@CreweLab
Joined September 2022
  • Tweets68
  • Following196
  • Followers275
5Media
The Crewe lab is looking for a postdoc to study adipose extracellular vesicle signaling in cardiovascular disease. Send me an email if you are interested!
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Tick-tock! 🕒 Don’t miss your chance to showcase your research at the Kern Lipid Conference. Make sure to submit your abstract or award application before the April 1st deadline. Details here: kernconference.org/awards.ht…
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The first paper from the Crewe lab is online today. We found that macrophage-meditated clearance of EVs is a major determinate of circulating adipocyte EV levels. This clearance is disrupted in obesity. A huge effort by Snigdha Tiash! cell.com/cell-metabolism/ful…
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Clair Crewe retweeted
Dan Lark@ERM_Lab
23 Apr 2025
Final version of our new paper "Mapping Organism-wide Single Cell mRNA Expression Linked to Extracellular Vesicle Biogenesis, Secretion, and Cargo" is now available Open Access. academic.oup.com/function/ar…

Function

journals.physiology.org
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Gemma Conroy @Nature wrote a fantastic news feature on #mitochondria transfer. It’s exciting to see so much interest! Many good friends and colleagues highlighted here! Check it out. nature.com/articles/d41586-0…

Cells are swapping their mitochondria. What does this mean for our health?

Nature - Researchers are studying why the energy factories are moving between cells and whether the process can be harnessed to treat cancer and other diseases.

nature.com
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Speaker Spotlight: Dr. Rana Gupta (@DukeU) Join us @ #AdiposeBiology Conference in Montreal🇨🇦, Aug 19-20, 2025, to hear from Rana about #adiposedevelopment. Don’t miss his talk! 🔗 Register now – adiposebiology.com #ABC2025 #Metabolism #Adipogenesis #ObesityResearch
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Scientists are now organizing events, called Stand Up for Science, on 7 March in Washington, D.C., and state capitals. scim.ag/3XlYkEu @NewsfromScience

‘I really wanted something to happen.’ The students behind the Stand Up for Science protests

New group hopes to turn out researchers for 7 March demonstrations against Trump administration policies

science.org
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Strong article from Tom Maniatis, head of the NY Genome Center, on the history of the NIH and its role in maintaining U.S. scientific leadership. Safeguarding the future of biomedical science in the United States: Cell cell.com/cell/fulltext/S0092…

Safeguarding the future of biomedical science in the United States

NIH’s abrupt decision to cap indirect cost reimbursement at 15% threatens the critical infrastructure supporting groundbreaking biomedical research in the United States. This policy jeopardizes...

cell.com
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I’m excited to share that my thesis work on brown adipocyte-secreted proteins and their role in regulating Type 1 Diabetes is now published! Huge thanks to @ThePistonLab and collaborators! diabetesjournals.org/diabete…

Regulation of Type 1 Diabetes via Brown Adipocyte–Secreted Proteins and the Novel Glucagon Regula...

Current treatments for type 1 diabetes (T1D) focus on insulin replacement. We demonstrated the therapeutic potential of a secreted protein fraction from em

diabetesjournals.org
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Transforming traditional views laid by “CNS immune privilege,” our research uncovers the brain’s purposeful presentation of self – that is the brain engages with the immune system through “guardian” peptides to ensure immune tolerance. @jonykipnis nature.com/articles/s41586-0…

Endogenous self-peptides guard immune privilege of the central nervous system

Nature - Central nervous system (CNS)-derived regulatory self-peptides are essential for maintaining a continuous dialogue between the CNS and the immune system while balancing overt autoreactivity.

nature.com
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The first conference for horizontal mitochondrial transfer #HMTD24 just wrapped up in Prague. Amazing people and science in this developing field!
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Very excited to share our latest paper out today @NatMetabolism showing that #mitochondria transfer and transplantation may reduce the morbidity and mortality of #LeighSyndrome, a fatal mitochondrial disease with no effective therapies. dlvr.it/TCjPl6

Mitochondria transfer-based therapies reduce the morbidity and mortality of Leigh syndrome

Nature Metabolism - Administration of exogenous mitochondria from mice or humans, or stimulation of mitochondria transfer from haematopoietic cells through bone marrow transplant from wild-type...

nature.com
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If you are new to extracellular vesicle research and want some guidance on how to study them in metabolic regulation check out our comment in @NatMetabolism. Thank you Dan Lark @ERM_Lab, Kerstin Stemmer, and Wei Ying for these insights! nature.com/articles/s42255-0…
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Clair Crewe retweeted
Natalie Niemi@nieminm
23 Aug 2024
Really excited to share our latest paper describing the MitoLuc assay for quantitative mitochondrial protein import, which we wrote in collaboration with @IanofBristol! sciencedirect.com/science/ar…
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Headed to #ENDO2024! I’m looking forward to learning about outstanding clinical research!
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“For centuries, scholars from around the world have called Boston home or traveled here for research and immersion.” — Mayor Michelle Wu | Register for #ENDO2024 (bit.ly/48Iuei2) and join us in beautiful Boston, MA. Read the mayor’s letter welcoming the conference to the city in June (bit.ly/44lJT5B). #endocrinology  #hormonescience
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Lab lunch under the #SolarEclipse2024
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Clair Crewe retweeted
CK Chen Lab@CKChenLab
1 Apr 2024
Want to learn more about circular RNAs and immunity? Come join our CB&P Seminar tomorrow (April 1st) at 1:00 PM!
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We are looking for a postdoc! If you are interested in obesity/type 2 diabetes and extracellular vesicles apply below! wustl.wd1.myworkdayjobs.com/…
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Clair Crewe retweeted
WUSTL ABBGS@WUSTLABBGS
15 Feb 2024
As Black scientists, we usually face unique challenges in academia. Often feeling isolated. Come learn how Doctors Rita Brookheart and Bettina Blake navigated their journeys!!! There will be food!!! 🍰 Edited · 12s
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