mitochondrial (dys)function in orthopedic soft tissues | Regenerative orthobiologics | Translational animal models | Cornell Veterinary Medicine | One Health

 Ithaca, NY
Joined October 2019
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  • Followers128
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Read about Dr. Hargitaiova’s path from equine clinical practice to academic research - where mitochondria meet orthopedics in the race to heal from within. 🐎🧬 🔗 ors.org/kristyna-hargitaiova… @kristyhargitai #ORS #WomenInSTEM #Mitochondria
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Just back from the first ever Mitochondrial Transplantation & Next Gen Therapeutics Conference at @HofstraU , where Drs. Delco and Hargitaiova were awarded the Mitochondrial Rising Star award and enjoyed Dr. Szeto's insightful talk! 🧬⚡🐎
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Wrapped up an incredible week at @roodandriddle! Now back to research, prepping for my Tuesday conference talk at @HofstraU - and yes, had to try Kentucky bourbon in the cutest horsie thermos! 🐎🥃
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Less than 2 weeks until Delco Lab presents our work on mitochondria-targeted therapies at the Mitochondrial Transplantation & Next Gen Therapeutics meeting at @HofstraU ! Catch talks by Dr. Delco, Dr. Hargitaiova & our amazing collaborator Dr. Hazel Szeto on April 29! 💊🔥
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📙 This study by @DelcoLab (@cornellvet) reveals how mesenchymal stem cells transfer mitochondria to chondrocytes, a key mechanism of MSC therapeutic activity. Oxidative stress boosts this transfer, with the Cx43 isoform GJA1-20k playing a major role. ➡️stemcellres.biomedcentral.co…
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🔙 Flashback to #ORS2025! Dr. Michelle Delco, Dr. Kristyna Hargitaiova & Dr. Lindsay Seewald presented their exciting cartilage research. Congratulations to Dr. Hargitaiova who won the 3R Preclinical Models Award! 🏆 Thanks to our collaborators @BonassarLab & @HSpecialSurgery!
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Future scientists in action! Undergraduates Gianna Leon mastering cartilage histology staining techniques and Claire Ma feeding her cells. #LabLife #WomenInSTEM #SheInnovates
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Dr. Delco and Dr. Hargitaiova teaching joint dissection techniques to future biomedical engineers experts @BonassarLab @CornellBME
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Our newest exciting study of mitochondrial transfer between MSCs and chondrocytes has been published! pubmed.ncbi.nlm.nih.gov/3939…

Connexin 43 regulates intercellular mitochondrial transfer from human mesenchymal stromal cells to...

Overexpression of GJA1-20k in MSCs increases mitochondrial transfer to chondrocytes, highlighting GJA1-20k as a potential target for promoting mitochondrial transfer from MSCs as a regenerative...

pubmed.ncbi.nlm.nih.gov
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A new collaborative study on MRSA-infected equine wounds treated with MSCs has been published! pubmed.ncbi.nlm.nih.gov/3936…

Preliminary in vivo investigation of the mesenchymal stromal cell secretome as a novel treatment...

This pilot study contributes to a growing understanding of the equine MSC secretome as an antimicrobial and pro-healing therapeutic for equine wounds.

pubmed.ncbi.nlm.nih.gov
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Flashback to the 2024 International Gap Junction Conference in Arlington! Drs. Delco and Hargitaiova presented our research on Cx43 Mediating Mitochondrial Transfer from MSCs to Chondrocytes and Cx43 role in Early Post-Traumatic OA Progression.
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@DelcoLab is excited to announce an interdisciplinary #postdoc position with @BonassarLab and @LASSP_Cornell! Reach out via DM or email for more info. #orthoresearch
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Proud to have my 3rd #scicomm article for @CornellRsrch feature the work of a dedicated and diversity-promoting graduate student who studies apple genetics! research.cornell.edu/news-fe…
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Congrats to Caroline Thompson (linkedin.com/in/carolinebike…) on her NYSTEM-funded Stem Cell Program training fellowship! She will be collaborating with @DelcoLab to enhance mitochondrial transfer from MSCs for arthritis therapy. #SupportNYSTEM @CornellBME #osteoarthritis #mitochondria
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Very proud of @Becka_Irwin_ for participating in @GordonConf #cartilageGRC and bringing home a poster session award! We’re quite jealous of her views from the conference center. #GRC
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A cell videoed through a microscope. DNA (cyan), mitochondria (yellow), and VASP (magenta) are shown. #CellBiology
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A research study led by #CornellVet's Dr. Michelle Delco (@DelcoLab) may offer a new explanation of how stem cells can prevent cartilage loss and chronic pain after joint injury, which could pave the way for new arthritis treatments in animals and humans.vet.cornell.edu/news/2023021…

Helping cartilage heal itself

An interdisciplinary team of Cornell researchers led by Dr. Michelle Delco D.V.M. ’02, PhD ’16 has made a series of discoveries that offer a new explanation of how stem cells can prevent cartilage...

vet.cornell.edu
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We are Dallas bound! The Bonassar Lab is thrilled to share our work at #ORS2023. Check out the presentations below to learn more about the ongoing work in our lab 😊🔬 @ORSsociety @ORSSpineSection @ORSMeniscus @CornellBME
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Make sure to meet our talented post-doc @Becka_Irwin_ and veterinary research student Kaylee Montney at @ORSsociety 2023 annual meeting:
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Please go check out our @ORSsociety posters Fri-Tues that highlight excellent OA & tendon collaborations from our lab @SchnabelLab (poster 2070) and the @mattbfish lab (poster 1248). Hope everyone enjoys the annual meeting! #ORS2023
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