Out now in @MolecularCell: Cyanobacterial Argonautes and Cas4 family nucleases cooperate to interfere with invading DNA
cell.com/molecular-cell/full…
Most long-A pAgos interfere with invading DNA solo. Why then are cyanobacterial pAgos co-encoded with a Cas4-like protein?
A 🧵
The first steps of this work were taken a long time ago during my @EMBO fellowship in the Jinek lab @UZH_en, but the main work was carried out by the talented @pilar_bobadilla in our group @WageningenUR @ERC_Research.
In addition @SumanthMutte @TNiault @BarendsePatrick @BalwinaK and many other X-less coauthors. With further help of collaborator @hauryliuk!
Thanks to all who contributed to this multidisciplinary study!
Daan C. Swarts retweeted
A PhD position is open for this year. A candidate should have a background in programming skills.
Excited to have been awarded an ERC Proof-of-Concept grant to further explore the possibilities to use prokaryotic Argonautes for diagnostics applications! 🥳
📣 Out now! Final results of the 2024 ERC #Proof of #Concept #Grant call for proposals for #funding.
134 researchers will receive €150k each to explore the commercial or societal potential of their frontier #research results.
👉 europa.eu/!cGG9jc
#ERCPoC @EUScienceInnov
Daan C. Swarts retweeted
Young RNA biologist and others: The deadline for these attractive group leader positions is this weekend!
🚨New review🚨
Evolution and ecology of anti-defence systems in phages and plasmids
Link: cell.com/current-biology/ful…
We propose that beyond unraveling new anti-defence mechanisms, efforts should also aim to clarify the evolutionary and ecological drivers of anti-defence systems, which currently remain poorly explored.
Together with @TNiault, it was really fun to (again) work together with former colleagues and friends @edzewestra and @StinekevanHoute on this review!
Hope that everyone interested enjoys the read!











