Davare Lab retweeted
It is with great honor that I share our most recent publication, exploring actionability of acquired #PDGFRA fusions in #GBM. We show evidence of clonal sweep after exposure to an #EGFR monoclonal antibody and successful targeting of the newly acquired MDM2-PDGFRA fusion. This emphasizes the importance of repeat #NGS in patients with recurrent #GBM, evolution of #glioblastoma through several rounds of therapy and proactive monitoring and treatment through its evolution. Thank you to all my collaborators! @DavareLab @ChrisFebres @RandyDAmico_MD @johnboockvar @tamikawong1163 @JLG_Marti @SaeedAsiry @NaturePortfolio @Nature_NPJ @NeuroOnc nature.com/articles/s41698-0…
Most negative results remain unpublished, creating blind spots in AI training and risking suggestions of already-failed ideas. AI can transform science—but only if it sees the full record of scientific successes and failures. nature.com/articles/d41586-0…
#AI #OpenScience #scicomm
Davare Lab retweeted
“When I met Dr. Cetnar, he had an associate who was doing research with ROS1.
They told me my diagnosis, explained everything about it, and gave me so much relief and hope I said, ‘Can I hug both of you? You both gave me my life back.’"
Clare's story: bit.ly/4fVcP8J
ROS1 researchers & enthusiasts! Check our new paper: loss of ROS1's extracellular domain alone drives oncogenic activity, no N-terminal fusion partner needed. Dreaming of future cryo-EM studies... funding willing!
nature.com/articles/s41598-0…
Davare Lab retweeted
“This effort fills a critical gap in pediatric oncology and will accelerate effective treatments for youth impacted by these devastating bone cancers.”
- @KuniFoundation president Angela Hult: bit.ly/3AAHSYw
Davare Lab retweeted
PDX vs. original tumor in childhood cancer👇
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In press!
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors | EMBO Molecular Medicine embopress.org/doi/full/10.15…
#ROS1 @EmboMolMed
Davare Lab retweeted
Certain oncogene drivers have a higher affinity for brain metastases. Should our screening guidelines change? @EditorNeuro @NeuroOnc @RandyDAmico_MD #brainmetastases #NSCLC @NorthwellHealth @LenoxNeurosurg
Brain metastasis screening in the molecular age academic.oup.com/noa/article…
Davare Lab retweeted
I remember interviewing for a faculty position once, being co-first author with a man on a publication, and being asked if I really contributed equally to the work. This confirms what we women have known for a long time.
In case you missed it: Women are less likely to be credited for their scientific contributions than men. It’s true across multiple fields & at all stages, with important repercussions for career progress. #WomenInSTEM #WomenInMedicine #MedTwitter
nature.com/articles/s41586-0…
Help support the Pediatric Brain Tumor Program at OHSU Doernbecher Children's Hospital and sport a cool T-Shirt while doing it!
pbtp.webstarts.com/
#pediatric_cancer #braincancer @OHSUDoernbecher
Davare Lab retweeted
Women who never smoked have twice the risk of developing #lungcancer as men. A study in Sept 2020 in Lung Cancer Management showed that ~ half of women dx w lung cancer globally never smoked vs ~ 15-20% of men.
Ladies, pls watch out for symptoms. 💔 #lcsm
everydayhealth.com/cancer/lu… – at Kensington, London
Davare Lab retweeted
Representing @OHSUKnight at #TTLC23 in Santa Monica!
Dr Cetnar was a panelist on the mesothelioma and thymic malignancies session.
@rajatthawani presented his research from the @DavareLab
Is there more to ROS1 in cancer than the ROS1 fusions? Targetable by ROS1 TKI? Yes, maybe. See our pre-print. #ROS1
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors biorxiv.org/cgi/content/shor… #bioRxiv
Davare Lab retweeted
.@OHSUKnight is hiring a #sarcoma med onc (Asst Prof) to join our thriving and expanding team.
#OHSUsarcoma is collaborative & engaged group dedicated to sarcoma patients and research - and we're FUN!
DM me or apply here: bit.ly/3TMsMUe
Davare Lab retweeted
Congratulations to our fellow @RajatThawani for being awarded the Medical Research Foundation Early Career Investigator Grant, with mentorship from the @DavareLab. He will work on strategies to bypass intrinsic resistance in ROS1 rearranged NSCLC. @ros1cancer #LCSM
Davare Lab retweeted
Mr T continues to raise awareness for #lungcancer, but this year from heaven.
#cancer may steal from us the people (+#dogs + #cats) we love. But as Mr T’s sign says, we have to keep fighting the fight + helping each other.
Pls like + RT if you agree.
#LCAM #StrongerTogether – at Nashville, TN
Our recent collaboration with Dr. Angela Waanders @LurieChildrens, @adamcresnick, @JainPayal022 reveals actionable ROS1 alterations in rare pediatric cancer. NGS should be every cancer patients healthcare right! @molcasestud molecularcasestudies.cshlp.o…
Davare Lab retweeted
Five of the seven #lungcancer #patient advocates in this photo have died since the picture was taken 3 years ago. Please support lung #CancerResearch -- lots of options: @lcfamerica @LUNGevity @lcrf_org @GO2Foundation @IASLC @fredhutch @CUCancerCenter #LCSM



















