Screening Ultra-Large Encoded Compound Libraries Leads to Novel Protein-Ligand Interactions and High Selectivity dlvr.it/T1CYzc

SH3RF2 contributes to cisplatin resistance in ovarian cancer cells by promoting RBPMS degradation dlvr.it/T1BlpS

A new small molecule DoNA binding to CAG repeat RNA dlvr.it/T1B4B1

Unleashing the binding interaction of chrysin-Cu(II) complex with the biomacromolecular targets: further studies of cell cytotoxicity and radical scavenging properties dlvr.it/T16fYf

Pharmaceutical manifestation of Knoevenagel condensed metal (II) complexes through virtual, in vitro and in vivo assessments dlvr.it/T16fWV

Structures of kinetic intermediate states of HIV-1 reverse transcriptase DNA synthesis dlvr.it/T15sXK

Intrauterine arsenic exposure induces glucose metabolism disorders in adult offspring by targeting TET2-mediated DNA hydroxymethylation reprogramming of HNF4α in developing livers, an effect alleviated by ascorbic acid dlvr.it/T15Vby

Applications of cryo-EM in drug development for STING dlvr.it/T13qNz

Chemotherapeutic Mechanism of Action of the Synthetic Resorcinolic Methyl 3,5-dimethoxy-2-octanoylbenzoate dlvr.it/T13qN3

Ripretinib versus sunitinib in gastrointestinal stromal tumor: ctDNA biomarker analysis of the phase 3 INTRIGUE trial dlvr.it/T12kqP

Signal-off nanozyme-based colorimetric aptasensor for sensitive detection of ampicillin using MnO2 nanoflowers and gold nanoparticles dlvr.it/T12knt

Label-Free and Real-Time Optical Detection of Affinity Binding of the Antibody on Adherent Live Cells dlvr.it/T11QyM

Exploring the potential molecular mechanism of Gualou Guizhi decoction in the treatment of rheumatoid arthritis based on network pharmacology and molecular docking dlvr.it/T11Qy1

Consistency of drug-resistant mutations in plasma and peripheral blood mononuclear cells of patients with treatment-naïve and treatment-experienced HIV-1 infection dlvr.it/T10BvD

Synthesis and antitumor activity of cyclopentane-fused anthraquinone derivatives dlvr.it/T0zbYh

Identification of female-enriched and disease-associated microglia (FDAMic) contributes to sexual dimorphism in late-onset Alzheimer's disease dlvr.it/T0zbXK

Mechanisms of Endocrine Resistance in Hormone Receptor-Positive Breast Cancer dlvr.it/T0ygyG

Computational exploration of allosteric inhibitors targeting CDK4/CDK6 proteins: a promising approach for multi-target drug development dlvr.it/T0ygy5

Recognition of human telomeric G-quadruplex DNA by 1,5-disubstituted diethyl-amido anthraquinone derivative in different ion environments causing thermal stabilization and apoptosis dlvr.it/T0ygxw

Protein-DNA binding sites prediction based on pre-trained protein language model and contrastive learning dlvr.it/T0ygxT