@CosrLab

Center for Omics Sciences @SanRaffaeleMI. Promoting multi-omics research to understand diseases development, diagnosis and cure. Tweets are our own view

 Milano, Lombardia
research.hsr.it/en/centers/omics-sciences.html
Joined February 2019
  • Tweets869
  • Following777
  • Followers691
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Discover how to reveal and harness CD39 for the treatment of #colorectalCancer and liver #metastases by engineered #Tcells reading our brilliant work recently published in @Gut_BMJ by Alessia Potenza, @balestrc @CosrLab @BoniniChiara and collaborators gut.bmj.com/content/early/20…
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🧬 "SurfR: Riding the wave of RNA-Seq data with a comprehensive Bioconductor package to identify Surface Protein Coding Genes" introduces SurfR, an R package enabling streamlined analysis of surface protein genes from #RNASeq data. Read more: doi.org/10.1093/bioadv/vbae2… #DataAnalysis @aurora_maurizio @ASTascini
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💻 SurfR, a comprehensive R/Bioconductor package for surface protein gene analysis from RNA-Seq data, is available with source code, tutorials, and use cases on GitHub: github.com/auroramaurizio/Su… #OpenSource #ComputationalBiology #GeneAnalysis

GitHub - auroramaurizio/SurfR_UseCases: R code for SurfR Bioconductor package use cases

R code for SurfR Bioconductor package use cases. Contribute to auroramaurizio/SurfR_UseCases development by creating an account on GitHub.

github.com
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Happy to present our #spatialomics 🔍🗺️work on #esophageal cancer @EACRnews Genomics multiOmics and computational biology meeting! Great program, inspiring talks and good friends! GiuliaLopatrielllo GiuseppinaArbore @OSanraffaele @COSRLab #cosmx
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Kudos to @ValentinaGiansa for this and thanks to all people involved! 👇👇👇 Scalable Integration of Multiomic Single Cell Data Using Generative Adversarial Networks academic.oup.com/bioinformat…

Scalable integration of multiomic single-cell data using generative adversarial networks

AbstractMotivation. Single-cell profiling has become a common practice to investigate the complexity of tissues, organs, and organisms. Recent technologica

academic.oup.com
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New lab pic? @ValentinaGiansa @LilloCarlin0 #retreatosr2024
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Happy our SurfR package has been accepted in bioconductor! A a bioinformatics R package to surf the cells’ surfaceome starting from NGS data #bioinformatics #surfaceome #Rpackage @CosrLab @ASTascini @marcojmorelli github.com/auroramaurizio/Su…
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Please help me #RT this 2-years postdoc position #Bioinformatics / #DataScience at the crossing of single-cell #Genomics and #longreads sequencing. With @UniTrieste and @AreaSciencePark in Trieste! Fun work, people and science: more on #LinkedIn linkedin.com/jobs/view/37928…

Offerte di lavoro per Ricercatore qui: Italia ( (Posizioni aperte (65))) | LinkedIn

Le principali offerte di lavoro di oggi per Ricercatore. 65 qui: Italia. Sfrutta la tua rete professionale e fatti assumere. Nuove offerte di lavoro per Ricercatore ogni giorno.

it.linkedin.com
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Attention please! 📣Registration to the yearly event of our association @ERCinItaly are now OPEN! Register here: ercinitaly.eu/evento-ercinit… Be part of the Italian frontier research community!
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Merry Christmas and happy new year from @CosrLab 🎅🎄⭐️🥂❄️ #Christmas2023
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"This is an excellent study!" The rev said. Check out our peripheral #nerve #regeneration paper at authors.elsevier.com/c/1i5ab… Congrats to the brilliant distinguished gentlemen Dario Bonanomi and Ganesh Bhat, dear @COSRLab colleagues @ilDepoMI and Santo Diprima, and all authors!
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💥BIG PAPER ALERT💥 So excited to share our latest, out now @Nature! Here, we uncover a spatially confined interplay between subsets of IL-1b+ macrophages and tumor cells that fuels pathogenic inflammation in pancreatic cancer (1/n) nature.com/articles/s41586-0…

