https://xitter.cf/t.co/TR0s9njP9W

Portland, OR
Joined December 2020
It is with great honor that I share our most recent publication, exploring actionability of acquired #PDGFRA fusions in #GBM. We show evidence of clonal sweep after exposure to an #EGFR monoclonal antibody and successful targeting of the newly acquired MDM2-PDGFRA fusion. This emphasizes the importance of repeat #NGS in patients with recurrent #GBM, evolution of #glioblastoma through several rounds of therapy and proactive monitoring and treatment through its evolution. Thank you to all my collaborators! @DavareLab @ChrisFebres @RandyDAmico_MD @johnboockvar @tamikawong1163 @JLG_Marti @SaeedAsiry @NaturePortfolio @Nature_NPJ @NeuroOnc nature.com/articles/s41698-0…
2
4
1
10
1,612
Most negative results remain unpublished, creating blind spots in AI training and risking suggestions of already-failed ideas. AI can transform science—but only if it sees the full record of scientific successes and failures. nature.com/articles/d41586-0… #AI #OpenScience #scicomm
1
1
4
380
“When I met Dr. Cetnar, he had an associate who was doing research with ROS1. They told me my diagnosis, explained everything about it, and gave me so much relief and hope I said, ‘Can I hug both of you? You both gave me my life back.’" Clare's story: bit.ly/4fVcP8J
1
2
2
383
ROS1 researchers & enthusiasts! Check our new paper: loss of ROS1's extracellular domain alone drives oncogenic activity, no N-terminal fusion partner needed. Dreaming of future cryo-EM studies... funding willing! nature.com/articles/s41598-0…
1
1
1
6
789
Loss of ROS1's extracellular domain may suffice for catalytic activation. However, the 5' fusion partner's promoter/enhancer will be required to drive its expression in diverse cancer cell lineages, as ROS1 expression is normally highly restricted in most adult human tissues.
3
87
“This effort fills a critical gap in pediatric oncology and will accelerate effective treatments for youth impacted by these devastating bone cancers.” - @KuniFoundation president Angela Hult: bit.ly/3AAHSYw
1
1
1
4
257
PDX vs. original tumor in childhood cancer👇
This Post is from an account that no longer exists. Learn more
1
474
In press! Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors | EMBO Molecular Medicine embopress.org/doi/full/10.15… #ROS1 @EmboMolMed
1
6
9
10,728
I remember interviewing for a faculty position once, being co-first author with a man on a publication, and being asked if I really contributed equally to the work. This confirms what we women have known for a long time.
In case you missed it: Women are less likely to be credited for their scientific contributions than men. It’s true across multiple fields & at all stages, with important repercussions for career progress. #WomenInSTEM #WomenInMedicine #MedTwitter nature.com/articles/s41586-0…
1
6
1
13
5,776
Help support the Pediatric Brain Tumor Program at OHSU Doernbecher Children's Hospital and sport a cool T-Shirt while doing it! pbtp.webstarts.com/ #pediatric_cancer #braincancer @OHSUDoernbecher
1
3
278
Women who never smoked have twice the risk of developing #lungcancer as men. A study in Sept 2020 in Lung Cancer Management showed that ~ half of women dx w lung cancer globally never smoked vs ~ 15-20% of men. Ladies, pls watch out for symptoms. 💔 #lcsm everydayhealth.com/cancer/lu… – at Kensington, London
4
10
503
Representing @OHSUKnight at #TTLC23 in Santa Monica! Dr Cetnar was a panelist on the mesothelioma and thymic malignancies session. @rajatthawani presented his research from the @DavareLab
1
1
15
1,288
Is there more to ROS1 in cancer than the ROS1 fusions? Targetable by ROS1 TKI? Yes, maybe. See our pre-print. #ROS1
Discovery of oncogenic ROS1 missense mutations with sensitivity to tyrosine kinase inhibitors biorxiv.org/cgi/content/shor… #bioRxiv
1
2
1
7
2,931
.@OHSUKnight is hiring a #sarcoma med onc (Asst Prof) to join our thriving and expanding team. #OHSUsarcoma is collaborative & engaged group dedicated to sarcoma patients and research - and we're FUN! DM me or apply here: bit.ly/3TMsMUe
2
10
3
33
Congratulations to our fellow @RajatThawani for being awarded the Medical Research Foundation Early Career Investigator Grant, with mentorship from the @DavareLab. He will work on strategies to bypass intrinsic resistance in ROS1 rearranged NSCLC. @ros1cancer #LCSM
1
2
15
Mr T continues to raise awareness for #lungcancer, but this year from heaven. #cancer may steal from us the people (+#dogs + #cats) we love. But as Mr T’s sign says, we have to keep fighting the fight + helping each other. Pls like + RT if you agree. #LCAM #StrongerTogether – at Nashville, TN
7
20
1
94
Our recent collaboration with Dr. Angela Waanders @LurieChildrens, @adamcresnick, @JainPayal022 reveals actionable ROS1 alterations in rare pediatric cancer. NGS should be every cancer patients healthcare right! @molcasestud molecularcasestudies.cshlp.o…
1
4
Five of the seven #lungcancer #patient advocates in this photo have died since the picture was taken 3 years ago. Please support lung #CancerResearch -- lots of options: @lcfamerica @LUNGevity @lcrf_org @GO2Foundation @IASLC @fredhutch @CUCancerCenter #LCSM
9
25
8
94