@CunniffLab

The Cunniff lab is interested in how mitochondrial dynamics influence cell processes and is identifying new therapeutics targets for aggressive cancers.

Joined July 2019
  • Tweets170
  • Following120
  • Followers147
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News from @UVMcancercenter and @RedoxVT, the Redox Biology and Pathology Program at #UVMLarnerMed.
UVM Cancer Center@UVMcancercenter13 Jun 2024
NEW @NatureCellBio study finds glutathione S transferase theta drives pancreatic cancer metastasis by targeting fibronectin which places redox reactions front and center in tumor metastatic behavior. Congrats @RedoxVT on supporting these findings! go.nature.com/4aVXWAE
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#ASCO24 Abstracts have been published! See the short list of rapid oral abstracts in Developmental Therapeutics - Molecularly Targeted Agents & Tumor Biology and you will see our first-in-human phase 1 for RSO-021 @dean_fennell @CunniffLab @PRCLeicester tinyurl.com/ASCO24
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Happy to announce our abstract has been approved 👏👏 #BTOG24 Our CSO Brian Cunniff, Phd, @CunniffLab will be presenting "First-in-class peroxiredoxin 3 (PRX3) inhibitors" poster. Stop by the welcome reception Wednesday April 17th, 18:30 – 20:00, say hello or ask questions.
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Cunniff Lab retweeted
NilsBurger@burger_nils20 Feb 2024
Happy to share our review with @echouchani on recent advances in cysteine proteomics! @HarvardCellBio @DFCI_CancerBio authors.elsevier.com/c/1idmT…
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We are proud to announce we have 2 abstracts accepted for the @AACR Annual Meeting 2024 in San Diego. 👏 We will present our posters in session "Other Cellular Mechanisms for Anticancer Drug Action" and "Cellular Stress Responses 1" See you in🌞SD! @CunniffLab @dean_fennell
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Our team presenting our MITOPE phase 2 study of novel therapies for #mesothelioma and #lungcancer with malignant pleural effusions to #nurses at @HASAG education workshop in #London 👏
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The MPBP Department in @UVMLarnerMed is collaborating with @UVMcancercenter to recruit a new colleague. Please RT. uvmjobs.com/postings/67098
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Thankful to Mike & Patricia Butler thebutlerfoundation.com
Mike & Patricia Butler, hosts of the 15th Annual Kentucky Derby event

ALT Mike & Patricia Butler, hosts of the 15th Annual Kentucky Derby event

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Cunniff Lab retweeted
RedoxVT@RedoxVT17 Apr 2023
We are excited to share @CunniffLab is heading to Florida to present their ongoing work in anticancer #immunotherapy at the @AACR Annual meeting!
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#ELCC23:Mesothelioma treatment: From hopeless to hopeful Recipient of the Heine H. Hansen Award 2023, Paul Baas charts the course of mesothelioma treatment over the last 30 years and warns that progress has been made only in some areas of the world. 👉ow.ly/6vMA50NvACa
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Cunniff Lab retweeted
RedoxVT@RedoxVT13 Mar 2023
PhD student Nate Shannon gave a great update on his research examining the molecular mechanisms whereby subcellular positioning of mitochondria affects cell biology! Great new insights into the role of Miro1. Nate works in the @CunniffLab
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Cunniff Lab retweeted
RedoxVT@RedoxVT27 Jan 2023
RBP faculty and trainees took a field trip to the new @agilent Laboratory for Chemical Analysis at UVM. Thank you Drs.Petrucci and O’Rourke for presenting the capabilities and workflow of these resources. This will provide wonderful opportunities for discovery in our labs!
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Cunniff Lab retweeted
Mesothelioma UK@Mesouk23 Jan 2023
We'd like to say a huge thank you to @RSOncologyLLC, a clinical stage biotechnology company based in Cambridge, Massachusetts in the US, who donated to Mesothelioma UK to support our Clinical Nurse Specialist team. You can read more on our website ow.ly/RwKQ50Mxv7v
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Excellent talk by graduate student @javed_zaineb26 from our lab @UPMCHillmanCC on mitochondrial fission regulation, presented at #SfRBM22. Looking forward to more great science tomorrow
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TODAY at Noon! The @UVMLarnerMed 2022 Research Laureate Lecture “#Redox Medicine for the Management of Chronic Diseases” presented by #UVM Cancer Center member Yvonne Janssen-Heininger, Ph.D., Professor of Pathology and Laboratory Medicine. @UVMResearch med.uvm.edu/research/excelle…
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Exciting news! Our abstract is now published. Read about our #keyfindings and first-in-human #clinicaltrial for cancer patients with unmet medical needs. #changinglives #cancertherapy annalsofoncology.org/article…

1643TiP First-in-human dose-escalation and expansion study (MITOPE) to evaluate mitochondrial PRX3...

Tumor cells generate elevated levels of reactive oxygen species (ROS) and therefore exhibit increased expression and activity of critical ROS scavenging pathways, including the mitochondrial peroxide...

annalsofoncology.org
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Cunniff Lab retweeted
CMB @ UVM@uvmcmb28 Feb 2022
Congratulations to CMB student Sierra Bruno who successfully defended her dissertation titled, “Mitochondrial dynamic regulation of the lung epithelial response to complex allergen”👏👏👏 @UVMGradCollege @UVMLarnerMed
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More great partnership news supporting #UVMresearch uvm.edu/news/story/agilent-a…
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Looking for a great conference to attend in 2022? Look no further!
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The Future of Redox Biology meeting in Sienna, Italy 17-19 June 2022. ECR focused and further information and programme available soon @SFRBM @SFRBM @FEBSnews @BiochemSoc
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