IL-1β+ macrophages fuel pathogenic inflammation in pancreatic cancer

Nature - Single-cell and spatial gene expression analyses of pancreatic ductal adenocarcinoma uncover a population of interleukin-1β-expressing macrophages that drive inflammatory...

nature.com
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Join us at SR-TIGET in Milan! We are recruiting a PhD student to study how #telomeric damage contributes to defective #immunity as part of a fantastic international consortium @IMMERGE_MSCA_DN, a #MSCAction #DoctoralNetwork. @MyUniSR @Telethonitalia @SanRaffaeleMI. Apply below👇
IMMERGE@IMMERGE_MSCA_DN4 Oct 2023
📢@IMMERGE_MSCA_DN is a #MSCActions #DoctoralNetwork (DN) aiming to train a New Generation of Scientists in Europe in #immunology, #multiomics & #GeneEditing to fight against #PrimaryImmunodeficiencies We just opened the call! 📯 📯 📯 Find out more 🔎 👉immergeproject.eu
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36 datasets, 26 protocols, 1.7 million harmonized cells! First edition Human Neural Organoid Cell Atlas. Important work from @zhisong_he @josch_f Leander Dony @TreutleinLab @fabian_theis. Strong community effort @Sergiu_P_Pasca @GiorgiaQuadrato. #organoids @ETH_BSSE @IHB_Research
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Un nostro nuovo studio apre nuove strade per lo sviluppo di immunoterapie innovative per curare il tumore del colon-retto. hsr.it/news/2023/ottobre/svi…

Tumore colon-retto e nuove prospettive di cura: lo studio del San Raffaele

Un nuovo studio del San Raffaele apre nuove strade per lo sviluppo di immunoterapie innovative per curare il tumore del colon-retto: approfondisci.

hsr.it
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Colorectal cancer: study of the tumor microenvironment opens up new possible immunotherapies. It has been demonstrated by researchers of the @sararaffaeleMI and UniSR, led by Chiara Bonino. Find out more : hubs.ly/Q023-2kk0
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Check out the paper featured on the cover of this month’s Cancer Research: Preexisting Immunity Drives the Response to Neoadjuvant #Chemotherapy in Esophageal #Adenocarcinoma, by Arbore et al. bit.ly/45U1GjX
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Two papers characterizing the critical role of CD8+ T cell subsets in COVID vaccination and infection - now in @NatImmunol! * @EJohnWherry lab (@markmpainter): nature.com/articles/s41590-0… * Our collab. w/Dan Littman's lab (@Bingjie_Zhang_+Rabi Upadhyay): nature.com/articles/s41590-0…

Prior vaccination promotes early activation of memory T cells and enhances immune responses during...

Nature Immunology - Wherry and colleagues define the kinetics of vaccine-primed recall immune responses during severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) breakthrough infection,...

nature.com
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Excited that veloVI is out @naturemethods! Led by @adamgayoso & @PhilippWeiler7 w awesome @YosefLab, we combine deep generative modeling with a mechanistic single-cell transcriptional model for better RNA velocity analysis with uncertainty quantification. nature.com/articles/s41592-0…
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Don’t miss this publication by @DCampolungo and Gabellini lab. Happy I had the chance to contribute to this incredible work unraveling DUX4-r role in acute lymphoblastic leukemia | @ScienceAdvances science.org/doi/10.1126/scia…

DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia

DUX4-r oncogenic activity requires GTF2I, whose targeting abrogates DUX4-r chromatin binding and target activation in leukemia.

science.org
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Acute lymphoblastic #leukemia is the most frequent tumor in childhood. Two studies from San Raffaele may help to identify further prognostic criteria earlier and better personalize treatments for this particular leukemic form. Read more: hubs.ly/Q022w06J0
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