Big news in oncology world as FDA approves daraxonrasib for metastatic pancreatic adenocarcinoma. So excited to see the real impact of research on human lives!
fda.gov/drugs/resources-info…
It’s fascinating to see the real impact of research on people’s lives.
KRAS-targeted therapy, especially in pancreatic cancer, is giving so many patients not just hope, but meaningful years of life ahead.
nejm.org/doi/full/10.1056/NE…
The expanded access program for daraxonrasib is available to patients with metastatic pancreatic cancer who have already received chemo, have good performance status (ECOG 0–1), and adequate organ function (albumin >3 and LFTs ≤3× normal).
clinicaltrials.gov/study/NCT…
Daria G retweeted
News: First CAR T-Cell Therapy Approved for Solid Tumors doi.org/10.1158/2159-8290.CD…
Every single day in heme/onc is an emotional marathon - equal parts resilience and sheer fascination. The rapid evolution of modern therapies that genuinely save lives and extend precious time with loved ones never stops amazing me
S-CUL3KO model demonstrated impaired renal baroreceptor mechanism leading to hypertension.
Thanks to our collaborators and colleagues!
More on the mechanism of HTN in S-CUL3KO ➡️ insight.jci.org/articles/vie…
Daria G retweeted
Work form @MCWPhysiology
No pressure—but if the renal baroreceptor machinery piques your curiosity...
@curtsigmund & team @MedicalCollege reveal mice lacking CUL3 in vascular smooth muscle cells exhibit robust hypertension with paradoxically unaltered renin expression and decreased integrin β1 expression.
See the full report: insight.jci.org/articles/vie…
Daria G retweeted
No pressure—but if the renal baroreceptor machinery piques your curiosity...
@curtsigmund & team @MedicalCollege reveal mice lacking CUL3 in vascular smooth muscle cells exhibit robust hypertension with paradoxically unaltered renin expression and decreased integrin β1 expression.
See the full report: insight.jci.org/articles/vie…
Thrilled to share our latest work uncovering a key vascular mechanism contributing to hypertension in S-CUL3KO model!
Grateful to have worked with such an amazing team @MCWPhysiology @HyperAHA @CurtSigmund @NakagawaPablo
Check out our findings here: ahajournals.org/doi/full/10.…
More cookies for the Bake Sale have arrived! Thanks to our sponsors @crumbl and Nothing Bundt Cakes!
@MCW_Postdoc
Our proud sponsors! Come join us for a bake sale to help animals in need! @MCW_Postdoc @MCWPhysiology
@crumbl
Paws 🐾 for a Cause 🐱
justgiving.com/page/pawsfora…
Postdoc Advisory Committee is fundraising for Wisconsin Humane Society. Check out their @JustGiving page and please donate if you can to support our furry friends!
Thank you! #JustGiving #pawsforacause @MCW_Postdoc
justgiving.com/page/pawsfora…
I’m so honoured and grateful to receive this award! Thank you to Jan Lennon for her continuous support and sponsorship of this Award!
We congratulate Daria Golosova, MD, PhD, on winning the 2024 Edward J. Lennon, MD, Outstanding Woman Postdoctoral Researcher Award and wish her continued success. Daria received the award from the esteemed Jan Lennon, the sponsor of this honor. @DGphysiology
Daria G retweeted
Explore a career in nephrology with the 2025 Kidney TREKS Program! 🌟 Explore Bar Harbor, ME, or Chicago, IL, and connect with a mentor to grow your research and career.
Deadline: January 22, 2:00 p.m. EST.
Apply Now! 🔗asn-online.org/treks
📷 Credits: Arvin Halim
Daria G retweeted
There is renin in the brain!!!!!! Great job team from @MCWPhysiology. Definitive Evidence for the Identification and Function of Renin-Expressing Cholinergic Neurons in the Nucleus Ambiguus | Hypertension ahajournals.org/doi/abs/10.1…
Daria G retweeted
The 2024 #NobelPrize laureates in chemistry Demis Hassabis and John Jumper have successfully utilised artificial intelligence to predict the structure of almost all known proteins.
In 2020, Hassabis and Jumper presented an AI model called AlphaFold2. With its help, they have been able to predict the structure of virtually all the 200 million proteins that researchers have identified. Since their breakthrough, AlphaFold2 has been used by more than two million people from 190 countries. Among a myriad of scientific applications, researchers can now better understand antibiotic resistance and create images of enzymes that can decompose plastic.
Read more about their story: bit.ly/3XI7KK3
Daria G retweeted
Beautiful talk by @NakagawaPablo on RAS spatial transcriptomics in brain, session chaired by @FZMarques @CVR_TomaszGuzik @ish_2024
Don’t miss a chance to learn more about immigration and visa opportunities in the USA! Brendan Delaney, an immigration attorney, will open up some secrets just for @MCW_Postdoc
@nationalpostdoc @CVCatMCW #NPAW2024 @MCWPhysiology
