@DekaneyLab

Intestinal Damage and Repair Lab at NC State University, College of Veterinary Medicine

 Raleigh, NC
Joined August 2017
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  • Following39
  • Followers60
11Media
👏👏👏 The @NCStateAlumni Association has given two #NCStateVetMed professors prestigious awards for 2023. Dr. Duncan Lascelles received the Distinguished Graduate Professor Award. Dr. Anthony Blikslager received the Outstanding Research Award. DETAILS: ncst.at/Ty5V50NIAFQ
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Recruiting a fabulous lab manager! Position is shared between two research labs at NC State College of Veterinary Medicine! See posting for details jobs.ncsu.edu/postings/15885…
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Researchers from our Molecular Biomedical Sciences & Population Health & Pathobiology departments plus @Duke_PCB recently published, "Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal stem cells"@tandfonline doi.org/10.1080/19490976.202…

Prolonged oral antimicrobial administration prevents doxorubicin-induced loss of active intestinal...

Acute intestinal mucositis is a common off-target effect of chemotherapy, leading to co-morbidities such as vomiting, diarrhea, sepsis, and death. We previously demonstrated that the presence of en...

tandfonline.com
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Congrats @PackFootball on the win over UNC!
Happy Thanksgiving!
Check out this interesting review by our graduate student @sarajerwin, hot off the presses. Nice work, Sara! #vetscience #colic #gutbrain 👉🏼tinyurl.com/foalcolic 👈🏼
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Amazing paper from some close colleagues of mine! Congrats on getting this out after years of hard work! 🙌 #gastroenterology #basicscience #enteroids journals.physiology.org/doi/…
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Paneth cells can influence the stem cell niche, other cells, and other organ systems in both homeostasis and damage @DekaneyLab ow.ly/EtHE50GzwZX
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Interested in microRNAs and the intestinal epithelium? Check out our recent pub in @ajpgi: doi.org/10.1152/ajpgi.00222.…! Shout out to project leads Mike Shanahan and @KankeMatt @cornellvet and co-authors @eliataitwojno @jakob_moltke @DekaneyLab @K_hyphen_L @AmyHung_yh and others!

Multiomic analysis defines the first microRNA atlas across all small intestinal epithelial lineages...

MicroRNA-mediated regulation is critical for the proper development and function of the small intestinal (SI) epithelium. However, it is not known which microRNAs are expressed in each of the cell...

journals.physiology.org
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Dekaney Lab retweeted
AAEP@AAEPHorseDocs30 Sep 2021
As the AAEP honors #NationalHispanicHeritageMonth, we spotlight research trailblazer & AAEP volunteer Dr. Liara Gonzalez. She is an associate professor of gastroenterology & equine surgery at @NCStateVetMed, where she also leads the Intestinal Regenerative Medicine Research Lab.
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Congrats @PackFootball
NC State Football
@PackFootball25 Sep 2021
FINAL SCORE! WOLFPACK WINS! #HTT
Check out the newest paper from the Nascone-Yoder lab: "Single-minded 2 is required for left-right asymmetric stomach morphogenesis", a super cool story now out in @Dev_journal!! journals.biologists.com/dev/…

Single-minded 2 is required for left-right asymmetric stomach morphogenesis

Summary:Single-minded 2, homolog of a gene required for gut looping in Drosophila, acts downstream of Pitx2 to regulate asymmetric stomach curvature in vertebrates.

journals.biologists.com
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Dekaney Lab retweeted
CMGH@AGA_CMGH9 Jul 2021
Early progeny cells derived from Lgr5+ cells are resistant to damage and contribute to repair @DekaneyLab ow.ly/Q04U50FmfYQ
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WE'RE HEADED BACK TO OMAHA!!!
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Congrats to @NCStateBaseball on making it to the College World Series!
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Congrats to all of our fantastic and beyond-impressive graduate program scholars graduating today. You did it!
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The study by our CVM faculty & researchers from @NCStateSciences, @DukeU and @UMich, "Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal Stem Cells" is linked below! Congrats on the collaborative work! pubmed.ncbi.nlm.nih.gov/3357…

Epithelial Regeneration After Doxorubicin Arises Primarily From Early Progeny of Active Intestinal...

We show that DXR effectively depleted aISCs in the small intestine and subsequent epithelial regeneration depended on nonquiescent early progeny cells of aISCs. The chemoresistant phenotype of the...

pubmed.ncbi.nlm.nih.gov
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Research success: How NC State Vet Med's culture of support fuels a rise in grants, innovation. ow.ly/RMjJ50DxHCZ
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A CVM study coauthored by several Molecular Biomedical Sciences faculty hypothesized that doxorubicin (DXR) treatment results in increased paracellular translocation of bacteria or bacterial products through the small intestinal epithelium. Read it here! nature.com/articles/s41598-0…

Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

Scientific Reports - Doxorubicin increases permeability of murine small intestinal epithelium and cultured T84 monolayers

nature.com
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New paper from the Dekaney Lab out today. rdcu.be/cbQ4L. Congrats Paul Cray, Jocsa Cortes and @BreannaSheahan!
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Thanks for all the support @CVMResearch!
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