@CosLigorio

Research Fellow in @Mata_Lab | Building biomaterials for regenerative medicine using proteins and peptides | 🇮🇹🇬🇧

 Nottingham, England
bit.ly/3prYuHX
Joined January 2012
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I am so proud to share our latest article published today on Advanced Materials. Here we introduce the unparalleled opportunity to exploit synthetic peptides to biocooperate with blood for the creation of autologous, tuneable, regenerative implants. shorturl.at/gCWtZ

Biocooperative Regenerative Materials by Harnessing Blood‐Clotting and Peptide Self‐Assembly

Nature has evolved to repair small fractures by leveraging the cellular and molecular components of regenerative hematoma (RH). This study introduces a biocooperative material approach that enables...

advanced.onlinelibrary.wiley.com
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Great work. Check it out!
Peptide BioNanomaterials Group@PBN_GroupFeb 4
Read our recent work in #Small @AdvPortfolio We demonstrated charge guided selective co-assembly of peptides allowing for governing β-sheet alignment, co-assembly kinetics, fiber nanomorphology, & network structure. onlinelibrary.wiley.com/doi/…

Charge Directed Selective Co‐Assembly of Ionic Complementary Peptide Binary Mixtures

Multi-component peptide systems enable the development of multi-functional and tunable materials, yet, controlling the co-assembly of such complex systems remains challenging. This study demonstrat...

onlinelibrary.wiley.com
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Congratulations to Dr Cosimo Ligorio and Professor Alvaro Mata on being shortlisted in the Collaborate to Innovate (C2I) Awards for their work on peptide-blood hydrogels for bone regeneration @TheEngineerUK @UoN_Pharmacy #C2IAwards Read more here ➡️ bit.ly/4nVUuMY
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Cosimo Ligorio retweeted
Massimo
@Rainmaker197312 Nov 2025
When chemistry paints its masterpiece
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I had the fantastic opportunity to present my work on biocooperative materials at ESB 2025. Great symposia, great opportunity for discussions.
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Congratulations to @IreneChiesa22 & co-authors for this beautiful paper on 4D bioprinting of trachea that got the cover of Advanced Materials Technologies @AdvPortfolio #ProudPI @CPiaggioUniPisa @CHOP_Research @ChildrensPhila @Unipisa @pennbioeng @Penn_ENT advanced.onlinelibrary.wiley…
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The art and science of collaboration in bioengineering research bit.ly/4l2GrVB
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Check out this great review! doi.org/10.1002/adhm.2024023… @Mata_Lab

A Comparison of the Mechanical Properties of ECM Components and Synthetic Self‐Assembling Peptides

Self-assembling peptide hydrogels are increasingly utilized in biomedical applications. The authors review the key mechanical properties of these structures across multiple size scales and compare...

advanced.onlinelibrary.wiley.com
The Mata Lab@Mata_Lab20 Feb 2025
Check out Alex's review comparing mech properties of fibrous ECM components and self-assembling peptide nanofibres. An effort to contribute towards the rational design of tissue engineered matrices. @AOCMF_BOOST @NottmBRCMSIR @UKRMP_Smart @UoN_RMCT @UoN_BDI @UoN_SoE @philmw
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New publication! Here, we presented a label-free methodology using in vitro tests, OrbiSIMS & SRS to reveal how cosmetic peptides penetrate human skin, self-assemble with endogenous molecules, and restore skin hydration and mechanics bit.ly/3D0HDHN @Mata_Lab @UoN_BDI

Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction...

Abstract. Self-assembling peptides (SAPs) represent a rich source of building blocks that interact with biological structures. For instance, cosmetic SAPs

pubs.acs.org
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Biomaterial design for proactive modulation of the complement system bit.ly/40XTHBJ
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'Once-in-a-century' discovery in Pompeii reveals gold coins, pearl earrings and a sumptuous private bathhouse bbc.in/4atcvNp
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Our article entitled ‘Disassembly of self-assembling peptide hydrogels as a versatile method for cell extraction and manipulation’, has been featured in the J of Mater Chem B 2024 Most Popular Articles collection. Free to access until 28 Feb 2025 shorturl.at/ETcQM @Mata_Lab
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Read our recent work in #Small @AdvPortfolio unveiling how electrostatic interactions govern lateral association of peptide β-sheet nanofibers. Important mechanistic insights for understanding of peptide nanofibres formation & protein fibrillation onlinelibrary.wiley.com/doi/…

Unraveling the Atomistic Mechanism of Electrostatic Lateral Association of Peptide β‐Sheet Struct...

Guiding molecular assembly of peptides remains a major hurdle against the development of rationally designed nanomaterials. This study unveils how electrostatic interactions govern self-assembly and...

onlinelibrary.wiley.com
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Cosimo Ligorio retweeted
Lega Serie A
@SerieA_EN6 Jan 2025
WHAT A COMEBACK. WHAT A GAME. @acmilan have won the #EASPORTSFCSupercup! 🏆❤️🖤
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Thank you @RobSissons1 from @BBCNews for covering our story. bbc.com/news/articles/c4g20y… @Mata_Lab @NottmBRCMSIR @AOCMF_BOOST

Study says patient blood could repair broken bones

Scientists have transformed blood into a substance which successfully repaired bones in animals.

bbc.com
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Cosimo Ligorio retweeted
Hien Tran@HienATran17 Nov 2024
Happy to share that our paper published:doi.org/10.1002/smll.2024079…. A big thanks to my wife,@JelenaRnjak and @Khoonono for endless support. Also, a grateful to our collaborators for invaluable contributions, Thanh,@KaplanLab_Tufts,@jugalsahoo, Onur, Quin, Do, @KrisKilian, @docswise.

Probing the Interplay of Protein Self‐Assembly and Covalent Bond Formation in Photo‐Crosslinked...

This study explores the interplay between self-assembly and di-tyrosine bond formation in silk fibroin hydrogels photo-crosslinked with ruthenium and sodium persulfate. The resultant dual crosslink...

onlinelibrary.wiley.com
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It's fantastic to see the growing interest in our article! Here is some of the media coverage we got: independent.co.uk/news/scien… @Mata_Lab @NottmBRCMSIR @UoNresearch @UoN_BDI @AOCMF_BOOST @UoNPressOffice

Patients’ own blood could be used to help repair broken bones, study suggests

Scientists have transformed blood into a material which successfully repaired bones in animals.

independent.co.uk
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@UoN_BDI @UoNresearch @Mata_Lab @AOCMF_BOOST @NottmBRCMSIR
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Cosimo Ligorio retweeted
Keenan Crane
@keenanisalive14 Nov 2024
We often think of an "equilibrium" as something standing still, like a scale in perfect balance. But many equilibria are dynamic, like a flowing river which is never changing—yet never standing still. These dynamic equilibria are nicely described by so-called "detailed balance"
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Cosimo Ligorio retweeted
AC Milan
@acmilan5 Nov 2024
What a performance. What a game. To a man, the Rossoneri were brilliant tonight. Bravi ragazzi!!! 👏 #RealMilan #UCL #SempreMilan
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