
π Global, multicenter RCT ischemic#stroke π¬ Investigating thrombolysis to improve mRS in people with recent DOAC intake π ClinicalTrials NCT06571149 @snf_ch
@StrokeBern @PHRIresearch
Joined November 2023
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π¨ DO-IT Trial Milestone π¨
Weβve crossed 100 patients β now 107 enrolled across Europe! π
π¨π55 | π©πͺ23 | π§πͺ14 | π³π±12 | πͺπΈ2
Huge thanks to every team, site, and patient making this happen.
π Recruit. Care. Cure. DO-IT!
πBreaking newsπWe would like to welcome the @DOIT_trial study teams in Ulm, Leipzig, Ludwigshafen, and Bad Neustadt to the @DOIT_trial community!π₯³ we are thrilled to have you on board, actively screening and recruiting patients!
π’We would like to welcome the trial teams in Brussels and Sanderbusch to the @DOIT_trial and community.
π₯³We very much look forward to have your centers active and recruiting in the coming days. We are thrilled to have you on board.π
π¨ Missed it? Catch up on the Stroke Alert Podcast featuring @TotoMynell on the DO-IT Target Trial Analysis β key insights into thrombolysis in DOAC-treated stroke patients.
Donβt miss this one! π§
Stroke Alert October 2025 strokealert.libsyn.com/strokβ¦
DO-IT Trial retweeted
The DO-IT study is gaining momentum in Europe, and Canada is next! π¨π¦ Are you ready to DO IT? ππͺπ
π Exciting DO-IT Trial Update!π
π π The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far!
- 27 inπ¨π
- 3 in the π³π±
- 2 in π§πͺ
- 1 in πͺπΈ
π A big thank you to everyone contributing!
ππ§ββοΈRecruit. Care. Cure. DO-IT!
π Exciting DO-IT Trial Update! π
π π Just this week, we received final regulatory approval for additional sites in Germany, Spain, the Netherlands and Belgium through CTIS. Thus, a total of 52 sites have already been approved!
π©πͺπͺπΈπ³π±π§πͺ
ππ§ββοΈSmall Steps. Big Impact. DO-IT!
π Exciting DO-IT Trial Update!π
π π The trial continues to expand, with 24 sites actively recruiting across Europe and 33 patients enrolled so far!
- 27 inπ¨π
- 3 in the π³π±
- 2 in π§πͺ
- 1 in πͺπΈ
π A big thank you to everyone contributing!
ππ§ββοΈRecruit. Care. Cure. DO-IT!
π¨Exciting DO-IT Trial Update!π¨
Co-funding has been granted from PHRC-N for France. A big thank you to Guillaume Turc and their teams for this great accomplishment.
π Exciting DO-IT Trial Update!π
π π The trial continues to expand, with 23 sites actively recruiting across Europe and 30 patients enrolled so far!
π A big thank you to everyone contributing!
ππ§ββοΈRecruit. Care. Cure. DO-IT!
π¨Exciting news! π¨
The first patient in the EU has been randomised into the @DOIT_trial ! ππ₯³
A big congratulations to Jonathan Coutinho and team in Amsterdam on this amazing achievement!
A huge thank you to everyone for making this possible!
Stay tuned for more updates.
β¨September was a busy and successful month for the @DOIT_trial β¨Another 3 centers are now active and recruiting.π
Thank you to the trial teams in Valladolid, Leuven, and Schleswig! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
β¨September was a busy and successful month for the @DOIT_trialβ¨
Another 4 centers are now active and recruiting.π₯³
Thank you to the trial teams in Madrid, Amsterdam, Charleroi, and Hamburg! We are thrilled to have you on board and welcome you to the @DOIT_trial and community.
Co-funding has been granted from the @TheBHF for the UK, DHF for the Netherlands, and Akershus University Hospital, internal open research funding for Norway. Thanks David Werring, Jonathan Coutinho, and Espen Kristoffersen and their teams for this great accomplishment.
π’Exciting newsπ’
28 trial sites in Germany, Spain, the Netherlands, and Belgium have received regulatory approval through CTIS!
The first trial sites in Germany+Belgium are now recruiting. Many additional trial sites have been submitted for approval!
π¨ University Hospital Basel is now an active site for the @DOIT_trial ! π§
We're one step closer to advancing stroke care for people suffering ischemic stroke despite #DOAC treatment.
Learn more π doit-trial.ch
#DOIT @StrokeBern
πBREAKING news! The second trial site for the DO-IT Trial has officially opened in St.Gallen! ππ We would like to welcome the trial team in St. Gallen to the DO-IT
community, we are thrilled to have you on board. Stay tuned for the upcoming site opening in Baselβ¦β²οΈ
π¨ Exciting news! π¨
The first patient has been randomised into the DO-IT Trial! π
A big congratulations to the trial team in Bern on this amazing achievement!
This marks a major milestone! A huge thank you to everyone for making this possible!
Stay tuned for more updates.
πBREAKING news! The first trial site for the DO-IT Trial has officially opened in Bern! ππ A big thank you to everyone involved for their support and hard work. Stay tuned for more updates on site openings across Swtizerland! π #DOITTrial





















