@DLee133

Metabolism and stem cells. Old growth forests and lignomics. Also tweet about my puppy.

 Hboro, NC
Joined February 2017
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1/🧵Check out our new publication. “Multi-omic Rejuvenation and Lifespan Extension through Exposure to Youthful Circulation," which has been published in Nature Aging. nature.com/articles/s43587-0…

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Nature Aging - Heterochronic parabiosis ameliorates age-related diseases in mice, but how it affects epigenetic aging and long-term health was not known. Here, the authors show that in mice...

nature.com
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Multi-omic rejuvenation and life span extension on exposure to youthful circulation nature.com/articles/s43587-0…

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Nature Aging - Heterochronic parabiosis ameliorates age-related diseases in mice, but how it affects epigenetic aging and long-term health was not known. Here, the authors show that in mice...

nature.com
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A team of scientists has extended the lives of old mice by connecting their blood vessels to young mice. The study found infusions of youthful blood led the older animals to live 6-9% longer, roughly equivalent to six extra years for an average human. nyti.ms/3Qd6Suz

Blood of Young Mice Extends Life in the Old (Published 2023)

Infusions of youthful blood led older mice to live 6 to 9 percent longer, a new study found.

nytimes.com
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More here from David Lee. Data looks solid, look forward to more work including in other animal models ahead.🧑‍⚕️ xitter.cf/DLee133/status/1684738…
David Lee@DLee13328 Jul 2023
It is (finally) out! Great teamwork on this paper about aging and rejuvenation! Young circulation is acutely beneficial for an aged organism but thats old news… how long does the system need exposure to young🩸for the benefits to persist? nature.com/articles/s43587-0…

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Nature Aging - Heterochronic parabiosis ameliorates age-related diseases in mice, but how it affects epigenetic aging and long-term health was not known. Here, the authors show that in mice...

nature.com
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A team of scientists has extended the lives of old mice by connecting their blood vessels to young mice. The study found infusions of youthful blood led the older animals to live 6-9% longer, roughly equivalent to six extra years for an average human. nyti.ms/3OeVLP4

Blood of Young Mice Extends Life in the Old (Published 2023)

Infusions of youthful blood led older mice to live 6 to 9 percent longer, a new study found.

nytimes.com
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It is (finally) out! Great teamwork on this paper about aging and rejuvenation! Young circulation is acutely beneficial for an aged organism but thats old news… how long does the system need exposure to young🩸for the benefits to persist? nature.com/articles/s43587-0…

Multi-omic rejuvenation and lifespan extension on exposure to youthful circulation

Nature Aging - Heterochronic parabiosis ameliorates age-related diseases in mice, but how it affects epigenetic aging and long-term health was not known. Here, the authors show that in mice...

nature.com
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I was really impressed by that last “mock parabiosis” experiment (suggested during review but buried in Supp Fig 5). Whats the rejuvenation potential of young blood vs increasing physical activity and are those benefits maintained after the intervention is stopped?
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Great working with my co-1st Bohan Zhang! Total superstar! And glad to see Senior author Jim White getting more research out; tough starting a lab doing longevity work cause… well… life happens.
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And instantly an entire generation of grad students were allowed 4 more hours of sleep.
Matthew Watt@MattWattUnimelb11 Jul 2023
GTTs and ITTs: aim for shorter fasting times | Nature Metabolism- new data suggesting optimal fasting is 2 h for mice. nature.com/articles/s42255-0…
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Wait, ill join in on the discussion… I spent just 13 hours on a single R01……. Table.
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Im gunna get in so much trouble when i show this to my statistician wife. 😂☠️
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Im confused… isnt this like chickfila advertising that popeyes has the better chicken AND chickfila is still going to close on sundays?
nature
@Nature15 Oct 2022
The Science family of journals will soon allow authors to publicly share manuscripts more widely without incurring fees go.nature.com/3yIf10L
David Lee retweeted
nature
@Nature11 Oct 2022
Authors’ names have ‘astonishing’ influence on peer reviewers go.nature.com/3yxfh2C

Authors’ names have ‘astonishing’ influence on peer reviewers

Nature - A Nobel prizewinner is six times more likely than someone less well known to get a thumbs-up for acceptance, finds study.

nature.com
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Raleigh/Durham (triangle) has a huge fraction of work force in life science research.
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I want to know what IACUC approved this cause I’m over here getting yelled at about ‘expired’ deionized water bottles in a box of supplies 4 keycard access points away from the nearest cage of mice. n.pr/3teJTE5
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😂🤣🤣😂🤣🔥🔥🔥
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Looks like it’s gunna be one of those years in the lab…
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Finished PhD | Finished postdoc
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Replying to @joechakkal
Duke :) – at Ithaca, NY
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