@DeboraMarksLab

Debbie Marks' Lab at HMS

deboramarkslab.com
Joined July 2021
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Can generative models of viral evolution to predict viral mutants that escape from antibodies ? - see poster/ spotlight talk at ICML WCB icml-compbio.github.io/2021/…
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Fabulous - and tested - more than wishful thinking. Now - what shall we design ?
Ali Madani
@thisismadani19 Jul 2021
This twirling work of science is special ✨ AFAIK, it's the first crystal structure of a functional #protein fully designed by #AI A milestone in our quest to use language models to generate proteins that are unseen in nature & can function well in the real-world. Read below👇
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Whoops - correct links here @EliWeinstein6 icml.cc/virtual/2021/poster/… proceedings.mlr.press/v139/w…
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We want to build generative models to predict functional sequences: E.g. What future viral sequences will emerge? Check our paper at ICML 2021 led by grad student @EliWeinstein6 proceedings.mlr.press/v139/w… 1/7
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Shocking even to me - 88% AUCs from these microbiome papers can’t be trusted - data leakage ++ - time to check other ML- Bio claims arxiv.org/abs/2107.03611
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#SARS_CoV_2 is there a trade off between transmissibility and pathogenicity ?
13%Yes - worst is over
26%No chance
60%Only over long time scale
53 votes • Final results
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