Works on health policy and strategy. Thinks about lots of other stuff. Still believes it is possible to disagree with you and like you as a person.

Toronto
Joined February 2012
Dan Carbin retweeted
Max Scherzer leaves the mound to a standing ovation for what could be the final time in his legendary career 👏
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How does Trump not realize that tariffing or banning imports fuels inflation for Americans and requires the Fed to raise rates further and faster? He doesn't even have a basic understanding of economics. cnn.com/2026/09/04/economy/t…
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Unfortunately , there seems to be a culture of complacency / defeatism in many Ministries of Health across the country. We don’t have to accept deteriorating performance. There are proven answers out there. thestar.com/opinion/contribu…
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What a horrible deal we were compelled to sign with these economic terrorists. Could we at least slap an export tax on potash to recover some of the losses?“Gordie Howe bridge deal appears to contradict Carney’s description of pact with U.S.” theglobeandmail.com/politics…
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"How much “value-added” did the CPP managers earn this year? Er, none, as it happens. Actually, they got beat by the indexes, too. Sorry, did I say beat? Correction: they got smoked. The Fund earned 7.8 per cent. That 85-15 portfolio? 13.9 per cent." theglobeandmail.com/opinion/…
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If this kind of change keeps up it will require significant changes to the regulatory and funding process for drugs in all countries. We are going to see a wave of new innovation.
It's genuinely insane how much progress biotech has made in the last 90 days: - Two years ago I watched Lucy Therapeutics shut down after 7 years and $42M from Bill Gates, never reached human trials. Last month DeSci crowdfunded €2.5M in 72 hours for Dr Barbacid cancer trials and went straight to human trials. Zero VCs and zero committees in the middle. And it's not even about the money. The goodwill - Gene therapy cost $2-4M per treatment a year ago because manufacturing was artisanal and nobody was actually solving it. Now automation's dropping costs toward $200. Turns out it was an engineering problem all along. - Just a year ago, the FDA wouldn't touch longevity. In January 2026, first FDA-approved human trial reversing cellular age launched (ER-100). We're testing age reversal in humans right now. Not mice. - Psychedelics stuck in regulatory hell for 50 years. In February 2026, Compass crushed Phase III for psilocybin in treatment-resistant depression. - In 2023, AI drug discovery was hype. $17B got invested, zero approved drugs. Early 2026, Ginkgo x OpenAI ran over 200k autonomous experiments, 36K of those were unique. Protein costs dropped by 40% and they're already shipping commercially. Discovery timelines collapsed. - Just last year, FDA required full GMP pre-Phase 2, moved at 1950s speed. This quarter,we're fast-tracking frontier therapies, relaxing requirements, launching pilots. Something shifted and the regulatory wall is cracking. - In 2024, clinical trials had to run in US at 2x cost, half the speed. Right now in Singapore and China running trials 50% cheaper, 2x faster. Companies routing around FDA entirely. The US model is optional. I could keep going on with these, but you realize that the bottleneck was never the science. It was funding models, regulatory speed, manufacturing, geography etc And most of them are breaking since last October. Biotech has shed 30 years of broken infrastructure in 5 months and I can't be more bullish. bio/acc.
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I worked for a Premier & 2 Cabinet Ministers. Having your correspondence subject to FOI is a PITA, but it is the price of serving the public in a democracy. This move is profoundly bad public policy. By making it retroactive, it reeks of cover-up. cbc.ca/news/canada/toronto/o…
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The rigidity in Canadian thinking about this kind of thing is so disappointing as a citizen & taxpayer. I would much prefer that the costs of hosting a commercial event (the World Cup) be covered by corporate sponsors as opposed to tax payers. theglobeandmail.com/canada/a…
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It was pretty clear at the time that this was a depressing lurch towards authoritarianism in Canada. It just happened to come from the left and thus didn’t align with the dominant narrative of the moment, allowing Trudeau to mostly get a way with it. theglobeandmail.com/canada/a…
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Dan Carbin retweeted
My comments on the Trump Administrations’s new “National Security Strategy” open.substack.com/pub/bobrae…
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